Complex peptide natural products: Biosynthetic principles, challenges and opportunities for pathway engineering

por Wenski, Sebastian L., Thiengmag, Sirinthra, Helfrich, Eric J.N.
Publicado 2022

Navigating and expanding the roadmap of natural product genome mining tools

por Biermann, Friederike, Wenski, Sebastian L, Helfrich, Eric J N
Publicado 2022

Bacterial terpene biosynthesis: challenges and opportunities for pathway engineering

por Helfrich, Eric J N, Lin, Geng-Min, Voigt, Christopher A, Clardy, Jon
Publicado 2019

A Polyketide Synthase Component for Oxygen Insertion into Polyketide Backbones

por Meoded, Roy A., Ueoka, Reiko, Helfrich, Eric J. N., Jensen, Katja, Magnus, Nancy, Piechulla, Birgit, Piel, Jörn
Publicado 2018

Pyonitrins A–D: Chimeric Natural Products Produced by Pseudomonas protegens

por Mevers, Emily, Saurí, Josep, Helfrich, Eric J. N., Henke, Matthew, Barns, Kenneth J., Bugni, Tim S., Andes, David, Currie, Cameron R., Clardy, Jon
Publicado 2019

Atropopeptides are a Novel Family of Ribosomally Synthesized and Posttranslationally Modified Peptides with a Complex Molecular Shape

por Nanudorn, Pakjira, Thiengmag, Sirinthra, Biermann, Friederike, Erkoc, Pelin, Dirnberger, Sabrina D., Phan, Thao N., Fürst, Robert, Ueoka, Reiko, Helfrich, Eric J. N.
Publicado 2022

In plaque-mass spectrometry imaging of a bloom-forming alga during viral infection reveals a metabolic shift towards odd-chain fatty acid lipids

por Schleyer, Guy, Shahaf, Nir, Ziv, Carmit, Dong, Yonghui, Meoded, Roy A., Helfrich, Eric J. N., Schatz, Daniella, Rosenwasser, Shilo, Rogachev, Ilana, Aharoni, Asaph, Piel, Jörn, Vardi, Assaf
Publicado 2019

Automated structure prediction of trans-acyltransferase polyketide synthase products

por Helfrich, Eric J. N., Ueoka, Reiko, Dolev, Alon, Rust, Michael, Meoded, Roy A., Bhushan, Agneya, Califano, Gianmaria, Costa, Rodrigo, Gugger, Muriel, Steinbeck, Christoph, Moreno, Pablo, Piel, Jörn
Publicado 2019

Specialized Metabolites Reveal Evolutionary History and Geographic Dispersion of a Multilateral Symbiosis

por Fukuda, Taise T. H., Helfrich, Eric J. N., Mevers, Emily, Melo, Weilan G. P., Van Arnam, Ethan B., Andes, David R., Currie, Cameron R., Pupo, Monica T., Clardy, Jon
Publicado 2021

A multiproducer microbiome generates chemical diversity in the marine sponge Mycale hentscheli

por Rust, Michael, Helfrich, Eric J. N., Freeman, Michael F., Nanudorn, Pakjira, Field, Christopher M., Rückert, Christian, Kündig, Tomas, Page, Michael J., Webb, Victoria L., Kalinowski, Jörn, Sunagawa, Shinichi, Piel, Jörn
Publicado 2020

Evolution of combinatorial diversity in trans-acyltransferase polyketide synthase assembly lines across bacteria

por Helfrich, Eric J. N., Ueoka, Reiko, Chevrette, Marc G., Hemmerling, Franziska, Lu, Xiaowen, Leopold-Messer, Stefan, Minas, Hannah A., Burch, Adrien Y., Lindow, Steven E., Piel, Jörn, Medema, Marnix H.
Publicado 2021

Bacillimidazoles A−F, Imidazolium-Containing Compounds Isolated from a Marine Bacillus

por Yan, Jia-Xuan, Wu, Qihao, Helfrich, Eric J. N., Chevrette, Marc G., Braun, Doug R., Heyman, Heino, Ananiev, Gene E., Rajski, Scott R., Currie, Cameron R., Clardy, Jon, Bugni, Tim S.
Publicado 2022

antiSMASH 7.0: new and improved predictions for detection, regulation, chemical structures and visualisation

por Blin, Kai, Shaw, Simon, Augustijn, Hannah E, Reitz, Zachary L, Biermann, Friederike, Alanjary, Mohammad, Fetter, Artem, Terlouw, Barbara R, Metcalf, William W, Helfrich, Eric J N, van Wezel, Gilles P, Medema, Marnix H, Weber, Tilmann
Publicado 2023

