Epigenetic impact of endocrine disrupting chemicals on lipid homeostasis and atherosclerosis: a pregnane X receptor-centric view

por Helsley, Robert N, Zhou, Changcheng
Publicado 2017

IKKβ links vascular inflammation to obesity and atherosclerosis

por Sui, Yipeng, Park, Se-Hyung, Xu, Jinxian, Monette, Sébastien, Helsley, Robert N., Han, Seong-Su, Zhou, Changcheng
Publicado 2014

Bisphenol A Increases Atherosclerosis in Pregnane X Receptor‐Humanized ApoE Deficient Mice

por Sui, Yipeng, Park, Se‐Hyung, Helsley, Robert N., Sunkara, Manjula, Gonzalez, Frank J., Morris, Andrew J., Zhou, Changcheng
Publicado 2014

IKKβ Is Essential for Adipocyte Survival and Adaptive Adipose Remodeling in Obesity

por Park, Se-Hyung, Liu, Zun, Sui, Yipeng, Helsley, Robert N., Zhu, Beibei, Powell, David K., Kern, Philip A., Zhou, Changcheng
Publicado 2016

A luminescence-based protocol for assessing fructose metabolism via quantification of ketohexokinase enzymatic activity in mouse or human hepatocytes

por Park, Se-Hyung, Helsley, Robert N., Noetzli, Leila, Tu, Ho-Chou, Wallenius, Kristina, O’Mahony, Gavin, Boucher, Jeremie, Liu, Jianming, Softic, Samir
Publicado 2021

HuR expression in adipose tissue mediates energy expenditure and acute thermogenesis independent of UCP1 expression

por Anthony, Sarah R., Guarnieri, Adrienne, Lanzillotta, Lindsey, Gozdiff, Anamarie, Green, Lisa C., O’Grady, Katherine, Helsley, Robert N., Owens, A. Phillip, Tranter, Michael
Publicado 2020

Efficacy of supermarket and web-based interventions for improving dietary quality: a randomized, controlled trial

por Steen, Dylan L., Helsley, Robert N., Bhatt, Deepak L., King, Eileen C., Summer, Suzanne S., Fenchel, Matthew, Saelens, Brian E., Eckman, Mark H., Couch, Sarah C.
Publicado 2022

Non-hematopoietic IL-4Rα expression contributes to fructose-driven obesity and metabolic sequelae

por Damen, Michelle S. M. A., Stankiewicz, Traci E., Park, Se-Hyung, Helsley, Robert N., Chan, Calvin C., Moreno-Fernandez, Maria E., Doll, Jessica R., Szabo, Sara, Herbert, De’Broski R., Softic, Samir, Divanovic, Senad
Publicado 2021

Loss of carnitine palmitoyltransferase 1a reduces docosahexaenoic acid-containing phospholipids and drives sexually dimorphic liver disease in mice

por Zelows, Mikala M., Cady, Corissa, Dharanipragada, Nikitha, Mead, Anna E., Kipp, Zachary A., Bates, Evelyn A., Varadharajan, Venkateshwari, Banerjee, Rakhee, Park, Se-Hyung, Shelman, Nathan R., Clarke, Harrison A., Hawkinson, Tara R., Medina, Terrymar, Sun, Ramon C., Lydic, Todd A., Hinds, Terry D., Brown, J. Mark, Softic, Samir, Graf, Gregory A., Helsley, Robert N.
Publicado 2023

Fructose Induced KHK-C Increases ER Stress and Modulates Hepatic Transcriptome to Drive Liver Disease in Diet-Induced and Genetic Models of NAFLD.

por Park, Se-Hyung, Helsley, Robert N., Fadhul, Taghreed, Willoughby, Jennifer L.S., Noetzli, Leila, Tu, Ho-Chou, Solheim, Marie H., Fujisaka, Shiho, Pan, Hui, Dreyfuss, Jonathan M., Bons, Joanna, Rose, Jacob, King, Christina D., Schilling, Birgit, Lusis, Aldons J., Pan, Calvin, Gupta, Manoj, Kulkarni, Rohit N., Fitzgerald, Kevin, Kern, Philip A., Divanovic, Senad, Kahn, C. Ronald, Softic, Samir
Publicado 2023

Obesity-linked suppression of membrane-bound O-acyltransferase 7 (MBOAT7) drives non-alcoholic fatty liver disease

por Helsley, Robert N, Varadharajan, Venkateshwari, Brown, Amanda L, Gromovsky, Anthony D, Schugar, Rebecca C, Ramachandiran, Iyappan, Fung, Kevin, Kabbany, Mohammad Nasser, Banerjee, Rakhee, Neumann, Chase K, Finney, Chelsea, Pathak, Preeti, Orabi, Danny, Osborn, Lucas J, Massey, William, Zhang, Renliang, Kadam, Anagha, Sansbury, Brian E, Pan, Calvin, Sacks, Jessica, Lee, Richard G, Crooke, Rosanne M, Graham, Mark J, Lemieux, Madeleine E, Gogonea, Valentin, Kirwan, John P, Allende, Daniela S, Civelek, Mete, Fox, Paul L, Rudel, Lawrence L, Lusis, Aldons J, Spite, Matthew, Brown, J Mark
Publicado 2019

Gut microbe-targeted choline trimethylamine lyase inhibition improves obesity via rewiring of host circadian rhythms

por Schugar, Rebecca C, Gliniak, Christy M, Osborn, Lucas J, Massey, William, Sangwan, Naseer, Horak, Anthony, Banerjee, Rakhee, Orabi, Danny, Helsley, Robert N, Brown, Amanda L, Burrows, Amy, Finney, Chelsea, Fung, Kevin K, Allen, Frederick M, Ferguson, Daniel, Gromovsky, Anthony D, Neumann, Chase, Cook, Kendall, McMillan, Amy, Buffa, Jennifer A, Anderson, James T, Mehrabian, Margarete, Goudarzi, Maryam, Willard, Belinda, Mak, Tytus D, Armstrong, Andrew R, Swanson, Garth, Keshavarzian, Ali, Garcia-Garcia, Jose Carlos, Wang, Zeneng, Lusis, Aldons J, Hazen, Stanley L, Brown, Jonathan Mark
Publicado 2022

Gut microbial trimethylamine is elevated in alcohol-associated hepatitis and contributes to ethanol-induced liver injury in mice

por Helsley, Robert N, Miyata, Tatsunori, Kadam, Anagha, Varadharajan, Venkateshwari, Sangwan, Naseer, Huang, Emily C, Banerjee, Rakhee, Brown, Amanda L, Fung, Kevin K, Massey, William J, Neumann, Chase, Orabi, Danny, Osborn, Lucas J, Schugar, Rebecca C, McMullen, Megan R, Bellar, Annette, Poulsen, Kyle L, Kim, Adam, Pathak, Vai, Mrdjen, Marko, Anderson, James T, Willard, Belinda, McClain, Craig J, Mitchell, Mack, McCullough, Arthur J, Radaeva, Svetlana, Barton, Bruce, Szabo, Gyongyi, Dasarathy, Srinivasan, Garcia-Garcia, Jose Carlos, Rotroff, Daniel M, Allende, Daniela S, Wang, Zeneng, Hazen, Stanley L, Nagy, Laura E, Brown, Jonathan Mark
Publicado 2022