Translating inspiration from COVID-19 vaccine trials to innovations in clinical cancer research

por Choudhury, Noura J., Riely, Gregory J., Sabbatini, Paul J., Hellmann, Matthew D.
Publicado 2021

Opportunistic infections in patients treated with immunotherapy for cancer

por Kyi, Chrisann, Hellmann, Matthew D, Wolchok, Jedd D, Chapman, Paul B, Postow, Michael A
Publicado 2014

Association Between the Early Discontinuation of Durvalumab and Poor Survival in Patients With Stage III NSCLC

por Shaverdian, Narek, Offin, Michael, Shepherd, Annemarie F., Hellmann, Matthew D., Gomez, Daniel R., Chaft, Jamie E., Rimner, Andreas
Publicado 2021

Acquired resistance to immunotherapy in MMR-D pancreatic cancer

por Hu, Zishuo Ian, Hellmann, Matthew D., Wolchok, Jedd D., Vyas, Monika, Shia, Jinru, Stadler, Zsofia K., Diaz, Luis A., O’Reilly, Eileen M.
Publicado 2018

Phase 1 study of epacadostat in combination with atezolizumab for patients with previously treated advanced nonsmall cell lung cancer

por Hellmann, Matthew D., Gettinger, Scott, Chow, Laura Q. M., Gordon, Michael, Awad, Mark M., Cha, Edward, Gong, Xiaohua, Zhou, Gongfu, Walker, Chris, Leopold, Lance, Heist, Rebecca S.
Publicado 2020

Expression of PD-L1 and other immunotherapeutic targets in thymic epithelial tumors

por Arbour, Kathryn C., Naidoo, Jarushka, Steele, Keith E., Ni, Ai, Moreira, Andre L., Rekhtman, Natasha, Robbins, Paul B., Karakunnel, Joyson, Rimner, Andreas, Huang, James, Riely, Gregory J., Hellmann, Matthew D.
Publicado 2017

Success and failure of additional immune modulators in steroid-refractory/resistant pneumonitis related to immune checkpoint blockade

por Beattie, Jason, Rizvi, Hira, Fuentes, Paige, Luo, Jia, Schoenfeld, Adam, Lin, I-Hsin, Postow, Michael, Callahan, Margaret, Voss, Martin H, Shah, Neil J, Betof Warner, Allison, Chawla, Mohit, Hellmann, Matthew D
Publicado 2021

Chromatin states define tumor-specific T cell dysfunction and reprogramming

por Philip, Mary, Fairchild, Lauren, Sun, Liping, Horste, Ellen L., Camara, Steven, Shakiba, Mojdeh, Scott, Andrew C., Viale, Agnes, Lauer, Peter, Merghoub, Taha, Hellmann, Matthew D., Wolchok, Jedd D., Leslie, Christina S., Schietinger, Andrea
Publicado 2017

30 Immunotherapy in advanced NSCLC—from the ‘tsunami’ of therapeutic knowledge to a clinical practice algorithm: results from an international expert panel meeting of the Italian A...

por de Marinis, Filippo, Ciardiello, Fortunato, Baas, Paul, Crinò, Lucio, Giaccone, Giuseppe, Grossi, Francesco, Hellmann, Matthew D, Mok, Tony S K, Lena, Hervè, Paz-Ares, Luis, Rodriguez-Abreu, Delvys, Von Pavel, Joachim, Gridelli, Cesare
Publicado 2018

Safety of combining thoracic radiation therapy with concurrent versus sequential immune checkpoint inhibition

por von Reibnitz, Donata, Chaft, Jamie E., Wu, Abraham J., Samstein, Robert, Hellmann, Matthew D., Plodkowski, Andrew J., Zhang, Zhigang, Shi, Weiji, Dick-Godfrey, Rosalind, Panchoo, Kelly H., Barker, Christopher A., Rimner, Andreas
Publicado 2018

Society for Immunotherapy of Cancer (SITC) consensus definitions for resistance to combinations of immune checkpoint inhibitors with chemotherapy

por Rizvi, Naiyer, Ademuyiwa, Foluso O, Cao, Z Alexander, Chen, Helen X, Ferris, Robert L, Goldberg, Sarah B, Hellmann, Matthew D, Mehra, Ranee, Rhee, Ina, Park, Jong Chul, Kluger, Harriet, Tawbi, Hussein, Sullivan, Ryan J
Publicado 2023

Targeting the differential addiction to anti-apoptotic BCL-2 family for cancer therapy

por Inoue-Yamauchi, Akane, Jeng, Paul S., Kim, Kwanghee, Chen, Hui-Chen, Han, Song, Ganesan, Yogesh Tengarai, Ishizawa, Kota, Jebiwott, Sylvia, Dong, Yiyu, Pietanza, Maria C., Hellmann, Matthew D., Kris, Mark G., Hsieh, James J., Cheng, Emily H.
Publicado 2017