MIBiG 3.0: a community-driven effort to annotate experimentally validated biosynthetic gene clusters

por Terlouw, Barbara R, Blin, Kai, Navarro-Muñoz, Jorge C, Avalon, Nicole E, Chevrette, Marc G, Egbert, Susan, Lee, Sanghoon, Meijer, David, Recchia, Michael J J, Reitz, Zachary L, van Santen, Jeffrey A, Selem-Mojica, Nelly, Tørring, Thomas, Zaroubi, Liana, Alanjary, Mohammad, Aleti, Gajender, Aguilar, César, Al-Salihi, Suhad A A, Augustijn, Hannah E, Avelar-Rivas, J Abraham, Avitia-Domínguez, Luis A, Barona-Gómez, Francisco, Bernaldo-Agüero, Jordan, Bielinski, Vincent A, Biermann, Friederike, Booth, Thomas J, Carrion Bravo, Victor J, Castelo-Branco, Raquel, Chagas, Fernanda O, Cruz-Morales, Pablo, Du, Chao, Duncan, Katherine R, Gavriilidou, Athina, Gayrard, Damien, Gutiérrez-García, Karina, Haslinger, Kristina, Helfrich, Eric J N, van der Hooft, Justin J J, Jati, Afif P, Kalkreuter, Edward, Kalyvas, Nikolaos, Kang, Kyo Bin, Kautsar, Satria, Kim, Wonyong, Kunjapur, Aditya M, Li, Yong-Xin, Lin, Geng-Min, Loureiro, Catarina, Louwen, Joris J R, Louwen, Nico L L, Lund, George, Parra, Jonathan, Philmus, Benjamin, Pourmohsenin, Bita, Pronk, Lotte J U, Rego, Adriana, Rex, Devasahayam Arokia Balaya, Robinson, Serina, Rosas-Becerra, L Rodrigo, Roxborough, Eve T, Schorn, Michelle A, Scobie, Darren J, Singh, Kumar Saurabh, Sokolova, Nika, Tang, Xiaoyu, Udwary, Daniel, Vigneshwari, Aruna, Vind, Kristiina, Vromans, Sophie P J M, Waschulin, Valentin, Williams, Sam E, Winter, Jaclyn M, Witte, Thomas E, Xie, Huali, Yang, Dong, Yu, Jingwei, Zdouc, Mitja, Zhong, Zheng, Collemare, Jérôme, Linington, Roger G, Weber, Tilmann, Medema, Marnix H
Publicado 2022

A community resource for paired genomic and metabolomic data mining

por Schorn, Michelle A., Verhoeven, Stefan, Ridder, Lars, Huber, Florian, Acharya, Deepa D., Aksenov, Alexander A., Aleti, Gajender, Moghaddam, Jamshid Amiri, Aron, Allegra T., Aziz, Saefuddin, Bauermeister, Anelize, Bauman, Katherine D., Baunach, Martin, Beemelmanns, Christine, Beman, J. Michael, Berlanga-Clavero, María Victoria, Blacutt, Alex A., Bode, Helge B., Boullie, Anne, Brejnrod, Asker, Bugni, Tim S., Calteau, Alexandra, Cao, Liu, Carrión, Víctor J., Castelo-Branco, Raquel, Chanana, Shaurya, Chase, Alexander B., Chevrette, Marc G., Costa-Lotufo, Leticia V., Crawford, Jason M., Currie, Cameron R., Cuypers, Bart, Dang, Tam, de Rond, Tristan, Demko, Alyssa M., Dittmann, Elke, Du, Chao, Drozd, Christopher, Dujardin, Jean-Claude, Dutton, Rachel J., Edlund, Anna, Fewer, David P., Garg, Neha, Gauglitz, Julia M., Gentry, Emily C., Gerwick, Lena, Glukhov, Evgenia, Gross, Harald, Gugger, Muriel, Guillén Matus, Dulce G., Helfrich, Eric J. N., Hempel, Benjamin-Florian, Hur, Jae-Seoun, Iorio, Marianna, Jensen, Paul R., Kang, Kyo Bin, Kaysser, Leonard, Kelleher, Neil L., Kim, Chung Sub, Kim, Ki Hyun, Koester, Irina, König, Gabriele M., Leao, Tiago, Lee, Seoung Rak, Lee, Yi-Yuan, Li, Xuanji, Little, Jessica C., Maloney, Katherine N., Männle, Daniel, Martin H., Christian, McAvoy, Andrew C., Metcalf, Willam W., Mohimani, Hosein, Molina-Santiago, Carlos, Moore, Bradley S., Mullowney, Michael W., Muskat, Mitchell, Nothias, Louis-Félix, O’Neill, Ellis C., Parkinson, Elizabeth I., Petras, Daniel, Piel, Jörn, Pierce, Emily C., Pires, Karine, Reher, Raphael, Romero, Diego, Roper, M. Caroline, Rust, Michael, Saad, Hamada, Saenz, Carmen, Sanchez, Laura M., Sørensen, Søren Johannes, Sosio, Margherita, Süssmuth, Roderich D., Sweeney, Douglas, Tahlan, Kapil, Thomson, Regan J., Tobias, Nicholas J., Trindade-Silva, Amaro E., van Wezel, Gilles P., Wang, Mingxun, Weldon, Kelly C., Zhang, Fan, Ziemert, Nadine, Duncan, Katherine R., Crüsemann, Max, Rogers, Simon, Dorrestein, Pieter C., Medema, Marnix H., van der Hooft, Justin J. J.
Publicado 2021