You are what you eat: How to best fuel your immune system

por Hellmich, Charlotte, Wojtowicz, Edyta E.
Publicado 2022

ARQ531: the therapy that targets multiple pathways in acute myeloid leukemia

por Hellmich, Charlotte, Bowles, Kristian, Rushworth, Stuart
Publicado 2020

Acute Myeloid Leukaemia Drives Metabolic Changes in the Bone Marrow Niche

por Maynard, Rebecca S., Hellmich, Charlotte, Bowles, Kristian M., Rushworth, Stuart A.
Publicado 2022

Bone Marrow Senescence and the Microenvironment of Hematological Malignancies

por Hellmich, Charlotte, Moore, Jamie A., Bowles, Kristian M., Rushworth, Stuart A.
Publicado 2020

P1341: LC3-ASSOCIATED PHAGOCYTOSIS IS IMPAIRED IN BONE MARROW MACROPHAGES DURING AGEING LEADING TO DEFECTIVE PHAGOCYTOSIS AND ACCUMULATION OF APOPTOTIC DEBRIS WITHIN THE BONE MARRO...

por Hampton, Katherine, Hellmich, Charlotte, Maynard, Rebecca, Jibril, Aisha, Moore, Jamie, Bowles, Kristian, Rushworth, Stuart
Publicado 2023

P423: ACUTE MYELOID LEUKEMIA REPROGRAMS LIPID METABOLISM BY DOWNREGULATING CD36 EXPRESSION IN HEPATOCYTES.

por Maynard, Rebecca, Hampton, Katherine, Hellmich, Charlotte, Ehikioya, Martha, Fowler-Shorten, Dominic, Bowles, Kristian, Rushworth, Stuart
Publicado 2023

Genetics, sleep and memory: a recall-by-genotype study of ZNF804A variants and sleep neurophysiology

por Hellmich, Charlotte, Durant, Claire, Jones, Matthew W., Timpson, Nicholas J., Bartsch, Ullrich, Corbin, Laura J.
Publicado 2015

P469: ACUTE MYELOID LEUKEMIA DRIVES BCL-2 UPREGULATION IN NON MALIGNANT HSPCS WHICH IS TARGETED BY VENETOCLAX AND CAUSES CYTOPENIA

por Fowler-Shorten, Dominic, Maynard, Rebecca, Hampton, Katherine, Ehikioya, Martha, De Silva, Ravindu, Bowles, Kristian, Rushworth, Stuart, Hellmich, Charlotte
Publicado 2023

P856: MULTIPLE MYELOMA DERIVED IL-6 REDUCES FATTY ACID METABOLISM IN THE LIVER BY DOWNREGULATING CD36 AND CPT1A IN HEPATOCYTES

por Egheose Ehikioya, Martha, Maynard, Rebecca, Hampton, Katherine, Hellmich, Charlotte, De Silva, Ravindu, Fowler-Shorten, Dominic, Bowles, Kristian, Rushworth, Stuart
Publicado 2023

Venetoclax and Daratumumab combination treatment demonstrates pre-clinical efficacy in mouse models of Acute Myeloid Leukemia

por Mistry, Jayna J, Hellmich, Charlotte, Lambert, Amelia, Moore, Jamie A, Jibril, Aisha, Collins, Angela, Bowles, Kristian M, Rushworth, Stuart A
Publicado 2021

P431: ACTIVATION OF MACROPHAGE STING ENHANCES PHAGOCYTOSIS OF ACUTE MYELOID LEUKAEMIA

por Maynard, Rebecca, Hellmich, Charlotte, Hampton, Katherine, Moore, Jamie, Jibril, Aisha, De Silva, Ravindu, Fowler-Shorten, Dominic, Ehikioya, Martha, Bowles, Kristian, Rushworth, Stuart
Publicado 2023

