Pharmacological validation of a novel nonhuman primate measure of thermal responsivity with utility for predicting analgesic effects

por Vardigan, Joshua D, Houghton, Andrea K, Lange, Henry S, Adarayan, Emily D, Pall, Parul S, Ballard, Jeanine E, Henze, Darrell A, Uslaner, Jason M
Publicado 2018

HC-030031, a TRPA1 selective antagonist, attenuates inflammatory- and neuropathy-induced mechanical hypersensitivity

por Eid, Samer R, Crown, Eric D, Moore, Eric L, Liang, Hongyu A, Choong, Kar-Chan, Dima, Shelley, Henze, Darrell A, Kane, Stefanie A, Urban, Mark O
Publicado 2008

Translational Pharmacokinetic–Pharmacodynamic Modeling of NaV1.7 Inhibitor MK-2075 to Inform Human Efficacious Dose

por Ballard, Jeanine E., Pall, Parul S., Vardigan, Joshua, Zhao, Fuqiang, Holahan, Marie A., Zhou, Xiaoping, Jochnowitz, Nina, Kraus, Richard L., Klein, Rebecca M., Henze, Darrell A., Houghton, Andrea K., Burgey, Christopher S., Gibson, Christopher, Struyk, Arie
Publicado 2021

Association of respiratory failure with inhibition of NaV1.6 in the phrenic nerve

por Klein, Rebecca M., Layton, Mark E., Regan, Hillary, Regan, Christopher P., Li, Yuxing, Filzen, Tracey, Cato, Matt, Clements, Michelle K., Wang, Jixin, Sanoja, Raul, Greshock, Thomas J., Roecker, Anthony J., Pero, Joseph E., Kim, Ron, Burgey, Christopher, John, Christopher T., Wang, Ying-Hong, Bhandari, Neetesh, Struyk, Arie, Kraus, Richard L., Henze, Darrell A., Houghton, Andrea K.
Publicado 2022