The Delta Subunit of Rod-Specific Photoreceptor cGMP Phosphodiesterase (PDE6D) Contributes to Hepatocellular Carcinoma Progression

por Dietrich, Peter, Hellerbrand, Claus, Bosserhoff, Anja
Publicado 2019

The hop constituent xanthohumol exhibits hepatoprotective effects and inhibits the activation of hepatic stellate cells at different levels

por Weiskirchen, Ralf, Mahli, Abdo, Weiskirchen, Sabine, Hellerbrand, Claus
Publicado 2015

Lipid Accumulation in Host Cells Promotes SARS-CoV-2 Replication

por Seitz, Tatjana, Setz, Christian, Rauch, Pia, Schubert, Ulrich, Hellerbrand, Claus
Publicado 2023

Dissimilar Appearances Are Deceptive–Common microRNAs and Therapeutic Strategies in Liver Cancer and Melanoma

por Linck-Paulus, Lisa, Hellerbrand, Claus, Bosserhoff, Anja K., Dietrich, Peter
Publicado 2020

UVB radiation represses CYLD expression in melanocytes

por Kuphal, Silke, Schneider, Nadja, Massoumi, Ramin, Hellerbrand, Claus, Bosserhoff, Anja Katrin
Publicado 2017

Bone Morphogenetic Protein 13 Has Protumorigenic Effects on Hepatocellular Carcinoma Cells In Vitro

por Kersten, Vanessa, Seitz, Tatjana, Sommer, Judith, Thasler, Wolfgang E., Bosserhoff, Anja, Hellerbrand, Claus
Publicado 2023

Neuroblastoma RAS Viral Oncogene Homolog (NRAS) Is a Novel Prognostic Marker and Contributes to Sorafenib Resistance in Hepatocellular Carcinoma()

por Dietrich, Peter, Gaza, Anne, Wormser, Laura, Fritz, Valerie, Hellerbrand, Claus, Bosserhoff, Anja Katrin
Publicado 2019

Fibroblast Growth Factor 9 is expressed by activated hepatic stellate cells and promotes progression of hepatocellular carcinoma

por Seitz, Tatjana, Freese, Kim, Dietrich, Peter, Thasler, Wolfgang Erwin, Bosserhoff, Anja, Hellerbrand, Claus
Publicado 2020

Combined effects of PLK1 and RAS in hepatocellular carcinoma reveal rigosertib as promising novel therapeutic “dual-hit” option

por Dietrich, Peter, Freese, Kim, Mahli, Abdo, Thasler, Wolfgang Erwin, Hellerbrand, Claus, Bosserhoff, Anja Katrin
Publicado 2017

A Xanthohumol-Rich Hop Extract Diminishes Endotoxin-Induced Activation of TLR4 Signaling in Human Peripheral Blood Mononuclear Cells: A Study in Healthy Women

por Jung, Finn, Staltner, Raphaela, Baumann, Anja, Burger, Katharina, Halilbasic, Emina, Hellerbrand, Claus, Bergheim, Ina
Publicado 2022

Formation of Fenestrae in Murine Liver Sinusoids Depends on Plasmalemma Vesicle-Associated Protein and Is Required for Lipoprotein Passage

por Herrnberger, Leonie, Hennig, Robert, Kremer, Werner, Hellerbrand, Claus, Goepferich, Achim, Kalbitzer, Hans Robert, Tamm, Ernst R.
Publicado 2014

Role of mammalian target of rapamycin complex 2 in primary and secondary liver cancer

por Joechle, Katharina, Guenzle, Jessica, Hellerbrand, Claus, Strnad, Pavel, Cramer, Thorsten, Neumann, Ulf Peter, Lang, Sven Arke
Publicado 2021

Oral intake of xanthohumol attenuates lipoteichoic acid-induced inflammatory response in human PBMCs

por Jung, Finn, Staltner, Raphaela, Tahir, Ammar, Baumann, Anja, Burger, Katharina, Halilbasic, Emina, Hellerbrand, Claus, Bergheim, Ina
Publicado 2022

Therapeutic Application of Micellar Solubilized Xanthohumol in a Western-Type Diet-Induced Mouse Model of Obesity, Diabetes and Non-Alcoholic Fatty Liver Disease

por Mahli, Abdo, Seitz, Tatjana, Freese, Kim, Frank, Jan, Weiskirchen, Ralf, Abdel-Tawab, Mona, Behnam, Dariush, Hellerbrand, Claus
Publicado 2019

Histone Deacetylase Expressions in Hepatocellular Carcinoma and Functional Effects of Histone Deacetylase Inhibitors on Liver Cancer Cells In Vitro

por Freese, Kim, Seitz, Tatjana, Dietrich, Peter, Lee, Serene M.L., Thasler, Wolfgang E., Bosserhoff, Anja, Hellerbrand, Claus
Publicado 2019

Complex Formation with Monomeric α-Tubulin and Importin 13 Fosters c-Jun Protein Stability and Is Required for c-Jun’s Nuclear Translocation and Activity

por Kappelmann-Fenzl, Melanie, Kuphal, Silke, Krupar, Rosemarie, Schadendorf, Dirk, Umansky, Viktor, Vardimon, Lily, Hellerbrand, Claus, Bosserhoff, Anja-Katrin
Publicado 2019

Dual Inhibition of mTORC1/2 Reduces Migration of Cholangiocarcinoma Cells by Regulation of Matrixmetalloproteinases

por Joechle, Katharina, Jumaa, Huda, Thriene, Kerstin, Hellerbrand, Claus, Kulemann, Birte, Fichtner-Feigl, Stefan, Lang, Sven A., Guenzle, Jessica
Publicado 2022

Down-regulation of CYLD expression by Snail promotes tumor progression in malignant melanoma

por Massoumi, Ramin, Kuphal, Silke, Hellerbrand, Claus, Haas, Bodo, Wild, Peter, Spruss, Thilo, Pfeifer, Alexander, Fässler, Reinhard, Bosserhoff, Anja K.
Publicado 2009

ENMD-1198, a novel tubulin-binding agent reduces HIF-1alpha and STAT3 activity in human hepatocellular carcinoma(HCC) cells, and inhibits growth and vascularization in vivo

por Moser, Christian, Lang, Sven A, Mori, Akira, Hellerbrand, Claus, Schlitt, Hans J, Geissler, Edward K, Fogler, William E, Stoeltzing, Oliver
Publicado 2008

Pharmacological Inhibition of mTORC2 Reduces Migration and Metastasis in Melanoma

por Guenzle, Jessica, Akasaka, Harue, Joechle, Katharina, Reichardt, Wilfried, Venkatasamy, Aina, Hoeppner, Jens, Hellerbrand, Claus, Fichtner-Feigl, Stefan, Lang, Sven A.
Publicado 2020