In Silico Non-Homologous End Joining Following Ion Induced DNA Double Strand Breaks Predicts That Repair Fidelity Depends on Break Density

por Henthorn, N. T., Warmenhoven, J. W., Sotiropoulos, M., Mackay, R. I., Kirkby, N. F., Kirkby, K. J., Merchant, M. J.
Publicado 2018

Mechanistic modelling supports entwined rather than exclusively competitive DNA double-strand break repair pathway

por Ingram, S. P., Warmenhoven, J. W., Henthorn, N. T., Smith, E. A. K., Chadwick, A. L., Burnet, N. G., Mackay, R. I., Kirkby, N. F., Kirkby, K. J., Merchant, M. J.
Publicado 2019

Clinically relevant nanodosimetric simulation of DNA damage complexity from photons and protons

por Henthorn, N. T., Warmenhoven, J. W., Sotiropoulos, M., Aitkenhead, A. H., Smith, E. A. K., Ingram, S. P., Kirkby, N. F., Chadwick, A. L., Burnet, N. G., Mackay, R. I., Kirkby, K. J., Merchant, M. J.
Publicado 2019

Evaluating very high energy electron RBE from nanodosimetric pBR322 plasmid DNA damage

por Small, K L, Henthorn, N T, Angal-Kalinin, D, Chadwick, A L, Santina, E, Aitkenhead, A, Kirkby, K J, Smith, R J, Surman, M, Jones, J, Farabolini, W, Corsini, R, Gamba, D, Gilardi, A, Merchant, M J, Jones, R M
Publicado 2021

In Silico Models of DNA Damage and Repair in Proton Treatment Planning: A Proof of Concept

por Smith, Edward A. K., Henthorn, N. T., Warmenhoven, J. W., Ingram, S. P., Aitkenhead, A. H., Richardson, J. C., Sitch, P., Chadwick, A. L., Underwood, T. S. A., Merchant, M. J., Burnet, N. G., Kirkby, N. F., Kirkby, K. J., Mackay, R. I.
Publicado 2019

Evaluating very high energy electron RBE from nanodosimetric pBR322 plasmid DNA damage

por Small, K. L., Henthorn, N. T., Angal-Kalinin, D., Chadwick, A. L., Santina, E., Aitkenhead, A., Kirkby, K. J., Smith, R. J., Surman, M., Jones, J., Farabolini, W., Corsini, R., Gamba, D., Gilardi, A., Merchant, M. J., Jones, R. M.
Publicado 2021