New Horizons: Novel Adrenal Regenerative Therapies

por Bornstein, Stefan R, Malyukov, Maria, Heller, Carolin, Ziegler, Christian G, Ruiz-Babot, Gerard, Schedl, Andreas, Ludwig, Barbara, Steenblock, Charlotte
Publicado 2020

CSF synaptic protein concentrations are raised in those with atypical Alzheimer’s disease but not frontotemporal dementia

por Clarke, Mica T. M., Brinkmalm, Ann, Foiani, Martha S., Woollacott, Ione O. C., Heller, Carolin, Heslegrave, Amanda, Keshavan, Ashvini, Fox, Nick C., Schott, Jonathan M., Warren, Jason D., Blennow, Kaj, Zetterberg, Henrik, Rohrer, Jonathan D.
Publicado 2019

Plasma tau is increased in frontotemporal dementia

por Foiani, Martha S, Woollacott, Ione OC, Heller, Carolin, Bocchetta, Martina, Heslegrave, Amanda, Dick, Katrina M, Russell, Lucy L, Marshall, Charles R, Mead, Simon, Schott, Jonathan M, Fox, Nick C, Warren, Jason D, Zetterberg, Henrik, Rohrer, Jonathan D
Publicado 2018

Cerebrospinal fluid soluble TREM2 levels in frontotemporal dementia differ by genetic and pathological subgroup

por Woollacott, Ione O. C., Nicholas, Jennifer M., Heslegrave, Amanda, Heller, Carolin, Foiani, Martha S., Dick, Katrina M., Russell, Lucy L., Paterson, Ross W., Keshavan, Ashvini, Fox, Nick C., Warren, Jason D., Schott, Jonathan M., Zetterberg, Henrik, Rohrer, Jonathan D.
Publicado 2018

Muscle and not neuronal biomarkers correlate with severity in spinal and bulbar muscular atrophy

por Lombardi, Vittoria, Querin, Giorgia, Ziff, Oliver J., Zampedri, Luca, Martinelli, Ilaria, Heller, Carolin, Foiani, Martha, Bertolin, Cinzia, Lu, Ching-Hua, Malik, Bilal, Allen, Kezia, Rinaldi, Carlo, Zetterberg, Henrik, Heslegrave, Amanda, Greensmith, Linda, Hanna, Michael, Soraru, Gianni, Malaspina, Andrea, Fratta, Pietro
Publicado 2019

Searching for novel cerebrospinal fluid biomarkers of tau pathology in frontotemporal dementia: an elusive quest

por Foiani, Martha S, Cicognola, Claudia, Ermann, Natalia, Woollacott, Ione O C, Heller, Carolin, Heslegrave, Amanda J, Keshavan, Ashvini, Paterson, Ross W, Ye, Keqiang, Kornhuber, Johannes, Fox, Nick C, Schott, Jonathan M, Warren, Jason D, Lewczuk, Piotr, Zetterberg, Henrik, Blennow, Kaj, Höglund, Kina, Rohrer, Jonathan D
Publicado 2019

Plasma Neurofilament Light as a Biomarker of Neurological Involvement in Wilson's Disease

por Shribman, Samuel, Heller, Carolin, Burrows, Maggie, Heslegrave, Amanda, Swift, Imogen, Foiani, Martha S., Gillett, Godfrey T., Tsochatzis, Emmanuel A., Rowe, James B., Gerhard, Alex, Butler, Chris R., Masellis, Mario, Bremner, Fion, Martin, Alison, Jung, Lynne, Cook, Paul, Zetterberg, Henrik, Bandmann, Oliver, Rohrer, Jonathan D., Warner, Thomas T.
Publicado 2020

