Chaperoning to the metabolic party: The emerging therapeutic role of heat-shock proteins in obesity and type 2 diabetes

por Henstridge, Darren C., Whitham, Martin, Febbraio, Mark A.
Publicado 2014

Muscle-specific overexpression of AdipoR1 or AdipoR2 gives rise to common and discrete local effects whilst AdipoR2 promotes additional systemic effects

por Keshvari, Sahar, Henstridge, Darren C., Ng, Choaping, Febbraio, Mark A., Whitehead, Jonathan P.
Publicado 2017

The Zinc Transporter Zip7 Is Downregulated in Skeletal Muscle of Insulin-Resistant Cells and in Mice Fed a High-Fat Diet

por Norouzi, Shaghayegh, Adulcikas, John, Henstridge, Darren C, Sonda, Sabrina, Sohal, Sukhwinder Singh, Myers, Stephen
Publicado 2019

Single or combined ablation of peripheral serotonin and p21 limit adipose tissue expansion and metabolic alterations in early adulthood in mice fed a normocaloric diet

por Saponara, Enrica, Chen, Rong, Reding, Theresia, Zuellig, Richard, Henstridge, Darren C., Graf, Rolf, Sonda, Sabrina
Publicado 2021

1-Deoxysphingolipids, Early Predictors of Type 2 Diabetes, Compromise the Functionality of Skeletal Myoblasts

por Tran, Duyen, Myers, Stephen, McGowan, Courtney, Henstridge, Darren, Eri, Rajaraman, Sonda, Sabrina, Caruso, Vanni
Publicado 2021

In Vitro Palmitate Treatment of Myotubes from Postmenopausal Women Leads to Ceramide Accumulation, Inflammation and Affected Insulin Signaling

por Abildgaard, Julie, Henstridge, Darren C., Pedersen, Anette T., Langley, Katherine G., Scheele, Camilla, Pedersen, Bente Klarlund, Lindegaard, Birgitte
Publicado 2014

Over-expressing the soluble gp130-Fc does not ameliorate methionine and choline deficient diet-induced non alcoholic steatohepatitis in mice

por Kammoun, Helene L., Allen, Tamara Louise, Henstridge, Darren Colin, Kraakman, Michael James, Peijs, Lone, Rose-John, Stefan, Febbraio, Mark Anthony
Publicado 2017

High Fat Diet Inhibits Dendritic Cell and T Cell Response to Allergens but Does Not Impair Inhalational Respiratory Tolerance

por Pizzolla, Angela, Oh, Ding Yuan, Luong, Suzanne, Prickett, Sara R., Henstridge, Darren C., Febbraio, Mark A., O’Hehir, Robyn E., Rolland, Jennifer M., Hardy, Charles L.
Publicado 2016

p32 protein levels are integral to mitochondrial and endoplasmic reticulum morphology, cell metabolism and survival

por Hu, MengJie, Crawford, Simon A., Henstridge, Darren C., Ng, Ivan H. W., Boey, Esther J. H., Xu, Yuekang, Febbraio, Mark A., Jans, David A., Bogoyevitch, Marie A.
Publicado 2013

Metabolically active CD4+ T cells expressing Glut1 and OX40 preferentially harbor HIV during in vitro infection

por Palmer, Clovis S., Duette, Gabriel A., Wagner, Marc C. E., Henstridge, Darren C., Saleh, Suah, Pereira, Candida, Zhou, Jingling, Simar, David, Lewin, Sharon R., Ostrowski, Matias, McCune, Joseph M., Crowe, Suzanne M.
Publicado 2017

c-Jun NH(2)-Terminal Kinase Activity in Subcutaneous Adipose Tissue but Not Nuclear Factor-κB Activity in Peripheral Blood Mononuclear Cells Is an Independent Determinant of Insuli...

por Sourris, Karly C., Lyons, Jasmine G., de Courten, Maximilian P.J., Dougherty, Sonia L., Henstridge, Darren C., Cooper, Mark E., Hage, Michelle, Dart, Anthony, Kingwell, Bronwyn A., Forbes, Josephine M., de Courten, Barbora
Publicado 2009

Ceramides Contained in LDL Are Elevated in Type 2 Diabetes and Promote Inflammation and Skeletal Muscle Insulin Resistance

por Boon, James, Hoy, Andrew J., Stark, Romana, Brown, Russell D., Meex, Ruth C., Henstridge, Darren C., Schenk, Simon, Meikle, Peter J., Horowitz, Jeffrey F., Kingwell, Bronwyn A., Bruce, Clinton R., Watt, Matthew J.
Publicado 2013