Schizophrenia-associated variation at ZNF804A correlates with altered experience-dependent dynamics of sleep slow waves and spindles in healthy young adults

por Bartsch, Ullrich, Corbin, Laura J, Hellmich, Charlotte, Taylor, Michelle, Easey, Kayleigh E, Durant, Claire, Marston, Hugh M, Timpson, Nicholas J, Jones, Matthew W
Publicado 2021

Metabolic Regulation of Macrophages by SIRT1 Determines Activation During Cholestatic Liver Disease in Mice

por Isaacs-Ten, Anna, Moreno-Gonzalez, Mar, Bone, Caitlin, Martens, Andre, Bernuzzi, Federico, Ludwig, Tobias, Hellmich, Charlotte, Hiller, Karsten, Rushworth, Stuart A., Beraza, Naiara
Publicado 2021

Free fatty-acid transport via CD36 drives β-oxidation-mediated hematopoietic stem cell response to infection

por Mistry, Jayna J., Hellmich, Charlotte, Moore, Jamie A., Jibril, Aisha, Macaulay, Iain, Moreno-Gonzalez, Mar, Di Palma, Federica, Beraza, Naiara, Bowles, Kristian M., Rushworth, Stuart A.
Publicado 2021

PGC-1α induced mitochondrial biogenesis in stromal cells underpins mitochondrial transfer to melanoma

por Kumar, Prakrit R., Saad, Mona, Hellmich, Charlotte, Mistry, Jayna J., Moore, Jamie A., Conway, Shannon, Morris, Christopher J., Bowles, Kristian M., Moncrieff, Marc D., Rushworth, Stuart A.
Publicado 2022

p16INK4A-dependent senescence in the bone marrow niche drives age-related metabolic changes of hematopoietic progenitors

por Hellmich, Charlotte, Wojtowicz, Edyta, Moore, Jamie A., Mistry, Jayna J., Jibril, Aisha, Johnson, Benjamin B., Smith, James G. W., Beraza, Naiara, Bowles, Kristian M., Rushworth, Stuart A.
Publicado 2022

Daratumumab inhibits acute myeloid leukemia metabolic capacity by blocking mitochondrial transfer from mesenchymal stromal cells

por Mistry, Jayna J., Moore, Jamie A., Kumar, Prakrit, Marlein, Christopher R., Hellmich, Charlotte, Pillinger, Genevra, Jibril, Aisha, Di Palma, Federica, Collins, Angela, Bowles, Kristian M., Rushworth, Stuart A
Publicado 2020

Siglec-7 Mediates Immunomodulation by Colorectal Cancer-Associated Fusobacterium nucleatum ssp. animalis

por Lamprinaki, Dimitra, Garcia-Vello, Pilar, Marchetti, Roberta, Hellmich, Charlotte, McCord, Kelli A., Bowles, Kristian M., Macauley, Matthew S., Silipo, Alba, De Castro, Cristina, Crocker, Paul R., Juge, Nathalie
Publicado 2021

LC3-associated phagocytosis in bone marrow macrophages suppresses acute myeloid leukemia progression through STING activation

por Moore, Jamie A., Mistry, Jayna J., Hellmich, Charlotte, Horton, Rebecca H., Wojtowicz, Edyta E., Jibril, Aisha, Jefferson, Matthew, Wileman, Thomas, Beraza, Naiara, Bowles, Kristian M., Rushworth, Stuart A.
Publicado 2022

ROS-mediated PI3K activation drives mitochondrial transfer from stromal cells to hematopoietic stem cells in response to infection

por Mistry, Jayna J., Marlein, Christopher R., Moore, Jamie A., Hellmich, Charlotte, Wojtowicz, Edyta E., Smith, James G. W., Macaulay, Iain, Sun, Yu, Morfakis, Adam, Patterson, Angela, Horton, Rebecca H., Divekar, Devina, Morris, Christopher J., Haestier, Anna, Di Palma, Federica, Beraza, Naiara, Bowles, Kristian M., Rushworth, Stuart A.
Publicado 2019