Disease-related cortical thinning in presymptomatic granulin mutation carriers

por Borrego-Écija, Sergi, Sala-Llonch, Roser, van Swieten, John, Borroni, Barbara, Moreno, Fermín, Masellis, Mario, Tartaglia, Carmela, Graff, Caroline, Galimberti, Daniela, Laforce, Robert, Rowe, James B, Finger, Elizabeth, Vandenberghe, Rik, Tagliavini, Fabrizio, de Mendonça, Alexandre, Santana, Isabel, Synofzik, Matthis, Ducharme, Simon, Levin, Johannes, Danek, Adrian, Gerhard, Alex, Otto, Markus, Butler, Chris, Frisoni, Giovanni, Sorbi, Sandro, Heller, Carolin, Bocchetta, Martina, Cash, David M, Convery, Rhian S, Moore, Katrina M, Rohrer, Jonathan D, Sanchez-Valle, Raquel
Publicado 2020

Seed amplification and neurodegeneration marker trajectories in individuals at risk of prion disease

por Mok, Tze How, Nihat, Akin, Majbour, Nour, Sequeira, Danielle, Holm-Mercer, Leah, Coysh, Thomas, Darwent, Lee, Batchelor, Mark, Groveman, Bradley R, Orr, Christina D, Hughson, Andrew G, Heslegrave, Amanda, Laban, Rhiannon, Veleva, Elena, Paterson, Ross W, Keshavan, Ashvini, Schott, Jonathan M, Swift, Imogen J, Heller, Carolin, Rohrer, Jonathan D, Gerhard, Alexander, Butler, Christopher, Rowe, James B, Masellis, Mario, Chapman, Miles, Lunn, Michael P, Bieschke, Jan, Jackson, Graham S, Zetterberg, Henrik, Caughey, Byron, Rudge, Peter, Collinge, John, Mead, Simon
Publicado 2023

Altered plasma protein profiles in genetic FTD – a GENFI study

por Ullgren, Abbe, Öijerstedt, Linn, Olofsson, Jennie, Bergström, Sofia, Remnestål, Julia, van Swieten, John C., Jiskoot, Lize C., Seelaar, Harro, Borroni, Barbara, Sanchez-Valle, Raquel, Moreno, Fermin, Laforce, Robert, Synofzik, Matthis, Galimberti, Daniela, Rowe, James B., Masellis, Mario, Tartaglia, Maria Carmela, Finger, Elizabeth, Vandenberghe, Rik, de Mendonça, Alexandre, Tirabosch, Pietro, Santana, Isabel, Ducharme, Simon, Butler, Chris R., Gerhard, Alexander, Otto, Markus, Bouzigues, Arabella, Russell, Lucy, Swift, Imogen J., Sogorb-Esteve, Aitana, Heller, Carolin, Rohrer, Jonathan D., Månberg, Anna, Nilsson, Peter, Graff, Caroline
Publicado 2023

Analysis of brain atrophy and local gene expression in genetic frontotemporal dementia

por Altmann, Andre, Cash, David M, Bocchetta, Martina, Heller, Carolin, Reynolds, Regina, Moore, Katrina, Convery, Rhian S, Thomas, David L, van Swieten, John C, Moreno, Fermin, Sanchez-Valle, Raquel, Borroni, Barbara, Laforce, Robert, Masellis, Mario, Tartaglia, Maria Carmela, Graff, Caroline, Galimberti, Daniela, Rowe, James B, Finger, Elizabeth, Synofzik, Matthis, Vandenberghe, Rik, de Mendonça, Alexandre, Tagliavini, Fabrizio, Santana, Isabel, Ducharme, Simon, Butler, Chris R, Gerhard, Alex, Levin, Johannes, Danek, Adrian, Frisoni, Giovanni, Ghidoni, Roberta, Sorbi, Sandro, Otto, Markus, Ryten, Mina, Rohrer, Jonathan D
Publicado 2020

