Viral proteases as targets for chemotherapeutic intervention

por Hellen, Christopher U.T., Wimmer, Eckard
Publicado 1992

Attachment of ribosomal complexes and retrograde scanning during initiation on the Halastavi árva virus IRES

por Abaeva, Irina S., Pestova, Tatyana V., Hellen, Christopher U.T.
Publicado 2016

Initiation on the divergent Type I cadicivirus IRES: factor requirements and interactions with the translation apparatus

por Asnani, Mukta, Pestova, Tatyana V., Hellen, Christopher U.T.
Publicado 2016

Toward the mechanism of eIF4F-mediated ribosomal attachment to mammalian capped mRNAs

por Kumar, Parimal, Hellen, Christopher U.T., Pestova, Tatyana V.
Publicado 2016

PCBP2 enables the cadicivirus IRES to exploit the function of a conserved GRNA tetraloop to enhance ribosomal initiation complex formation

por Asnani, Mukta, Pestova, Tatyana V., Hellen, Christopher U.T.
Publicado 2016

Two classes of EF1-family translational GTPases encoded by giant viruses

por Zinoviev, Alexandra, Kuroha, Kazushige, Pestova, Tatyana V, Hellen, Christopher U T
Publicado 2019

Horizontal gene transfer as a mechanism for the promiscuous acquisition of distinct classes of IRES by avian caliciviruses

por Arhab, Yani, Miścicka, Anna, Pestova, Tatyana V, Hellen, Christopher U T
Publicado 2021

Dissemination of Internal Ribosomal Entry Sites (IRES) Between Viruses by Horizontal Gene Transfer

por Arhab, Yani, Bulakhov, Alexander G., Pestova, Tatyana V., Hellen, Christopher U.T.
Publicado 2020

In vitro reconstitution of SARS CoV-2 Nsp1-induced mRNA cleavage reveals the key roles of the N-terminal domain of Nsp1 and the RRM domain of eIF3g

por Abaeva, Irina S., Arhab, Yani, Miścicka, Anna, Hellen, Christopher U. T., Pestova, Tatyana V.
Publicado 2023

Common conformational changes induced in type 2 picornavirus IRESs by cognate trans-acting factors

por Yu, Yingpu, Abaeva, Irina S., Marintchev, Assen, Pestova, Tatyana V., Hellen, Christopher U. T.
Publicado 2011

A translation enhancer element from black beetle virus engages yeast eIF4G1 to drive cap-independent translation initiation

por Trainor, Brandon M., Ghosh, Arnab, Pestov, Dimitri G., Hellen, Christopher U. T., Shcherbik, Natalia
Publicado 2021

Functional role and ribosomal position of the unique N-terminal region of DHX29, a factor required for initiation on structured mammalian mRNAs

por Sweeney, Trevor R, Dhote, Vidya, Guca, Ewelina, Hellen, Christopher U T, Hashem, Yaser, Pestova, Tatyana V
Publicado 2021

Dendritic BC1 RNA in translational control mechanisms

por Wang, Huidong, Iacoangeli, Anna, Lin, Daisy, Williams, Keith, Denman, Robert B., Hellen, Christopher U.T., Tiedge, Henri
Publicado 2005

Título no disponible

por Wang, Huidong, Iacoangeli, Anna, Lin, Daisy, Williams, Keith, Denman, Robert B., Hellen, Christopher U.T., Tiedge, Henri
Publicado 2006

Inhibition of translation by IFIT family members is determined by their ability to interact selectively with the 5′-terminal regions of cap0-, cap1- and 5′ppp- mRNAs

por Kumar, Parimal, Sweeney, Trevor R., Skabkin, Maxim A., Skabkina, Olga V., Hellen, Christopher U. T., Pestova, Tatyana V.
Publicado 2014

The structure and mechanism of action of a distinct class of dicistrovirus intergenic region IRESs

por Abaeva, Irina S, Young, Christina, Warsaba, Reid, Khan, Nadiyah, Tran, Lan Vy, Jan, Eric, Pestova, Tatyana V, Hellen, Christopher U T
Publicado 2023

Structure of the mammalian ribosomal pre-termination complex associated with eRF1•eRF3•GDPNP

por des Georges, Amédée, Hashem, Yaser, Unbehaun, Anett, Grassucci, Robert A., Taylor, Derek, Hellen, Christopher U. T., Pestova, Tatyana V., Frank, Joachim
Publicado 2014

Functions of unconventional mammalian translational GTPases GTPBP1 and GTPBP2

por Zinoviev, Alexandra, Goyal, Akanksha, Jindal, Supriya, LaCava, John, Komar, Anton A., Rodnina, Marina V., Hellen, Christopher U.T., Pestova, Tatyana V.
Publicado 2018

Position of eukaryotic translation initiation factor eIF1A on the 40S ribosomal subunit mapped by directed hydroxyl radical probing

por Yu, Yingpu, Marintchev, Assen, Kolupaeva, Victoria G., Unbehaun, Anett, Veryasova, Tatyana, Lai, Shao-Chiang, Hong, Peng, Wagner, Gerhard, Hellen, Christopher U. T., Pestova, Tatyana V.
Publicado 2009