Synergistic Rescue of Nonsense Mutant Tumor Suppressor p53 by Combination Treatment with Aminoglycosides and Mdm2 Inhibitors

por Zhang, Meiqiongzi, Heldin, Angelos, Palomar-Siles, Mireia, Öhlin, Susanne, Bykov, Vladimir J. N., Wiman, Klas G.
Publicado 2018

Novel compounds that synergize with aminoglycoside G418 or eRF3 degraders for translational readthrough of nonsense mutant TP53 and PTEN

por Heldin, Angelos, Cancer, Matko, Palomar-Siles, Mireia, Öhlin, Susanne, Zhang, Meiqiongzi, Sun-Zhang, Alexander, Mariani, Anna, Liu, Jianping, Bykov, Vladimir J.N., Wiman, Klas G.
Publicado 2023

Chemical regulators of epithelial plasticity reveal a nuclear receptor pathway controlling myofibroblast differentiation

por Carthy, Jon M., Stöter, Martin, Bellomo, Claudia, Vanlandewijck, Michael, Heldin, Angelos, Morén, Anita, Kardassis, Dimitris, Gahman, Timothy C., Shiau, Andrew K., Bickle, Marc, Zerial, Marino, Heldin, Carl-Henrik, Moustakas, Aristidis
Publicado 2016

Translational readthrough of nonsense mutant TP53 by mRNA incorporation of 5-Fluorouridine

por Palomar-Siles, Mireia, Heldin, Angelos, Zhang, Meiqiongzi, Strandgren, Charlotte, Yurevych, Viktor, van Dinter, Jip T., Engels, Sem A. G., Hofman, Damon A., Öhlin, Susanne, Meineke, Birthe, Bykov, Vladimir J. N., van Heesch, Sebastiaan, Wiman, Klas G.
Publicado 2022