Differential impairment of cerebrospinal fluid synaptic biomarkers in the genetic forms of frontotemporal dementia

por Sogorb-Esteve, Aitana, Nilsson, Johanna, Swift, Imogen J., Heller, Carolin, Bocchetta, Martina, Russell, Lucy L., Peakman, Georgia, Convery, Rhian S., van Swieten, John C., Seelaar, Harro, Borroni, Barbara, Galimberti, Daniela, Sanchez-Valle, Raquel, Laforce, Robert, Moreno, Fermin, Synofzik, Matthis, Graff, Caroline, Masellis, Mario, Tartaglia, Maria Carmela, Rowe, James B., Vandenberghe, Rik, Finger, Elizabeth, Tagliavini, Fabrizio, Santana, Isabel, Butler, Chris R., Ducharme, Simon, Gerhard, Alexander, Danek, Adrian, Levin, Johannes, Otto, Markus, Sorbi, Sandro, Le Ber, Isabelle, Pasquier, Florence, Gobom, Johan, Brinkmalm, Ann, Blennow, Kaj, Zetterberg, Henrik, Rohrer, Jonathan D.
Publicado 2022

Apathy in presymptomatic genetic frontotemporal dementia predicts cognitive decline and is driven by structural brain changes

por Malpetti, Maura, Jones, P. Simon, Tsvetanov, Kamen A., Rittman, Timothy, van Swieten, John C., Borroni, Barbara, Sanchez‐Valle, Raquel, Moreno, Fermin, Laforce, Robert, Graff, Caroline, Synofzik, Matthis, Galimberti, Daniela, Masellis, Mario, Tartaglia, Maria Carmela, Finger, Elizabeth, Vandenberghe, Rik, de Mendonça, Alexandre, Tagliavini, Fabrizio, Santana, Isabel, Ducharme, Simon, Butler, Chris R., Gerhard, Alexander, Levin, Johannes, Danek, Adrian, Otto, Markus, Frisoni, Giovanni B., Ghidoni, Roberta, Sorbi, Sandro, Heller, Carolin, Todd, Emily G., Bocchetta, Martina, Cash, David M., Convery, Rhian S., Peakman, Georgia, Moore, Katrina M., Rohrer, Jonathan D., Kievit, Rogier A., Rowe, James B., (GENFI), Genetic FTD Initiative
Publicado 2020

Development of a sensitive trial-ready poly(GP) CSF biomarker assay for C9orf72-associated frontotemporal dementia and amyotrophic lateral sclerosis

por Wilson, Katherine M, Katona, Eszter, Glaria, Idoia, Carcolé, Mireia, Swift, Imogen J, Sogorb-Esteve, Aitana, Heller, Carolin, Bouzigues, Arabella, Heslegrave, Amanda J, Keshavan, Ashvini, Knowles, Kathryn, Patil, Saurabh, Mohapatra, Susovan, Liu, Yuanjing, Goyal, Jaya, Sanchez-Valle, Raquel, Laforce, Robert Jr, Synofzik, Matthis, Rowe, James B, Finger, Elizabeth, Vandenberghe, Rik, Butler, Christopher R, Gerhard, Alexander, Van Swieten, John C, Seelaar, Harro, Borroni, Barbara, Galimberti, Daniela, de Mendonça, Alexandre, Masellis, Mario, Tartaglia, M Carmela, Otto, Markus, Graff, Caroline, Ducharme, Simon, Schott, Jonathan M, Malaspina, Andrea, Zetterberg, Henrik, Boyanapalli, Ramakrishna, Rohrer, Jonathan D, Isaacs, Adrian M
Publicado 2022

CSF glial markers are elevated in a subset of patients with genetic frontotemporal dementia

por Woollacott, Ione O. C., Swift, Imogen J., Sogorb‐Esteve, Aitana, Heller, Carolin, Knowles, Kathryn, Bouzigues, Arabella, Russell, Lucy L., Peakman, Georgia, Greaves, Caroline V., Convery, Rhian, Heslegrave, Amanda, Rowe, James B., Borroni, Barbara, Galimberti, Daniela, Tiraboschi, Pietro, Masellis, Mario, Tartaglia, Maria Carmela, Finger, Elizabeth, van Swieten, John C., Seelaar, Harro, Jiskoot, Lize, Sorbi, Sandro, Butler, Chris R., Graff, Caroline, Gerhard, Alexander, Laforce, Robert, Sanchez‐Valle, Raquel, de Mendonça, Alexandre, Moreno, Fermin, Synofzik, Matthis, Vandenberghe, Rik, Ducharme, Simon, Ber, Isabelle Le, Levin, Johannes, Otto, Markus, Pasquier, Florence, Santana, Isabel, Zetterberg, Henrik, Rohrer, Jonathan D.
Publicado 2022

