Episodic Myocarditis in Arrhythmogenic Cardiomyopathy: A Novel Treatment Target?

por Smith, Eric D., Helms, Adam
Publicado 2022

Translation of New and Emerging Therapies for Genetic Cardiomyopathies

por Helms, Adam S., Thompson, Andrea D., Day, Sharlene M.
Publicado 2021

Correlation of cardiac magnetic resonance imaging and electrophysiology study findings among patients with frequent premature ventricular contractions

por Helms, Adam, Prasitdumrong, Hutsaya, Agarwal, Prachi, Mueller, Gisela C, Bogun, Frank
Publicado 2012

Probabilistic integration of transcriptome-wide association studies and colocalization analysis identifies key molecular pathways of complex traits

por Okamoto, Jeffrey, Wang, Lijia, Yin, Xianyong, Luca, Francesca, Pique-Regi, Roger, Helms, Adam, Im, Hae Kyung, Morrison, Jean, Wen, Xiaoquan
Publicado 2023

Myofibrillar Structural Variability Underlies Contractile Function in Stem Cell-Derived Cardiomyocytes

por Ufford, Kathryn, Friedline, Sabrina, Tong, Zhaowen, Tang, Vi T., Dobbs, Amani S., Tsan, Yao-Chang, Bielas, Stephanie L., Liu, Allen P., Helms, Adam S.
Publicado 2021

An Unbiased Screen Identified the Hsp70-BAG3 Complex as a Regulator of Myosin-Binding Protein C3

por Thompson, Andrea D., Wagner, Marcus J., Rodriguez, Juliani, Malhotra, Alok, Vander Roest, Steve, Lilienthal, Ulla, Shao, Hao, Vignesh, Mathav, Weber, Keely, Yob, Jaime M., Prosser, Benjamin L., Helms, Adam S., Gestwicki, Jason E., Ginsburg, David, Day, Sharlene M.
Publicado 2023

Hypertrophic Cardiomyopathy With Left Ventricular Systolic Dysfunction: Insights From the SHaRe Registry

por Marstrand, Peter, Han, Larry, Day, Sharlene M., Olivotto, Iacopo, Ashley, Euan A., Michels, Michelle, Pereira, Alexandre C., Wittekind, Samuel G., Helms, Adam, Saberi, Sara, Jacoby, Daniel, Ware, James S., Colan, Steven D., Semsarian, Christopher, Ingles, Jodie, Lakdawala, Neal K., Ho, Carolyn Y.
Publicado 2020

Clinical characteristics and outcomes in childhood-onset hypertrophic cardiomyopathy

por Marston, Nicholas A, Han, Larry, Olivotto, Iacopo, Day, Sharlene M, Ashley, Euan A, Michels, Michelle, Pereira, Alexandre C, Ingles, Jodie, Semsarian, Christopher, Jacoby, Daniel, Colan, Steven D, Rossano, Joseph W, Wittekind, Samuel G, Ware, James S, Saberi, Sara, Helms, Adam S, Ho, Carolyn Y
Publicado 2021

Computational prediction of protein subdomain stability in MYBPC3 enables clinical risk stratification in hypertrophic cardiomyopathy and enhances variant interpretation

por Thompson, Andrea D., Helms, Adam S., Kannan, Anamika, Yob, Jaime, Lakdawala, Neal K., Wittekind, Samuel G., Pereira, Alexandre C., Jacoby, Daniel L., Colan, Steven D., Ashley, Euan A., Saberi, Sara, Ware, James S., Ingles, Jodie, Semsarian, Christopher, Michels, Michelle, Mazzarotto, Francesco, Olivotto, Iacopo, Ho, Carolyn Y., Day, Sharlene M.
Publicado 2021

Genotype and Lifetime Burden of Disease in Hypertrophic Cardiomyopathy: Insights From the Sarcomeric Human Cardiomyopathy Registry (SHaRe)

por Ho, Carolyn Y., Day, Sharlene M., Ashley, Euan A., Michels, Michelle, Pereira, Alexandre C., Jacoby, Daniel, Cirino, Allison L., Fox, Jonathan C., Lakdawala, Neal K., Ware, James S., Caleshu, Colleen A., Helms, Adam S., Colan, Steven D., Girolami, Francesca, Cecchi, Franco, Seidman, Christine E., Sajeev, Gautam, Signorovitch, James, Green, Eric M., Olivotto, Iacopo
Publicado 2018

