Low Dose Histone Deacetylase Inhibitor, Depsipeptide (FR901228), Promotes Adenoviral Transduction in Human Rhabdomyosarcoma Cell Lines

por Navid, Fariba, Mischen, Blaine T., Helman, Lee J.
Publicado 2004

Disruption of the MyoD/p21 Pathway in Rhabdomyosarcoma

por Weintraub, Michael, Kalebic, Thea, Helman, Lee J., Bhatia, Kishor G.
Publicado 1997

IGF-1R Inhibition Activates a YES/SFK Bypass Resistance Pathway: Rational Basis for Co-Targeting IGF-1R and Yes/SFK Kinase in Rhabdomyosarcoma()

por Wan, Xiaolin, Yeung, Choh, Heske, Christine, Mendoza, Arnulfo, Helman, Lee J.
Publicado 2015

Glutamine synthetase is necessary for sarcoma adaptation to glutamine deprivation and tumor growth

por Issaq, Sameer H., Mendoza, Arnulfo, Fox, Stephen D., Helman, Lee J.
Publicado 2019

Molecular Alterations in Pediatric Sarcomas: Potential Targets for Immunotherapy

por Goletz, Theresa J., Mackall, Crystal L., Berzofsky, Jay A., Helman, Lee J.
Publicado 1998

Autocrine Transforming Growth Factor-β Growth Pathway in Murine Osteosarcoma Cell Lines Associated with Inability to Affect Phosphorylation of Retinoblastoma Protein

por Navid, Fariba, Letterio, John J., Yeung, Choh L., Pegtel, Michiel, Helman, Lee J.
Publicado 2000

The Role of PDGFR-β Activation in Acquired Resistance to IGF-1R Blockade in Preclinical Models of Rhabdomyosarcoma()

por Heske, Christine M., Yeung, Choh, Mendoza, Arnulfo, Baumgart, Joshua T., Edessa, Leah D., Wan, Xiaolin, Helman, Lee J.
Publicado 2016

Molecular mechanisms of Guadecitabine induced FGFR4 down regulation in alveolar rhabdomyosarcomas

por Darvishi, Emad, Slemmons, Katherine, Wan, Zesheng, Mitra, Sheetal, Hou, Xiaogang, Hugues Parmentier, Jean, Eddie Loh, Yong-Hwee, Helman, Lee J.
Publicado 2020

STA-8666, a novel HSP90 inhibitor/SN-38 drug conjugate, causes complete tumor regression in preclinical mouse models of pediatric sarcoma

por Heske, Christine M., Mendoza, Arnulfo, Edessa, Leah D., Baumgart, Joshua T., Lee, Sunmin, Trepel, Jane, Proia, David A., Neckers, Len, Helman, Lee J.
Publicado 2016

Upregulation of Glucose-Regulated Protein 78 in Metastatic Cancer Cells Is Necessary for Lung Metastasis Progression()()

por Lizardo, Michael M., Morrow, James J., Miller, Tyler E., Hong, Ellen S., Ren, Ling, Mendoza, Arnulfo, Halsey, Charles H., Scacheri, Peter C., Helman, Lee J., Khanna, Chand
Publicado 2016

SARC025 arms 1 and 2: A phase 1 study of the poly(ADP‐ribose) polymerase inhibitor niraparib with temozolomide or irinotecan in patients with advanced Ewing sarcoma

por Chugh, Rashmi, Ballman, Karla V., Helman, Lee J., Patel, Shreyaskumar, Whelan, Jeremy S., Widemann, Brigitte, Lu, Yao, Hawkins, Douglas S., Mascarenhas, Leo, Glod, John W., Ji, Jiuping, Zhang, Yiping, Reinke, Denise, Strauss, Sandra J.
Publicado 2020

Targeting Sporadic and Neurofibromatosis Type 1 (NF1) Related Refractory Malignant Peripheral Nerve Sheath Tumors (MPNST) in a Phase II Study of Everolimus in Combination with Beva...

