G protein coupled receptor signaling complexes in live cells

por Hepler, John R
Publicado 2014

Endogenous RGS14 is a cytoplasmic-nuclear shuttling protein that localizes to juxtanuclear membranes and chromatin-rich regions of the nucleus

por Branch, Mary Rose, Hepler, John R.
Publicado 2017

Regulator of G Protein Signaling 2 (RGS2) and RGS4 Form Distinct G Protein-Dependent Complexes with Protease Activated-Receptor 1 (PAR1) in Live Cells

por Ghil, Sungho, McCoy, Kelly L., Hepler, John R.
Publicado 2014

RGS14 regulates the lifetime of Gα‐GTP signaling but does not prolong Gβγ signaling following receptor activation in live cells

por Brown, Nicole E., Lambert, Nevin A., Hepler, John R.
Publicado 2016

RGS14 Regulation of Post-Synaptic Signaling and Spine Plasticity in Brain

por Harbin, Nicholas H., Bramlett, Sara N., Montanez-Miranda, Carolina, Terzioglu, Gizem, Hepler, John R.
Publicado 2021

RGS14 Restricts Plasticity in Hippocampal CA2 by Limiting Postsynaptic Calcium Signaling

por Evans, Paul R., Parra-Bueno, Paula, Smirnov, Michael S., Lustberg, Daniel J., Dudek, Serena M., Hepler, John R., Yasuda, Ryohei
Publicado 2018

RGS14 is neuroprotective against seizure-induced mitochondrial oxidative stress and pathology in hippocampus

por Harbin, Nicholas H, Lustberg, Daniel J, Hurst, Cheyenne, Pare, Jean-Francois, Crotty, Kathryn M, Waters, Alaina L, Yeligar, Samantha M, Smith, Yoland, Seyfried, Nicholas T, Weinshenker, David, Hepler, John R
Publicado 2023

RGS14 regulates PTH- and FGF23-sensitive NPT2A-mediated renal phosphate uptake via binding to the NHERF1 scaffolding protein

por Friedman, Peter A., Sneddon, W. Bruce, Mamonova, Tatyana, Montanez-Miranda, Carolina, Ramineni, Suneela, Harbin, Nicholas H., Squires, Katherine E., Gefter, Julia V., Magyar, Clara E., Emlet, David R., Hepler, John R.
Publicado 2022

Human genetic variants disrupt RGS14 nuclear shuttling and regulation of LTP in hippocampal neurons

por Squires, Katherine E., Gerber, Kyle J., Tillman, Matthew C., Lustberg, Daniel J., Montañez-Miranda, Carolina, Zhao, Meilan, Ramineni, Suneela, Scharer, Christopher D., Saha, Ramendra N., Shu, Feng-Jue, Schroeder, Jason P., Ortlund, Eric A., Weinshenker, David, Dudek, Serena M., Hepler, John R.
Publicado 2020

THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Introduction and Other Protein Targets

por Alexander, Stephen P H, Kelly, Eamonn, Mathie, Alistair, Peters, John A, Veale, Emma L, Armstrong, Jane F, Faccenda, Elena, Harding, Simon D, Pawson, Adam J, Southan, Christopher, Buneman, O Peter, Cidlowski, John A, Christopoulos, Arthur, Davenport, Anthony P, Fabbro, Doriano, Spedding, Michael, Striessnig, Jörg, Davies, Jamie A, Ahlers‐Dannen, Katelin E., Alqinyah, Mohammed, Arumugam, Thiruma V., Bodle, Christopher, Dagner, Josephine Buo, Chakravarti, Bandana, Choudhuri, Shreoshi P., Druey, Kirk M., Fisher, Rory A., Gerber, Kyle J., Hepler, John R., Hooks, Shelley B., Kantheti, Havish S., Karaj, Behirda, Layeghi‐Ghalehsoukhteh, Somayeh, Lee, Jae‐Kyung, Luo, Zili, Martemyanov, Kirill, Mascarenhas, Luke D., McNabb, Harrison, Montañez‐Miranda, Carolina, Ogujiofor, Osita, Phan, Hoa, Roman, David L., Shaw, Vincent, Sjogren, Benita, Sobey, Christopher, Spicer, Mackenzie M., Squires, Katherine E., Sutton, Laurie, Wendimu, Menbere, Wilkie, Thomas, Xie, Keqiang, Zhang, Qian, Zolghadri, Yalda
Publicado 2021