GLP-1 based therapeutics: simultaneously combating T2DM and obesity

por Heppner, Kristy M., Perez-Tilve, Diego
Publicado 2015

Targeting FXR and FGF19 to Treat Metabolic Diseases—Lessons Learned From Bariatric Surgery

por Bozadjieva, Nadejda, Heppner, Kristy M., Seeley, Randy J.
Publicado 2018

Ablation of Ghrelin O-Acyltransferase Does Not Improve Glucose Intolerance or Body Adiposity in Mice on a Leptin-Deficient ob/ob Background

por Kirchner, Henriette, Heppner, Kristy M., Holland, Jenna, Kabra, Dhiraj, Tschöp, Matthias H., Pfluger, Paul T.
Publicado 2013

Intestinal-derived FGF15 protects against deleterious effects of vertical sleeve gastrectomy in mice

por Bozadjieva-Kramer, Nadejda, Shin, Jae Hoon, Shao, Yikai, Gutierrez-Aguilar, Ruth, Li, Ziru, Heppner, Kristy M., Chiang, Samuel, Vargo, Sara G., Granger, Katrina, Sandoval, Darleen A., MacDougald, Ormond A., Seeley, Randy J.
Publicado 2021

Both Acyl and Des-Acyl Ghrelin Regulate Adiposity and Glucose Metabolism via Central Nervous System Ghrelin Receptors

por Heppner, Kristy M., Piechowski, Carolin L., Müller, Anne, Ottaway, Nickki, Sisley, Stephanie, Smiley, David L., Habegger, Kirk M., Pfluger, Paul T., DiMarchi, Richard, Biebermann, Heike, Tschöp, Matthias H., Sandoval, Darleen A., Perez-Tilve, Diego
Publicado 2014

GLP-1R Signaling Directly Activates Arcuate Nucleus Kisspeptin Action in Brain Slices but Does not Rescue Luteinizing Hormone Inhibition in Ovariectomized Mice During Negative Ener...

por Heppner, Kristy M., Baquero, Arian F., Bennett, Camdin M., Lindsley, Sarah R., Kirigiti, Melissa A., Bennett, Baylin, Bosch, Martha A., Mercer, Aaron J., Rønnekleiv, Oline K., True, Cadence, Grove, Kevin L., Smith, M. Susan
Publicado 2017

Direct Control of Brown Adipose Tissue Thermogenesis by Central Nervous System Glucagon-Like Peptide-1 Receptor Signaling

por Lockie, Sarah H., Heppner, Kristy M., Chaudhary, Nilika, Chabenne, Joseph R., Morgan, Donald A., Veyrat-Durebex, Christelle, Ananthakrishnan, Gayathri, Rohner-Jeanrenaud, Françoise, Drucker, Daniel J., DiMarchi, Richard, Rahmouni, Kamal, Oldfield, Brian J., Tschöp, Matthias H., Perez-Tilve, Diego
Publicado 2012

GLP-1R Agonism Enhances Adjustable Gastric Banding in Diet-Induced Obese Rats

por Habegger, Kirk M., Kirchner, Henriette, Yi, Chun-Xia, Heppner, Kristy M., Sweeney, Dan, Ottaway, Nickki, Holland, Jenna, Amburgy, Sarah, Raver, Christine, Krishna, Radhakrishna, Müller, Timo D., Perez-Tilve, Diego, Pfluger, Paul T., Obici, Silvana, DiMarchi, Richard D., D’Alessio, David A., Seeley, Randy J., Tschöp, Matthias H.
Publicado 2013

GLP-1R Responsiveness Predicts Individual Gastric Bypass Efficacy on Glucose Tolerance in Rats

por Habegger, Kirk M., Heppner, Kristy M., Amburgy, Sarah E., Ottaway, Nickki, Holland, Jenna, Raver, Christine, Bartley, Erin, Müller, Timo D., Pfluger, Paul T., Berger, Jose, Toure, Mouhamadoul, Benoit, Stephen C., DiMarchi, Richard D., Perez-Tilve, Diego, D’Alessio, David A., Seeley, Randy J., Tschöp, Matthias H.
Publicado 2014

