Mesolimbic opioid-dopamine interaction is disrupted in obesity but recovered by weight loss following bariatric surgery

por Karlsson, Henry K., Tuominen, Lauri, Helin, Semi, Salminen, Paulina, Nuutila, Pirjo, Nummenmaa, Lauri
Publicado 2021

Preoperative brain μ-opioid receptor availability predicts weight development following bariatric surgery in women

por Karlsson, Henry K., Tuominen, Lauri, Helin, Semi, Salminen, Paulina, Nuutila, Pirjo, Nummenmaa, Lauri
Publicado 2021

Insulin resistance and body mass index are associated with TSPO PET in cognitively unimpaired elderly

por Ekblad, Laura L, Tuisku, Jouni, Koivumäki, Mikko, Helin, Semi, Rinne, Juha O, Snellman, Anniina
Publicado 2023

Association of neuroinflammation with episodic memory: a [(11)C]PBR28 PET study in cognitively discordant twin pairs

por Lindgren, Noora, Tuisku, Jouni, Vuoksimaa, Eero, Helin, Semi, Karrasch, Mira, Marjamäki, Päivi, Kaprio, Jaakko, Rinne, Juha O
Publicado 2020

Adenosine A(2A) receptor availability in patients with early- and moderate-stage Parkinson’s disease

por Waggan, Imran, Rissanen, Eero, Tuisku, Jouni, Joutsa, Juho, Helin, Semi, Parkkola, Riitta, Rinne, Juha O., Airas, Laura
Publicado 2022

Midlife insulin resistance, APOE genotype, and late-life brain amyloid accumulation

por Ekblad, Laura L., Johansson, Jarkko, Helin, Semi, Viitanen, Matti, Laine, Hanna, Puukka, Pauli, Jula, Antti, Rinne, Juha O.
Publicado 2018

Regulation of human brown adipose tissue by adenosine and A(2A) receptors – studies with [(15)O]H(2)O and [(11)C]TMSX PET/CT

por Lahesmaa, Minna, Oikonen, Vesa, Helin, Semi, Luoto, Pauliina, U Din, Mueez, Pfeifer, Alexander, Nuutila, Pirjo, Virtanen, Kirsi A.
Publicado 2018

Endogenous Opioid Release After Orgasm in Man: A Combined PET/Functional MRI Study

por Jern, Patrick, Chen, Jinglu, Tuisku, Jouni, Saanijoki, Tiina, Hirvonen, Jussi, Lukkarinen, Lasse, Manninen, Sandra, Helin, Semi, Putkinen, Vesa, Nummenmaa, Lauri
Publicado 2023

(68)Ga-DOTA chelate, a novel imaging agent for assessment of myocardial perfusion and infarction detection in a rodent model

por Autio, Anu, Uotila, Sauli, Kiugel, Max, Kytö, Ville, Liljenbäck, Heidi, Kudomi, Nobuyuki, Oikonen, Vesa, Metsälä, Olli, Helin, Semi, Knuuti, Juhani, Saraste, Antti, Roivainen, Anne
Publicado 2019

Direct Comparison of [(18)F]F-DPA with [(18)F]DPA-714 and [(11)C]PBR28 for Neuroinflammation Imaging in the same Alzheimer’s Disease Model Mice and Healthy Controls

por López-Picón, Francisco R., Keller, Thomas, Bocancea, Diana, Helin, Jatta S., Krzyczmonik, Anna, Helin, Semi, Damont, Annelaure, Dollé, Frédéric, Rinne, Juha O., Haaparanta-Solin, Merja, Solin, Olof
Publicado 2021

Midlife Insulin Resistance as a Predictor for Late-Life Cognitive Function and Cerebrovascular Lesions

por Toppala, Sini, Ekblad, Laura L., Lötjönen, Jyrki, Helin, Semi, Hurme, Saija, Johansson, Jarkko, Jula, Antti, Karrasch, Mira, Koikkalainen, Juha, Laine, Hanna, Parkkola, Riitta, Viitanen, Matti, Rinne, Juha O.
Publicado 2019

Association of Early β-Amyloid Accumulation and Neuroinflammation Measured With [(11)C]PBR28 in Elderly Individuals Without Dementia

por Toppala, Sini, Ekblad, Laura L., Tuisku, Jouni, Helin, Semi, Johansson, Jarkko J., Laine, Hanna, Löyttyniemi, Eliisa, Marjamäki, Päivi, Blennow, Kaj, Zetterberg, Henrik, Jula, Antti, Viitanen, Matti, Rinne, Juha O.
Publicado 2021

Comparison of: (2S,4R)-4-[(18)F]Fluoroglutamine, [(11)C]Methionine, and 2-Deoxy-2-[(18)F]Fluoro-D-Glucose and Two Small-Animal PET/CT Systems Imaging Rat Gliomas

por Miner, Maxwell W. G., Liljenbäck, Heidi, Virta, Jenni, Helin, Semi, Eskola, Olli, Elo, Petri, Teuho, Jarmo, Seppälä, Kerttu, Oikonen, Vesa, Yang, Guangli, Kindler-Röhrborn, Andrea, Minn, Heikki, Li, Xiang-Guo, Roivainen, Anne
Publicado 2021