White matter hyperintensities in progranulin-associated frontotemporal dementia: A longitudinal GENFI study

por Sudre, Carole H., Bocchetta, Martina, Heller, Carolin, Convery, Rhian, Neason, Mollie, Moore, Katrina M., Cash, David M., Thomas, David L., Woollacott, Ione O.C., Foiani, Martha, Heslegrave, Amanda, Shafei, Rachelle, Greaves, Caroline, van Swieten, John, Moreno, Fermin, Sanchez-Valle, Raquel, Borroni, Barbara, Laforce, Robert, Masellis, Mario, Tartaglia, Maria Carmela, Graff, Caroline, Galimberti, Daniela, Rowe, James B., Finger, Elizabeth, Synofzik, Matthis, Vandenberghe, Rik, de Mendonça, Alexandre, Tagliavini, Fabrizio, Santana, Isabel, Ducharme, Simon, Butler, Chris, Gerhard, Alex, Levin, Johannes, Danek, Adrian, Frisoni, Giovanni B., Sorbi, Sandro, Otto, Markus, Zetterberg, Henrik, Ourselin, Sebastien, Cardoso, M. Jorge, Rohrer, Jonathan D.
Publicado 2019

Neuronal pentraxin 2: a synapse-derived CSF biomarker in genetic frontotemporal dementia

por van der Ende, Emma L, Xiao, Meifang, Xu, Desheng, Poos, Jackie M, Panman, Jessica L, Jiskoot, Lize C, Meeter, Lieke H, Dopper, Elise GP, Papma, Janne M, Heller, Carolin, Convery, Rhian, Moore, Katrina, Bocchetta, Martina, Neason, Mollie, Peakman, Georgia, Cash, David M, Teunissen, Charlotte E, Graff, Caroline, Synofzik, Matthis, Moreno, Fermin, Finger, Elizabeth, Sánchez-Valle, Raquel, Vandenberghe, Rik, Laforce Jr, Robert, Masellis, Mario, Tartaglia, Maria Carmela, Rowe, James B, Butler, Christopher R, Ducharme, Simon, Gerhard, Alex, Danek, Adrian, Levin, Johannes, Pijnenburg, Yolande AL, Otto, Markus, Borroni, Barbara, Tagliavini, Fabrizio, de Mendonca, Alexandre, Santana, Isabel, Galimberti, Daniela, Seelaar, Harro, Rohrer, Jonathan D, Worley, Paul F, van Swieten, John C
Publicado 2020

A data-driven disease progression model of fluid biomarkers in genetic frontotemporal dementia

por van der Ende, Emma L, Bron, Esther E, Poos, Jackie M, Jiskoot, Lize C, Panman, Jessica L, Papma, Janne M, Meeter, Lieke H, Dopper, Elise G P, Wilke, Carlo, Synofzik, Matthis, Heller, Carolin, Swift, Imogen J, Sogorb-Esteve, Aitana, Bouzigues, Arabella, Borroni, Barbara, Sanchez-Valle, Raquel, Moreno, Fermin, Graff, Caroline, Laforce, Robert, Galimberti, Daniela, Masellis, Mario, Tartaglia, Maria Carmela, Finger, Elizabeth, Vandenberghe, Rik, Rowe, James B, de Mendonça, Alexandre, Tagliavini, Fabrizio, Santana, Isabel, Ducharme, Simon, Butler, Christopher R, Gerhard, Alexander, Levin, Johannes, Danek, Adrian, Otto, Markus, Pijnenburg, Yolande A L, Sorbi, Sandro, Zetterberg, Henrik, Niessen, Wiro J, Rohrer, Jonathan D, Klein, Stefan, van Swieten, John C, Venkatraghavan, Vikram, Seelaar, Harro
Publicado 2021

