Individualized Dosing of Fluoropyrimidine‐Based Chemotherapy to Prevent Severe Fluoropyrimidine‐Related Toxicity: What Are the Options?

por Knikman, Jonathan E., Gelderblom, Hans, Beijnen, Jos H., Cats, Annemieke, Guchelaar, Henk‐Jan, Henricks, Linda M.
Publicado 2020

Diagnostic and Therapeutic Strategies for Fluoropyrimidine Treatment of Patients Carrying Multiple DPYD Variants

por Lunenburg, Carin A. T. C., Henricks, Linda M., van Kuilenburg, André B. P., Mathijssen, Ron H. J., Schellens, Jan H. M., Gelderblom, Hans, Guchelaar, Henk-Jan, Swen, Jesse J.
Publicado 2018

Food‐effect study on uracil and dihydrouracil plasma levels as marker for dihydropyrimidine dehydrogenase activity in human volunteers

por Henricks, Linda M., Jacobs, Bart A. W., Meulendijks, Didier, Pluim, Dick, van den Broek, Daan, de Vries, Niels, Rosing, Hilde, Beijnen, Jos H., Huitema, Alwin D. R., Guchelaar, Henk‐Jan, Cats, Annemieke, Schellens, Jan H. M.
Publicado 2018

Pretreatment serum uracil concentration as a predictor of severe and fatal fluoropyrimidine-associated toxicity

por Meulendijks, Didier, Henricks, Linda M, Jacobs, Bart A W, Aliev, Abidin, Deenen, Maarten J, de Vries, Niels, Rosing, Hilde, van Werkhoven, Erik, de Boer, Anthonius, Beijnen, Jos H, Mandigers, Caroline M P W, Soesan, Marcel, Cats, Annemieke, Schellens, Jan H M
Publicado 2017

Dihydropyrimidine Dehydrogenase Phenotyping Using Pretreatment Uracil: A Note of Caution Based on a Large Prospective Clinical Study

por de With, Mirjam, Knikman, Jonathan, de Man, Femke M., Lunenburg, Carin A. T. C., Henricks, Linda M., van Kuilenburg, André B. P., Maring, Jan G., van Staveren, Maurice C., de Vries, Niels, Rosing, Hilde, Beijnen, Jos H., Pluim, Dick, Modak, Anil, Imholz, Alex L. T., van Schaik, Ron H. N., Schellens, Jan H. M., Gelderblom, Hans, Cats, Annemieke, Guchelaar, Henk‐Jan, Mathijssen, Ron H. J., Swen, Jesse J., Meulendijks, Didier
Publicado 2022