Structure-Guided Design and In-Cell Target Profiling of a Cell-Active Target Engagement Probe for PARP Inhibitors

por Howard, Ryan T., Hemsley, Paul, Petteruti, Philip, Saunders, Charlie N., Molina Bermejo, Javier A., Scott, James S., Johannes, Jeffrey W., Tate, Edward W.
Publicado 2020

Positioning High-Throughput CETSA in Early Drug Discovery through Screening against B-Raf and PARP1

por Shaw, Joseph, Dale, Ian, Hemsley, Paul, Leach, Lindsey, Dekki, Nancy, Orme, Jonathan P., Talbot, Verity, Narvaez, Ana J., Bista, Michal, Martinez Molina, Daniel, Dabrowski, Michael, Main, Martin J., Gianni, Davide
Publicado 2018