Widespread hypertranscription in aggressive human cancers

por Zatzman, Matthew, Fuligni, Fabio, Ripsman, Ryan, Suwal, Tannu, Comitani, Federico, Edward, Lisa-Monique, Denroche, Rob, Jang, Gun Ho, Notta, Faiyaz, Gallinger, Steven, Selvanathan, Saravana P., Toretsky, Jeffrey A., Hellmann, Matthew D., Tabori, Uri, Huang, Annie, Shlien, Adam
Publicado 2022

Radiation pneumonitis in lung cancer patients treated with chemoradiation plus durvalumab

por Shaverdian, Narek, Thor, Maria, Shepherd, Annemarie F., Offin, Michael D., Jackson, Andrew, Wu, Abraham J., Gelblum, Daphna Y., Yorke, Ellen D., Simone, Charles B., Chaft, Jamie E., Hellmann, Matthew D., Gomez, Daniel R., Rimner, Andreas, Deasy, Joseph O.
Publicado 2020

Third-Line Nivolumab Monotherapy in Recurrent SCLC: CheckMate 032

por Ready, Neal, Farago, Anna F., de Braud, Filippo, Atmaca, Akin, Hellmann, Matthew D., Schneider, Jeffrey G., Spigel, David R., Moreno, Victor, Chau, Ian, Hann, Christine L., Eder, Joseph Paul, Steele, Nicola L., Pieters, Anne, Fairchild, Justin, Antonia, Scott J.
Publicado 2018

CD8-Targeted PET Imaging of Tumor-Infiltrating T Cells in Patients with Cancer: A Phase I First-in-Humans Study of (89)Zr-Df-IAB22M2C, a Radiolabeled Anti-CD8 Minibody

por Farwell, Michael D., Gamache, Raymond F., Babazada, Hasan, Hellmann, Matthew D., Harding, James J., Korn, Ron, Mascioni, Alessandro, Le, William, Wilson, Ian, Gordon, Michael S., Wu, Anna M., Ulaner, Gary A., Wolchok, Jedd D., Postow, Michael A., Pandit-Taskar, Neeta
Publicado 2022

Role of tumor infiltrating lymphocytes and spatial immune heterogeneity in sensitivity to PD-1 axis blockers in non-small cell lung cancer

por Lopez de Rodas, Miguel, Nagineni, Venkata, Ravi, Arvind, Datar, Ila J, Mino-Kenudson, Mari, Corredor, German, Barrera, Cristian, Behlman, Lindsey, Rimm, David L, Herbst, Roy S, Madabhushi, Anant, Riess, Jonathan W, Velcheti, Vamsidhar, Hellmann, Matthew D, Gainor, Justin, Schalper, Kurt A
Publicado 2022

Five-Year Overall Survival for Patients With Advanced Non‒Small-Cell Lung Cancer Treated With Pembrolizumab: Results From the Phase I KEYNOTE-001 Study

por Garon, Edward B., Hellmann, Matthew D., Rizvi, Naiyer A., Carcereny, Enric, Leighl, Natasha B., Ahn, Myung-Ju, Eder, Joseph Paul, Balmanoukian, Ani S., Aggarwal, Charu, Horn, Leora, Patnaik, Amita, Gubens, Matthew, Ramalingam, Suresh S., Felip, Enriqueta, Goldman, Jonathan W., Scalzo, Cathie, Jensen, Erin, Kush, Debra A., Hui, Rina
Publicado 2019

Escape from nonsense-mediated decay associates with anti-tumor immunogenicity

por Litchfield, Kevin, Reading, James L., Lim, Emilia L., Xu, Hang, Liu, Po, Al-Bakir, Maise, Wong, Yien Ning Sophia, Rowan, Andrew, Funt, Samuel A., Merghoub, Taha, Perkins, David, Lauss, Martin, Svane, Inge Marie, Jönsson, Göran, Herrero, Javier, Larkin, James, Quezada, Sergio A., Hellmann, Matthew D., Turajlic, Samra, Swanton, Charles
Publicado 2020

Contribution of systemic and somatic factors to clinical response and resistance to PD-L1 blockade in urothelial cancer: An exploratory multi-omic analysis

por Snyder, Alexandra, Nathanson, Tavi, Funt, Samuel A., Ahuja, Arun, Buros Novik, Jacqueline, Hellmann, Matthew D., Chang, Eliza, Aksoy, Bulent Arman, Al-Ahmadie, Hikmat, Yusko, Erik, Vignali, Marissa, Benzeno, Sharon, Boyd, Mariel, Moran, Meredith, Iyer, Gopa, Robins, Harlan S., Mardis, Elaine R., Merghoub, Taha, Hammerbacher, Jeff, Rosenberg, Jonathan E., Bajorin, Dean F.
Publicado 2017