A Many-Faced Alkaloid: Polymorphism of (–)-Monophyllidin

por Dank, Christian, Wurzer, Richard, Felsinger, Susanne, Bugl, Ricarda, Kählig, Hanspeter, Hela, Wolfgang, Roller, Alexander, Gstach, Hubert
Publicado 2020

KRAS Binders Hidden in Nature

por Bergner, Andreas, Cockcroft, Xiaoling, Fischer, Gerhard, Gollner, Andreas, Hela, Wolfgang, Kousek, Roland, Mantoulidis, Andreas, Martin, Laetitia J., Mayer, Moriz, Müllauer, Barbara, Siszler, Gabriella, Wolkerstorfer, Bernhard, Kessler, Dirk, McConnell, Darryl B.
Publicado 2019

Targeted Synthesis of Complex Spiro[3H‐indole‐3,2′‐pyrrolidin]‐2(1H)‐ones by Intramolecular Cyclization of Azomethine Ylides: Highly Potent MDM2–p53 Inhibitors

por Gollner, Andreas, Weinstabl, Harald, Fuchs, Julian E., Rudolph, Dorothea, Garavel, Geraldine, Hofbauer, Karin S., Karolyi‐Oezguer, Jale, Gmaschitz, Gerhard, Hela, Wolfgang, Kerres, Nina, Grondal, Elisabeth, Werni, Patrick, Ramharter, Juergen, Broeker, Joachim, McConnell, Darryl B.
Publicado 2018

Getting a Grip on the Undrugged: Targeting β‐Catenin with Fragment‐Based Methods

por Kessler, Dirk, Mayer, Moriz, Zahn, Stephan K., Zeeb, Markus, Wöhrle, Simon, Bergner, Andreas, Bruchhaus, Jens, Ciftci, Tuncay, Dahmann, Georg, Dettling, Maike, Döbel, Sandra, Fuchs, Julian E., Geist, Leonhard, Hela, Wolfgang, Kofink, Christiane, Kousek, Roland, Moser, Franziska, Puchner, Teresa, Rumpel, Klaus, Scharnweber, Maximilian, Werni, Patrick, Wolkerstorfer, Bernhard, Breitsprecher, Dennis, Baaske, Philipp, Pearson, Mark, McConnell, Darryl B., Böttcher, Jark
Publicado 2021

Drugging an undruggable pocket on KRAS

por Kessler, Dirk, Gmachl, Michael, Mantoulidis, Andreas, Martin, Laetitia J., Zoephel, Andreas, Mayer, Moriz, Gollner, Andreas, Covini, David, Fischer, Silke, Gerstberger, Thomas, Gmaschitz, Teresa, Goodwin, Craig, Greb, Peter, Häring, Daniela, Hela, Wolfgang, Hoffmann, Johann, Karolyi-Oezguer, Jale, Knesl, Petr, Kornigg, Stefan, Koegl, Manfred, Kousek, Roland, Lamarre, Lyne, Moser, Franziska, Munico-Martinez, Silvia, Peinsipp, Christoph, Phan, Jason, Rinnenthal, Jörg, Sai, Jiqing, Salamon, Christian, Scherbantin, Yvonne, Schipany, Katharina, Schnitzer, Renate, Schrenk, Andreas, Sharps, Bernadette, Siszler, Gabriella, Sun, Qi, Waterson, Alex, Wolkerstorfer, Bernhard, Zeeb, Markus, Pearson, Mark, Fesik, Stephen W., McConnell, Darryl B.
Publicado 2019

Reply to Tran et al.: Dimeric KRAS protein–protein interaction stabilizers

por Kessler, Dirk, Gollner, Andreas, Gmachl, Michael, Mantoulidis, Andreas, Martin, Laetitia J., Zoephel, Andreas, Mayer, Moriz, Covini, David, Fischer, Silke, Gerstberger, Thomas, Gmaschitz, Teresa, Goodwin, Craig, Greb, Peter, Häring, Daniela, Hela, Wolfgang, Hoffmann, Johann, Karolyi-Oezguer, Jale, Knesl, Petr, Kornigg, Stefan, Koegl, Manfred, Kousek, Roland, Lamarre, Lyne, Moser, Franziska, Munico-Martinez, Silvia, Peinsipp, Christoph, Phan, Jason, Rinnenthal, Jörg, Sai, Jiqing, Salamon, Christian, Scherbantin, Yvonne, Schipany, Katharina, Schnitzer, Renate, Schrenk, Andreas, Sharps, Bernadette, Siszler, Gabriella, Sun, Qi, Waterson, Alex, Wolkerstorfer, Bernhard, Zeeb, Markus, Pearson, Mark, Fesik, Stephen W., McConnell, Darryl B.
Publicado 2020