Transcription-associated recombination is independent of XRCC2 and mechanistically separate from homology-directed DNA double-strand break repair

por Savolainen, Linda, Helleday, Thomas
Publicado 2009

Inhibition of poly (ADP-ribose) polymerase activates ATM which is required for subsequent homologous recombination repair

por Bryant, Helen E., Helleday, Thomas
Publicado 2006

Strategies for the Use of Poly(adenosine diphosphate ribose) Polymerase (PARP) Inhibitors in Cancer Therapy

por Ström, Cecilia E., Helleday, Thomas
Publicado 2012

Targeting the DNA damage response and repair in cancer through nucleotide metabolism

por Helleday, Thomas, Rudd, Sean G.
Publicado 2022

Synthetic switches of OGG1 control initiation of base excision repair and offer new treatment strategies

por Benitéz‐Buelga, Carlos, Helleday, Thomas, Michel, Maurice
Publicado 2022

Transcription Inhibition by DRB Potentiates Recombinational Repair of UV Lesions in Mammalian Cells

por Stoimenov, Ivaylo, Schultz, Niklas, Gottipati, Ponnari, Helleday, Thomas
Publicado 2011

PathwAX: a web server for network crosstalk based pathway annotation

por Ogris, Christoph, Helleday, Thomas, Sonnhammer, Erik L.L.
Publicado 2016

OGG1 Inhibitor TH5487 Alters OGG1 Chromatin Dynamics and Prevents Incisions

por Hanna, Bishoy M. F., Helleday, Thomas, Mortusewicz, Oliver
Publicado 2020

The ERCC1/XPF endonuclease is required for efficient single-strand annealing and gene conversion in mammalian cells

por Al-Minawi, Ali Z., Saleh-Gohari, Nasrollah, Helleday, Thomas
Publicado 2008

The spliceosome U2 snRNP factors promote genome stability through distinct mechanisms; transcription of repair factors and R-loop processing

por Tanikawa, M, Sanjiv, K, Helleday, T, Herr, P, Mortusewicz, O
Publicado 2016

Managing COVID-19 in the oncology clinic and avoiding the distraction effect

por Cortiula, F., Pettke, A., Bartoletti, M., Puglisi, F., Helleday, T.
Publicado 2020

UV stalled replication forks restart by re-priming in human fibroblasts

por Elvers, Ingegerd, Johansson, Fredrik, Groth, Petra, Erixon, Klaus, Helleday, Thomas
Publicado 2011

A novel method for crosstalk analysis of biological networks: improving accuracy of pathway annotation

por Ogris, Christoph, Guala, Dimitri, Helleday, Thomas, Sonnhammer, Erik L. L.
Publicado 2017

MetaCNV - a consensus approach to infer accurate copy numbers from low coverage data

por Friedrich, Stefanie, Barbulescu, Remus, Helleday, Thomas, Sonnhammer, Erik L. L.
Publicado 2020

NEIL1 and NEIL2 Are Recruited as Potential Backup for OGG1 upon OGG1 Depletion or Inhibition by TH5487

por Hanna, Bishoy M. F., Michel, Maurice, Helleday, Thomas, Mortusewicz, Oliver
Publicado 2021

BRCA2-dependent homologous recombination is required for repair of Arsenite-induced replication lesions in mammalian cells

por Ying, Songmin, Myers, Katie, Bottomley, Sarah, Helleday, Thomas, Bryant, Helen E.
Publicado 2009

Radiotherapy fraction size sensitivity is modulated by DNA repair systems

por Somaiah, N, Yarnold, J, Daley, F, Pearson, A, Rothkamm, K, Helleday, T
Publicado 2010

Hydroxyurea-Stalled Replication Forks Become Progressively Inactivated and Require Two Different RAD51-Mediated Pathways for Restart and Repair

por Petermann, Eva, Orta, Manuel Luís, Issaeva, Natalia, Schultz, Niklas, Helleday, Thomas
Publicado 2010

E2F-7 couples DNA damage-dependent transcription with the DNA repair process

por Zalmas, Lykourgos-Panagiotis, Coutts, Amanda S, Helleday, Thomas, La Thangue, Nicholas B
Publicado 2013

Overexpression of the scaffold WD40 protein WRAP53β enhances the repair of and cell survival from DNA double-strand breaks

por Rassoolzadeh, H, Böhm, S, Hedström, E, Gad, H, Helleday, T, Henriksson, S, Farnebo, M
Publicado 2016