Folate receptor-targeted positron emission tomography of experimental autoimmune encephalomyelitis in rats

por Elo, Petri, Li, Xiang-Guo, Liljenbäck, Heidi, Helin, Semi, Teuho, Jarmo, Koskensalo, Kalle, Saunavaara, Virva, Marjamäki, Päivi, Oikonen, Vesa, Virta, Jenni, Chen, Qingshou, Low, Philip S., Knuuti, Juhani, Jalkanen, Sirpa, Airas, Laura, Roivainen, Anne
Publicado 2019

APOE ε4 gene dose effect on imaging and blood biomarkers of neuroinflammation and beta-amyloid in cognitively unimpaired elderly

por Snellman, Anniina, Ekblad, Laura L., Tuisku, Jouni, Koivumäki, Mikko, Ashton, Nicholas J., Lantero-Rodriguez, Juan, Karikari, Thomas K., Helin, Semi, Bucci, Marco, Löyttyniemi, Eliisa, Parkkola, Riitta, Karrasch, Mira, Schöll, Michael, Zetterberg, Henrik, Blennow, Kaj, Rinne, Juha O.
Publicado 2023

Obesity risk is associated with altered cerebral glucose metabolism and decreased μ-opioid and CB(1) receptor availability

por Kantonen, Tatu, Pekkarinen, Laura, Karjalainen, Tomi, Bucci, Marco, Kalliokoski, Kari, Haaparanta-Solin, Merja, Aarnio, Richard, Dickens, Alex M., von Eyken, Annie, Laitinen, Kirsi, Houttu, Noora, Kirjavainen, Anna K., Helin, Semi, Hirvonen, Jussi, Rönnemaa, Tapani, Nuutila, Pirjo, Nummenmaa, Lauri
Publicado 2021

[(11)C]carfentanil PET imaging for studying the peripheral opioid system in vivo: effect of photoperiod on mu-opioid receptor availability in brown adipose tissue

por Sun, Lihua, Aarnio, Richard, Herre, Erika Atencio, Kärnä, Salli, Palani, Senthil, Virtanen, Helena, Liljenbäck, Heidi, Virta, Jenni, Honkaniemi, Aake, Oikonen, Vesa, Han, Chunlei, Laurila, Sanna, Bucci, Marco, Helin, Semi, Yatkin, Emrah, Nummenmaa, Lauri, Nuutila, Pirjo, Tang, Jing, Roivainen, Anne
Publicado 2022

Seasonal Variation in the Brain μ-Opioid Receptor Availability

por Sun, Lihua, Tang, Jing, Liljenbäck, Heidi, Honkaniemi, Aake, Virta, Jenni, Isojärvi, Janne, Karjalainen, Tomi, Kantonen, Tatu, Nuutila, Pirjo, Hietala, Jarmo, Kaasinen, Valtteri, Kalliokoski, Kari, Hirvonen, Jussi, Scheinin, Harry, Helin, Semi, Eerola, Kim, Savontaus, Eriika, Yatkin, Emrah, Rinne, Juha O., Roivainen, Anne, Nummenmaa, Lauri
Publicado 2021

Elevated serum chemokine CCL22 levels in first-episode psychosis: associations with symptoms, peripheral immune state and in vivo brain glial cell function

por Laurikainen, Heikki, Vuorela, Arja, Toivonen, Anna, Reinert-Hartwall, Linnea, Trontti, Kalevi, Lindgren, Maija, Keinänen, Jaakko, Mäntylä, Teemu, Paju, Janina, Ilonen, Tuula, Armio, Reetta-Liina, Walta, Maija, Tuisku, Jouni, Helin, Semi, Marjamäki, Päivi, Hovatta, Iiris, Therman, Sebastian, Vaarala, Outi, Linnaranta, Outi, Kieseppä, Tuula, Salokangas, Raimo K. R., Honkanen, Jarno, Hietala, Jarmo, Suvisaari, Jaana
Publicado 2020

Effects of age, BMI and sex on the glial cell marker TSPO — a multicentre [(11)C]PBR28 HRRT PET study

por Tuisku, Jouni, Plavén-Sigray, Pontus, Gaiser, Edward C., Airas, Laura, Al-Abdulrasul, Haidar, Brück, Anna, Carson, Richard E., Chen, Ming-Kai, Cosgrove, Kelly P., Ekblad, Laura, Esterlis, Irina, Farde, Lars, Forsberg, Anton, Halldin, Christer, Helin, Semi, Kosek, Eva, Lekander, Mats, Lindgren, Noora, Marjamäki, Päivi, Rissanen, Eero, Sucksdorff, Marcus, Varrone, Andrea, Collste, Karin, Gallezot, Jean-Dominique, Hillmer, Ansel, Huang, Yiyun, Höglund, Caroline O., Johansson, Jarkko, Jucaite, Aurelija, Lampa, Jon, Nabulsi, Nabeel, Pittman, Brian, Sandiego, Christine M., Stenkrona, Per, Rinne, Juha, Matuskey, David, Cervenka, Simon
Publicado 2019