Physiologic biomechanics enhance reproducible contractile development in a stem cell derived cardiac muscle platform

por Tsan, Yao-Chang, DePalma, Samuel J., Zhao, Yan-Ting, Capilnasiu, Adela, Wu, Yu-Wei, Elder, Brynn, Panse, Isabella, Ufford, Kathryn, Matera, Daniel L., Friedline, Sabrina, O’Leary, Thomas S., Wubshet, Nadab, Ho, Kenneth K. Y., Previs, Michael J., Nordsletten, David, Isom, Lori L., Baker, Brendon M., Liu, Allen P., Helms, Adam S.
Publicado 2021

Spatial and Functional Distribution of MYBPC3 Pathogenic Variants and Clinical Outcomes in Patients With Hypertrophic Cardiomyopathy

por Helms, Adam S., Thompson, Andrea D., Glazier, Amelia A., Hafeez, Neha, Kabani, Samat, Rodriguez, Juliani, Yob, Jaime M., Woolcock, Helen, Mazzarotto, Francesco, Lakdawala, Neal K., Wittekind, Samuel G., Pereira, Alexandre C., Jacoby, Daniel L., Colan, Steven D., Ashley, Euan A., Saberi, Sara, Ware, James S., Ingles, Jodie, Semsarian, Christopher, Michels, Michelle, Olivotto, Iacopo, Ho, Carolyn Y., Day, Sharlene M.
Publicado 2020

External validation of the HCM Risk-Kids model for predicting sudden cardiac death in childhood hypertrophic cardiomyopathy

por Norrish, Gabrielle, Qu, Chen, Field, Ella, Cervi, Elena, Khraiche, Diala, Klaassen, Sabine, Ojala, Tiina H, Sinagra, Gianfranco, Yamazawa, Hirokuni, Marrone, Chiara, Popoiu, Anca, Centeno, Fernando, Schouvey, Sylvie, Olivotto, Iacopo, Day, Sharlene M, Colan, Steve, Rossano, Joseph, Wittekind, Samuel G, Saberi, Sara, Russell, Mark, Helms, Adam, Ingles, Jodie, Semsarian, Christopher, Elliott, Perry M, Ho, Carolyn Y, Omar, Rumana Z, Kaski, Juan P
Publicado 2021

Left Ventricular Systolic Dysfunction in Patients Diagnosed With Hypertrophic Cardiomyopathy During Childhood: Insights From the SHaRe Registry

por Abou Alaiwi, Sarah, Roston, Thomas M., Marstrand, Peter, Claggett, Brian Lee, Parikh, Victoria N., Helms, Adam S., Ingles, Jodie, Lampert, Rachel, Lakdawala, Neal K., Michels, Michelle, Owens, Anjali T., Rossano, Joseph W., Saberi, Sara, Abrams, Dominic J., Ashley, Euan A., Semsarian, Christopher, Stendahl, John C., Ware, James S., Miller, Erin, Ryan, Thomas D., Russell, Mark W., Day, Sharlene M., Olivotto, Iacopo, Vissing, Christoffer R., Ho, Carolyn Y.
Publicado 2023

Impact of SARS‐Cov‐2 infection in patients with hypertrophic cardiomyopathy: results of an international multicentre registry

por Gimeno, Juan R., Olivotto, Iacopo, Rodríguez, Ana Isabel, Ho, Carolyn Y., Fernández, Adrián, Quiroga, Alejandro, Espinosa, Mari Angeles, Gómez‐González, Cristina, Robledo, María, Tojal‐Sierra, Lucas, Day, Sharlene M., Owens, Anjali, Barriales‐Villa, Roberto, Larrañaga, Jose María, Rodríguez‐Palomares, Jose, González‐del‐Hoyo, Maribel, Piqueras‐Flores, Jesús, Reza, Nosheen, Chumakova, Olga, Ashley, Euan A., Parikh, Victoria, Wheeler, Matthew, Jacoby, Daniel, Pereira, Alexandre C., Saberi, Sara, Helms, Adam S., Villacorta, Eduardo, Gallego‐Delgado, María, de Castro, Daniel, Domínguez, Fernando, Ripoll‐Vera, Tomás, Zorio‐Grima, Esther, Sánchez‐Martínez, José Carlos, García‐Álvarez, Ana, Arbelo, Elena, Mogollón, María Victoria, Fuentes‐Cañamero, María Eugenia, Grande, Elias, Peña, Carlos, Monserrat, Lorenzo, Lakdawala, Neal K.
Publicado 2022