Elevated CSF and plasma complement proteins in genetic frontotemporal dementia: results from the GENFI study

por van der Ende, Emma L., Heller, Carolin, Sogorb-Esteve, Aitana, Swift, Imogen J., McFall, David, Peakman, Georgia, Bouzigues, Arabella, Poos, Jackie M., Jiskoot, Lize C., Panman, Jessica L., Papma, Janne M., Meeter, Lieke H., Dopper, Elise G. P., Bocchetta, Martina, Todd, Emily, Cash, David, Graff, Caroline, Synofzik, Matthis, Moreno, Fermin, Finger, Elizabeth, Sanchez-Valle, Raquel, Vandenberghe, Rik, Laforce, Robert, Masellis, Mario, Tartaglia, Maria Carmela, Rowe, James B., Butler, Chris, Ducharme, Simon, Gerhard, Alexander, Danek, Adrian, Levin, Johannes, Pijnenburg, Yolande A. L., Otto, Markus, Borroni, Barbara, Tagliavini, Fabrizio, de Mendonça, Alexandre, Santana, Isabel, Galimberti, Daniela, Sorbi, Sandro, Zetterberg, Henrik, Huang, Eric, van Swieten, John C., Rohrer, Jonathan D., Seelaar, Harro
Publicado 2022

Plasma Neurofilament Light for Prediction of Disease Progression in Familial Frontotemporal Lobar Degeneration

por Rojas, Julio C., Wang, Ping, Staffaroni, Adam M., Heller, Carolin, Cobigo, Yann, Wolf, Amy, Goh, Sheng-Yang M., Ljubenkov, Peter A., Heuer, Hilary W., Fong, Jamie C., Taylor, Joanne B., Veras, Eliseo, Song, Linan, Jeromin, Andreas, Hanlon, David, Yu, Lili, Khinikar, Arvind, Sivasankaran, Rajeev, Kieloch, Agnieszka, Valentin, Marie-Anne, Karydas, Anna M., Mitic, Laura L., Pearlman, Rodney, Kornak, John, Kramer, Joel H., Miller, Bruce L., Kantarci, Kejal, Knopman, David S., Graff-Radford, Neill, Petrucelli, Leonard, Rademakers, Rosa, Irwin, David J., Grossman, Murray, Ramos, Eliana Marisa, Coppola, Giovanni, Mendez, Mario F., Bordelon, Yvette, Dickerson, Bradford C., Ghoshal, Nupur, Huey, Edward D., Mackenzie, Ian R., Appleby, Brian S., Domoto-Reilly, Kimiko, Hsiung, Ging-Yuek R., Toga, Arthur W., Weintraub, Sandra, Kaufer, Daniel I., Kerwin, Diana, Litvan, Irene, Onyike, Chiadikaobi U., Pantelyat, Alexander, Roberson, Erik D., Tartaglia, Maria C., Foroud, Tatiana, Chen, Weiping, Czerkowicz, Julie, Graham, Danielle L., van Swieten, John C., Borroni, Barbara, Sanchez-Valle, Raquel, Moreno, Fermin, Laforce, Robert, Graff, Caroline, Synofzik, Matthis, Galimberti, Daniela, Rowe, James B., Masellis, Mario, Finger, Elizabeth, Vandenberghe, Rik, de Mendonça, Alexandre, Tagliavini, Fabrizio, Santana, Isabel, Ducharme, Simon, Butler, Chris R., Gerhard, Alexander, Levin, Johannes, Danek, Adrian, Otto, Markus, Sorbi, Sandro, Cash, David M., Convery, Rhian S., Bocchetta, Martina, Foiani, Martha, Greaves, Caroline V., Peakman, Georgia, Russell, Lucy, Swift, Imogen, Todd, Emily, Rohrer, Jonathan D., Boeve, Bradley F., Rosen, Howard J., Boxer, Adam L.
Publicado 2021