The function of chromatin modifiers in lineage commitment and cell fate specification

por Signolet, Jason, Hendrich, Brian
Publicado 2015

CHD4 in the DNA-damage response and cell cycle progression: not so NuRDy now

por O’Shaughnessy, Aoife, Hendrich, Brian
Publicado 2013

The Methyl-CpG Binding Proteins Mecp2, Mbd2 and Kaiso Are Dispensable for Mouse Embryogenesis, but Play a Redundant Function in Neural Differentiation

por Martín Caballero, Isabel, Hansen, Janne, Leaford, Donna, Pollard, Steven, Hendrich, Brian D.
Publicado 2009

Constraint of gene expression by the chromatin remodelling protein CHD4 facilitates lineage specification

por O'Shaughnessy-Kirwan, Aoife, Signolet, Jason, Costello, Ita, Gharbi, Sarah, Hendrich, Brian
Publicado 2015

Sin3a is essential for the genome integrity and viability of pluripotent cells

por McDonel, Patrick, Demmers, Jeroen, Tan, David W.M., Watt, Fiona, Hendrich, Brian D.
Publicado 2012

The methyl binding domain 3/nucleosome remodelling and deacetylase complex regulates neural cell fate determination and terminal differentiation in the cerebral cortex

por Knock, Erin, Pereira, João, Lombard, Patrick D, Dimond, Andrew, Leaford, Donna, Livesey, Frederick J, Hendrich, Brian
Publicado 2015

Sall4 controls differentiation of pluripotent cells independently of the Nucleosome Remodelling and Deacetylation (NuRD) complex

por Miller, Anzy, Ralser, Meryem, Kloet, Susan L., Loos, Remco, Nishinakamura, Ryuichi, Bertone, Paul, Vermeulen, Michiel, Hendrich, Brian
Publicado 2016

NuRD-dependent DNA methylation prevents ES cells from accessing a trophectoderm fate

por Latos, Paulina A., Helliwell, Christine, Mosaku, Olukunbi, Dudzinska, Dominika A., Stubbs, Bryony, Berdasco, Maria, Esteller, Manel, Hendrich, Brian
Publicado 2012

MBD3/NuRD Facilitates Induction of Pluripotency in a Context-Dependent Manner

por dos Santos, Rodrigo L., Tosti, Luca, Radzisheuskaya, Aliaksandra, Caballero, Isabel M., Kaji, Keisuke, Hendrich, Brian, Silva, José C.R.
Publicado 2014

MBD3/NuRD Facilitates Induction of Pluripotency in a Context-Dependent Manner

por dos Santos, Rodrigo L., Tosti, Luca, Radzisheuskaya, Aliaksandra, Caballero, Isabel M., Kaji, Keisuke, Hendrich, Brian, Silva, José C.R.
Publicado 2014

Differential regulation of lineage commitment in human and mouse primed pluripotent stem cells by the nucleosome remodelling and deacetylation complex

por Ragheb, Ramy, Gharbi, Sarah, Cramard, Julie, Ogundele, Oluwaseun, Kloet, Susan L., Burgold, Thomas, Vermeulen, Michiel, Reynolds, Nicola, Hendrich, Brian
Publicado 2020

NuRD-mediated deacetylation of H3K27 facilitates recruitment of Polycomb Repressive Complex 2 to direct gene repression

por Reynolds, Nicola, Salmon-Divon, Mali, Dvinge, Heidi, Hynes-Allen, Antony, Balasooriya, Gayan, Leaford, Donna, Behrens, Axel, Bertone, Paul, Hendrich, Brian
Publicado 2012

A high-resolution map of transcriptional repression

por Liang, Ziwei, Brown, Karen E, Carroll, Thomas, Taylor, Benjamin, Vidal, Isabel Ferreirós, Hendrich, Brian, Rueda, David, Fisher, Amanda G, Merkenschlager, Matthias
Publicado 2017

The Nucleosome Remodeling and Deacetylation Complex Modulates Chromatin Structure at Sites of Active Transcription to Fine-Tune Gene Expression

por Bornelöv, Susanne, Reynolds, Nicola, Xenophontos, Maria, Gharbi, Sarah, Johnstone, Ewan, Floyd, Robin, Ralser, Meryem, Signolet, Jason, Loos, Remco, Dietmann, Sabine, Bertone, Paul, Hendrich, Brian
Publicado 2018

The Nucleosome Remodelling and Deacetylation complex suppresses transcriptional noise during lineage commitment

por Burgold, Thomas, Barber, Michael, Kloet, Susan, Cramard, Julie, Gharbi, Sarah, Floyd, Robin, Kinoshita, Masaki, Ralser, Meryem, Vermeulen, Michiel, Reynolds, Nicola, Dietmann, Sabine, Hendrich, Brian
Publicado 2019

MeCP2 Dependent Heterochromatin Reorganization during Neural Differentiation of a Novel Mecp2-Deficient Embryonic Stem Cell Reporter Line

por Bertulat, Bianca, De Bonis, Maria Luigia, Della Ragione, Floriana, Lehmkuhl, Anne, Milden, Manuela, Storm, Christian, Jost, K. Laurence, Scala, Simona, Hendrich, Brian, D’Esposito, Maurizio, Cardoso, M. Cristina
Publicado 2012

Mbd3/NuRD controls lymphoid cell fate and inhibits tumorigenesis by repressing a B cell transcriptional program

por Loughran, Stephen J., Comoglio, Federico, Hamey, Fiona K., Giustacchini, Alice, Errami, Youssef, Earp, Eleanor, Göttgens, Berthold, Jacobsen, Sten Eirik W., Mead, Adam J., Hendrich, Brian, Green, Anthony R.
Publicado 2017

The opposing transcriptional functions of Sin3A and c-Myc are required to maintain tissue homeostasis

por Nascimento, Elisabete M., Cox, Claire L., MacArthur, Stewart, Hussain, Shobbir, Trotter, Matthew, Blanco, Sandra, Suraj, Menon, Nichols, Jennifer, Kübler, Bernd, Benitah, Salvador Aznar, Hendrich, Brian, Odom, Duncan T., Frye, Michaela
Publicado 2011

NuRD Suppresses Pluripotency Gene Expression to Promote Transcriptional Heterogeneity and Lineage Commitment

por Reynolds, Nicola, Latos, Paulina, Hynes-Allen, Antony, Loos, Remco, Leaford, Donna, O'Shaughnessy, Aoife, Mosaku, Olukunbi, Signolet, Jason, Brennecke, Philip, Kalkan, Tüzer, Costello, Ita, Humphreys, Peter, Mansfield, William, Nakagawa, Kentaro, Strouboulis, John, Behrens, Axel, Bertone, Paul, Hendrich, Brian
Publicado 2012

FRET-enhanced photostability allows improved single-molecule tracking of proteins and protein complexes in live mammalian cells

por Basu, Srinjan, Needham, Lisa-Maria, Lando, David, Taylor, Edward J. R., Wohlfahrt, Kai J., Shah, Devina, Boucher, Wayne, Tan, Yi Lei, Bates, Lawrence E., Tkachenko, Olga, Cramard, Julie, Lagerholm, B. Christoffer, Eggeling, Christian, Hendrich, Brian, Klenerman, Dave, Lee, Steven F., Laue, Ernest D.
Publicado 2018