HSP72 Is a Mitochondrial Stress Sensor Critical for Parkin Action, Oxidative Metabolism, and Insulin Sensitivity in Skeletal Muscle

por Drew, Brian G., Ribas, Vicente, Le, Jamie A., Henstridge, Darren C., Phun, Jennifer, Zhou, Zhenqi, Soleymani, Teo, Daraei, Pedram, Sitz, Daniel, Vergnes, Laurent, Wanagat, Jonathan, Reue, Karen, Febbraio, Mark A., Hevener, Andrea L.
Publicado 2014

Respiratory syncytial virus co-opts host mitochondrial function to favour infectious virus production

por Hu, MengJie, Schulze, Keith E, Ghildyal, Reena, Henstridge, Darren C, Kolanowski, Jacek L, New, Elizabeth J, Hong, Yuning, Hsu, Alan C, Hansbro, Philip M, Wark, Peter AB, Bogoyevitch, Marie A, Jans, David A
Publicado 2019

Effects of water stably-enriched with oxygen as a novel method of tissue oxygenation on mitochondrial function, and as adjuvant therapy for type 2 diabetes in a randomized placebo-...

por Khoo, Joan, Hagemeyer, Christoph E., Henstridge, Darren C., Kumble, Sumukh, Wang, Ting-Yi, Xu, Rong, Gani, Linsey, King, Thomas, Soh, Shui-Boon, Puar, Troy, Au, Vanessa, Tan, Eberta, Tay, Tunn-Lin, Kam, Carmen, Teo, Eng-Kiong
Publicado 2021

Glycolysis Is Required for LPS-Induced Activation and Adhesion of Human CD14(+)CD16(−) Monocytes

por Lee, Man K. S., Al-Sharea, Annas, Shihata, Waled A., Bertuzzo Veiga, Camilla, Cooney, Olivia D., Fleetwood, Andrew J., Flynn, Michelle C., Claeson, Ellen, Palmer, Clovis S., Lancaster, Graeme I., Henstridge, Darren C., Hamilton, John A., Murphy, Andrew J.
Publicado 2019

Maternal obesity and diabetes induces latent metabolic defects and widespread epigenetic changes in isogenic mice

por Li, Cheryl C.Y., Young, Paul E., Maloney, Christopher A., Eaton, Sally A., Cowley, Mark J., Buckland, Michael E, Preiss, Thomas, Henstridge, Darren C., Cooney, Gregory J., Febbraio, Mark A., Martin, David I.K., Cropley, Jennifer E., Suter, Catherine M.
Publicado 2013

Activating HSP72 in Rodent Skeletal Muscle Increases Mitochondrial Number and Oxidative Capacity and Decreases Insulin Resistance

por Henstridge, Darren C., Bruce, Clinton R., Drew, Brian G., Tory, Kálmán, Kolonics, Attila, Estevez, Emma, Chung, Jason, Watson, Nadine, Gardner, Timothy, Lee-Young, Robert S., Connor, Timothy, Watt, Matthew J., Carpenter, Kevin, Hargreaves, Mark, McGee, Sean L., Hevener, Andrea L., Febbraio, Mark A.
Publicado 2014

Male-lineage transmission of an acquired metabolic phenotype induced by grand-paternal obesity

por Cropley, Jennifer E., Eaton, Sally A., Aiken, Alastair, Young, Paul E., Giannoulatou, Eleni, Ho, Joshua W.K., Buckland, Michael E., Keam, Simon P., Hutvagner, Gyorgy, Humphreys, David T., Langley, Katherine G., Henstridge, Darren C., Martin, David I.K., Febbraio, Mark A., Suter, Catherine M.
Publicado 2016

Deletion of Trim28 in committed adipocytes promotes obesity but preserves glucose tolerance

por Bond, Simon T., King, Emily J., Henstridge, Darren C., Tran, Adrian, Moody, Sarah C., Yang, Christine, Liu, Yingying, Mellett, Natalie A., Nath, Artika P., Inouye, Michael, Tarling, Elizabeth J., de Aguiar Vallim, Thomas Q., Meikle, Peter J., Calkin, Anna C., Drew, Brian G.
Publicado 2021