Co-morbidity and systemic inflammation as drivers of cognitive decline: new experimental models adopting a broader paradigm in dementia research

por Cunningham, Colm, Hennessy, Edel
Publicado 2015

A Systematic Analysis of the Peripheral and CNS Effects of Systemic LPS, IL-1Β, TNF-α and IL-6 Challenges in C57BL/6 Mice

por Skelly, Donal T., Hennessy, Edel, Dansereau, Marc-Andre, Cunningham, Colm
Publicado 2013

Correction: A Systematic Analysis of the Peripheral and CNS Effects of Systemic LPS, IL-1β, TNF-α and IL-6 Challenges in C57BL/6 Mice

por Skelly, Donal T., Hennessy, Edel, Dansereau, Marc-Andre, Cunningham, Colm
Publicado 2013

At the centre of neuronal, synaptic and axonal pathology in murine prion disease: degeneration of neuroanatomically linked thalamic and brainstem nuclei

por Reis, Renata, Hennessy, Edel, Murray, Caoimhe, Griffin, Éadaoin W., Cunningham, Colm
Publicado 2015

Systemic TNF-α produces acute cognitive dysfunction and exaggerated sickness behavior when superimposed upon progressive neurodegeneration

por Hennessy, Edel, Gormley, Shane, Lopez-Rodriguez, Ana Belen, Murray, Caoimhe, Murray, Carol, Cunningham, Colm
Publicado 2017

OptiCogs: feasibility of a multicomponent intervention to rehabilitate people with cognitive impairment post-stroke

por O’ Donoghue, Mairéad, Boland, Pauline, Taylor, Sinead, Hennessy, Edel, Murphy, Eva, Leahy, Siobhan, McManus, John, Lisiecka, Dominika, Purtill, Helen, Galvin, Rose, Hayes, Sara
Publicado 2023

Acute transient cognitive dysfunction and acute brain injury induced by systemic inflammation occur by dissociable IL-1-dependent mechanisms

por Skelly, Donal T., Griffin, Éadaoin W., Murray, Carol L., Harney, Sarah, O’Boyle, Conor, Hennessy, Edel, Dansereau, Marc-Andre, Nazmi, Arshed, Tortorelli, Lucas, Rawlins, J. Nicholas, Bannerman, David M., Cunningham, Colm
Publicado 2018

Correction: Acute transient cognitive dysfunction and acute brain injury induced by systemic inflammation occur by dissociable IL-1-dependent mechanisms

por Skelly, Donal T., Griffin, Éadaoin W., Murray, Carol L., Harney, Sarah, O’Boyle, Conor, Hennessy, Edel, Dansereau, Marc-Andre, Nazmi, Arshed, Tortorelli, Lucas, Rawlins, J. Nicholas, Bannerman, David M., Cunningham, Colm
Publicado 2019

Double stranded RNA drives innate immune responses, sickness behavior and cognitive impairment dependent on dsRNA length, IFNAR1 expression and age.

por McGarry, Niamh, Murray, Carol L., Garvey, Sean, Wilkinson, Abigail, Tortorelli, Lucas, Ryan, Lucy, Hayden, Lorna, Healy, Daire, Griffin, Eadaoin. W., Hennessy, Edel, Arumugam, Malathy, Skelly, Donal T., Mitchell, Kevin J., Cunningham, Colm
Publicado 2021

Double stranded RNA drives anti-viral innate immune responses, sickness behavior and cognitive dysfunction dependent on dsRNA length, IFNAR1 expression and age

por McGarry, Niamh, Murray, Carol L., Garvey, Sean, Wilkinson, Abigail, Tortorelli, Lucas, Ryan, Lucy, Hayden, Lorna, Healy, Daire, Griffin, Eadaoin W., Hennessy, Edel, Arumugam, Malathy, Skelly, Donal T., Mitchell, Kevin J., Cunningham, Colm
Publicado 2021

Chronic neurodegeneration induces type I interferon synthesis via STING, shaping microglial phenotype and accelerating disease progression

por Nazmi, Arshed, Field, Robert H., Griffin, Eadaoin W., Haugh, Orla, Hennessy, Edel, Cox, Donal, Reis, Renata, Tortorelli, Lucas, Murray, Carol L., Lopez‐Rodriguez, Ana Belen, Jin, Lei, Lavelle, Ed C., Dunne, Aisling, Cunningham, Colm
Publicado 2019

Worsening Cognitive Impairment and Neurodegenerative Pathology Progressively Increase Risk for Delirium

por Davis, Daniel H.J., Skelly, Donal T., Murray, Carol, Hennessy, Edel, Bowen, Jordan, Norton, Samuel, Brayne, Carol, Rahkonen, Terhi, Sulkava, Raimo, Sanderson, David J., Rawlins, J. Nicholas, Bannerman, David M., MacLullich, Alasdair M.J., Cunningham, Colm
Publicado 2015