Loss of PKBβ/Akt2 predisposes mice to ovarian cyst formation and increases the severity of polycystic ovary formation in vivo

por Restuccia, David F., Hynx, Debby, Hemmings, Brian A.
Publicado 2012

PromoterPlot: a graphical display of promoter similarities by pattern recognition

por Di Cara, Alessandro, Schmidt, Karsten, Hemmings, Brian A., Oakeley, Edward J.
Publicado 2005

Deletion of PKBα/Akt1 Affects Thymic Development

por Fayard, Elisabeth, Gill, Jason, Paolino, Magdalena, Hynx, Debby, Holländer, Georg A., Hemmings, Brian A.
Publicado 2007

Deltex-1 Activates Mitotic Signaling and Proliferation and Increases the Clonogenic and Invasive Potential of U373 and LN18 Glioblastoma Cells and Correlates with Patient Survival

por Huber, Roland M., Rajski, Michal, Sivasankaran, Balasubramanian, Moncayo, Gerald, Hemmings, Brian A., Merlo, Adrian
Publicado 2013

The Akt1 isoform is an essential mediator of ischaemic preconditioning

por Kunuthur, Suma P, Mocanu, Mihaela M, Hemmings, Brian A, Hausenloy, Derek J, Yellon, Derek M
Publicado 2012

AKT-ions with a TWIST between EMT and MET

por Tang, Huifang, Massi, Daniela, Hemmings, Brian A., Mandalà, Mario, Hu, Zhengqiang, Wicki, Andreas, Xue, Gongda
Publicado 2016

Multimodal imaging reveals a role for Akt1 in fetal cardiac development

por Vandoorne, Katrien, Vandsburger, Moriel H, Weisinger, Karen, Brumfeld, Vlad, Hemmings, Brian A, Harmelin, Alon, Neeman, Michal
Publicado 2013

The endogenous inhibitor of Akt, CTMP, is critical to ischemia-induced neuronal death

por Miyawaki, Takahiro, Ofengeim, Dimitry, Noh, Kyung-Min, Latuszek-Barrantes, Adrianna, Hemmings, Brian A., Follenzi, Antonia, Zukin, R. Suzanne
Publicado 2009

The Hemodynamic Basis for Positional- and Inter-Fetal Dependent Effects in Dual Arterial Supply of Mouse Pregnancies

por Raz, Tal, Avni, Reut, Addadi, Yoseph, Cohen, Yoni, Jaffa, Ariel J., Hemmings, Brian, Garbow, Joel R., Neeman, Michal
Publicado 2012

GSK3β Regulates Differentiation and Growth Arrest in Glioblastoma

por Korur, Serdar, Huber, Roland M., Sivasankaran, Balasubramanian, Petrich, Michael, Morin, Pier, Hemmings, Brian A., Merlo, Adrian, Lino, Maria Maddalena
Publicado 2009

Intramolecular and Intermolecular Interactions of Protein Kinase B Define Its Activation In Vivo

por Calleja, Véronique, Alcor, Damien, Laguerre, Michel, Park, Jongsun, Vojnovic, Borivoj, Hemmings, Brian A, Downward, Julian, Parker, Peter J, Larijani, Banafshé
Publicado 2007

Phosphorylation of the Twist1-Family Basic Helix-Loop-Helix Transcription Factors Is Involved in Pathological Cardiac Remodeling

por Lu, Shuangshuang, Nie, Junwei, Luan, Qing, Feng, Qiuting, Xiao, Qi, Chang, Zai, Shan, Congjia, Hess, Daniel, Hemmings, Brian A., Yang, Zhongzhou
Publicado 2011

All Akt Isoforms (Akt1, Akt2, Akt3) Are Involved in Normal Hearing, but Only Akt2 and Akt3 Are Involved in Auditory Hair Cell Survival in the Mammalian Inner Ear

por Brand, Yves, Levano, Soledad, Radojevic, Vesna, Naldi, Arianne Monge, Setz, Cristian, Ryan, Allen F., Pak, Kwang, Hemmings, Brian A., Bodmer, Daniel
Publicado 2015

The Carboxy-Terminal Modulator Protein (CTMP) Regulates Mitochondrial Dynamics

por Parcellier, Arnaud, Tintignac, Lionel A., Zhuravleva, Elena, Dummler, Bettina, Brazil, Derek P., Hynx, Debby, Cron, Peter, Schenk, Susanne, Olivieri, Vesna, Hemmings, Brian A.
Publicado 2009

NDR Functions as a Physiological YAP1 Kinase in the Intestinal Epithelium

por Zhang, Lei, Tang, Fengyuan, Terracciano, Luigi, Hynx, Debby, Kohler, Reto, Bichet, Sandrine, Hess, Daniel, Cron, Peter, Hemmings, Brian A., Hergovich, Alexander, Schmitz-Rohmer, Debora
Publicado 2015

NDR Kinases Are Essential for Somitogenesis and Cardiac Looping during Mouse Embryonic Development

por Schmitz-Rohmer, Debora, Probst, Simone, Yang, Zhong-Zhou, Laurent, Frédéric, Stadler, Michael B., Zuniga, Aimée, Zeller, Rolf, Hynx, Debby, Hemmings, Brian A., Hergovich, Alexander
Publicado 2015

Heat shock protein 70-mediated sensitization of cells to apoptosis by Carboxyl-Terminal Modulator Protein

por Piao, Longzhen, Li, Yuwen, Yang, Keum-Jin, Park, Kyeong Ah, Byun, Hee Sun, Won, Minho, Hong, Janghee, Kim, Jeong-Lan, Kweon, Gi Ryang, Hur, Gang Min, Seok, Jeong Ho, Cho, Jae Youl, Chun, Taehoon, Hess, Daniel, Sack, Ragna, Maira, Sauveur-Michel, Brazil, Derek P, Hemmings, Brian A, Park, Jongsun
Publicado 2009

mTORC1/autophagy-regulated MerTK in mutant BRAFV600 melanoma with acquired resistance to BRAF inhibition

por Xue, Gongda, Kohler, Reto, Tang, Fengyuan, Hynx, Debby, Wang, Yuhua, Orso, Francesca, Prêtre, Vincent, Ritschard, Reto, Hirschmann, Petra, Cron, Peter, Roloff, Tim, Dummer, Reinhard, Mandalà, Mario, Bichet, Sandrine, Genoud, Christel, Meyer, Alexandra G., Muraro, Manuele G., Spagnoli, Giulio C., Taverna, Daniela, Rüegg, Curzio, Merghoub, Taha, Massi, Daniela, Tang, Huifang, Levesque, Mitchell P., Dirnhofer, Stephan, Zippelius, Alfred, Hemmings, Brian A., Wicki, Andreas
Publicado 2017