por Widemann, Brigitte C., Lu, Yao, Reinke, Denise, Okuno, Scott H., Meyer, Christian F., Cote, Gregory M., Chugh, Rashmi, Milhem, Mohammed M., Hirbe, Angela C., Kim, AeRang, Turpin, Brian, Pressey, Joseph G., Dombi, Eva, Jayaprakash, Nalini, Helman, Lee J., Onwudiwe, Ndidi, Cichowski, Karen, Perentesis, John P.
Publicado 2019

SARC006: Phase II Trial of Chemotherapy in Sporadic and Neurofibromatosis Type 1 Associated Chemotherapy-Naive Malignant Peripheral Nerve Sheath Tumors

por Higham, Christine S., Steinberg, Seth M., Dombi, Eva, Perry, Arie, Helman, Lee J., Schuetze, Scott M., Ludwig, Joseph A., Staddon, Arthur, Milhem, Mohammed M., Rushing, Daniel, Jones, Robin L., Livingston, Michael, Goldman, Stewart, Moertel, Christopher, Wagner, Lars, Janhofer, David, Annunziata, Christina M., Reinke, Denise, Long, Lauren, Viskochil, David, Baker, Larry, Widemann, Brigitte C.
Publicado 2017

Positively selected enhancer elements endow osteosarcoma cells with metastatic competence

por Morrow, James J., Bayles, Ian, Funnell, Alister PW, Miller, Tyler E., Saiakhova, Alina, Lizardo, Michael M., Bartels, Cynthia F., Kapteijn, Maaike Y., Hung, Stevephen, Mendoza, Arnulfo, Dhillon, Gursimran, Chee, Daniel R., Myers, Jay T., Allen, Frederick, Gambarotti, Marco, Righi, Alberto, DiFeo, Analisa, Rubin, Brian P., Huang, Alex Y., Meltzer, Paul S., Helman, Lee J., Picci, Piero, Versteeg, Henri, Stamatoyannopolus, John, Khanna, Chand, Scacheri, Peter C.
Publicado 2018

The Childhood Cancer Data Initiative: Using the Power of Data to Learn From and Improve Outcomes for Every Child and Young Adult With Pediatric Cancer

por Flores-Toro, Joseph A., Jagu, Subhashini, Armstrong, Gregory T., Arons, David F., Aune, Gregory J., Chanock, Stephen J., Hawkins, Douglas S., Heath, Allison, Helman, Lee J., Janeway, Katherine A., Levine, Jason E., Miller, Ellyn, Penberthy, Lynne, Roberts, Charles W. M., Shalley, Eve R., Shern, Jack F., Smith, Malcolm A., Staudt, Louis M., Volchenboum, Samuel L., Zhang, Jinghui, Zenklusen, Jean Claude, Lowy, Douglas R., Sharpless, Norman E., Guidry Auvil, Jaime M., Kerlavage, Anthony R., Widemann, Brigitte C., Reaman, Gregory H., Kibbe, Warren A., Doroshow, James H.
Publicado 2023

The First European Interdisciplinary Ewing Sarcoma Research Summit

por Kovar, Heinrich, Alonso, Javier, Aman, Pierre, Aryee, Dave N. T., Ban, Jozef, Burchill, Sue A., Burdach, Stefan, De Alava, Enrique, Delattre, Olivier, Dirksen, Uta, Fourtouna, Argyro, Fulda, Simone, Helman, Lee J., Herrero-Martin, David, Hogendoorn, Pancras C. W., Kontny, Udo, Lawlor, Elizabeth R., Lessnick, Stephen L., Llombart-Bosch, Antonio, Metzler, Markus, Moriggl, Richard, Niedan, Stephan, Potratz, Jenny, Redini, Françoise, Richter, Günther H. S., Riedmann, Lucia T., Rossig, Claudia, Schäfer, Beat W., Schwentner, Raphaela, Scotlandi, Katia, Sorensen, Poul H., Staege, Martin S., Tirode, Franck, Toretsky, Jeffrey, Ventura, Selena, Eggert, Angelika, Ladenstein, Ruth
Publicado 2012