The GOAT-Ghrelin System Is Not Essential for Hypoglycemia Prevention during Prolonged Calorie Restriction

por Yi, Chun-Xia, Heppner, Kristy M., Kirchner, Henriette, Tong, Jenny, Bielohuby, Maximillian, Gaylinn, Bruce D., Müller, Timo D., Bartley, Erin, Davis, Harold W., Zhao, Yongmei, Joseph, Anupama, Kruthaupt, Traci, Ottaway, Nickki, Kabra, Dhiraj, Habegger, Kirk M., Benoit, Stephen C., Bidlingmaier, Martin, Thorner, Michael O., Perez-Tilve, Diego, Tschöp, Matthias H., Pfluger, Paul T.
Publicado 2012

Reelin is modulated by diet-induced obesity and has direct actions on arcuate proopiomelanocortin neurons

por Roberts, Brandon L., Bennett, Baylin J., Bennett, Camdin M., Carroll, Julie M., Dalbøge, Louise S., Hall, Colin, Hassouneh, Wafa, Heppner, Kristy M., Kirigiti, Melissa A., Lindsley, Sarah R., Tennant, Katherine G., True, Cadence A., Whittle, Andrew, Wolf, Anitra C., Roberts, Charles T., Tang-Christensen, Mads, Sleeman, Mark W., Cowley, Michael A., Grove, Kevin L., Kievit, Paul
Publicado 2019

Fibroblast Growth Factor 21 Mediates Specific Glucagon Actions

por Habegger, Kirk M., Stemmer, Kerstin, Cheng, Christine, Müller, Timo D., Heppner, Kristy M., Ottaway, Nickki, Holland, Jenna, Hembree, Jazzminn L., Smiley, David, Gelfanov, Vasily, Krishna, Radha, Arafat, Ayman M., Konkar, Anish, Belli, Sara, Kapps, Martin, Woods, Stephen C., Hofmann, Susanna M., D’Alessio, David, Pfluger, Paul T., Perez-Tilve, Diego, Seeley, Randy J., Konishi, Morichika, Itoh, Nobuyujki, Kharitonenkov, Alexei, Spranger, Joachim, DiMarchi, Richard D., Tschöp, Matthias H.
Publicado 2013

Hypothalamic leptin action is mediated by histone deacetylase 5

por Kabra, Dhiraj G., Pfuhlmann, Katrin, García-Cáceres, Cristina, Schriever, Sonja C., Casquero García, Veronica, Kebede, Adam Fiseha, Fuente-Martin, Esther, Trivedi, Chitrang, Heppner, Kristy, Uhlenhaut, N. Henriette, Legutko, Beata, Kabra, Uma D., Gao, Yuanqing, Yi, Chun-Xia, Quarta, Carmelo, Clemmensen, Christoffer, Finan, Brian, Müller, Timo D., Meyer, Carola W., Paez-Pereda, Marcelo, Stemmer, Kerstin, Woods, Stephen C., Perez-Tilve, Diego, Schneider, Robert, Olson, Eric N., Tschöp, Matthias H., Pfluger, Paul T.
Publicado 2016

The orphan receptor Gpr83 regulates systemic energy metabolism via ghrelin-dependent and ghrelin-independent mechanisms

por Müller, Timo D., Müller, Anne, Yi, Chun-Xia, M Habegger, Kirk, Meyer, Carola W., Gaylinn, Bruce D., Finan, Brian, Heppner, Kristy, Trivedi, Chitrang, Bielohuby, Maximilian, Abplanalp, William, Meyer, Franziska, Piechowski, Carolin L., Pratzka, Juliane, Stemmer, Kerstin, Holland, Jenna, Hembree, Jazzmin, Bhardwaj, Nakul, Raver, Christine, Ottaway, Nickki, Krishna, Radha, Sah, Renu, Sallee, Floyd R., Woods, Stephen C., Perez-Tilve, Diego, Bidlingmaier, Martin, Thorner, Michael O., Krude, Heiko, Smiley, David, DiMarchi, Richard, Hofmann, Susanna, Pfluger, Paul T., Kleinau, Gunnar, Biebermann, Heike, Tschöp, Matthias H.
Publicado 2013