Sost Haploinsufficiency Provokes Peracute Lethal Cardiac Tamponade without Rescuing the Osteopenia in a Mouse Model of Excess Glucocorticoids

por Javaheri, Behzad, Herbert, Eleanor, Hopkinson, Mark, Al-Jazzar, Ahmed, Pitsillides, Andrew A.
Publicado 2019

CD9 identifies pancreatic cancer stem cells and modulates glutamine metabolism to fuel tumour growth

por Wang, Victoria M.-Y., Ferreira, Rute M. M., Almagro, Jorge, Evan, Theodore, Legrave, Nathalie, Zaw Thin, May, Frith, David, Carvalho, Joana, Barry, David J., Snijders, Ambrosius P., Herbert, Eleanor, Nye, Emma L., MacRae, James I., Behrens, Axel
Publicado 2019

RAC1(P29S) Induces a Mesenchymal Phenotypic Switch via Serum Response Factor to Promote Melanoma Development and Therapy Resistance

por Lionarons, Daniël A., Hancock, David C., Rana, Sareena, East, Philip, Moore, Christopher, Murillo, Miguel M., Carvalho, Joana, Spencer-Dene, Bradley, Herbert, Eleanor, Stamp, Gordon, Damry, Djamil, Calado, Dinis P., Rosewell, Ian, Fritsch, Ralph, Neubig, Richard R., Molina-Arcas, Miriam, Downward, Julian
Publicado 2019

Mouse transcriptome reveals potential signatures of protection and pathogenesis in human tuberculosis

por Moreira-Teixeira, Lúcia, Tabone, Olivier, Graham, Christine M., Singhania, Akul, Stavropoulos, Evangelos, Redford, Paul S., Chakravarty, Probir, Priestnall, Simon L., Suarez-Bonnet, Alejandro, Herbert, Eleanor, Mayer-Barber, Katrin D., Sher, Alan, Fonseca, Kaori L., Sousa, Jeremy, Cá, Baltazar, Verma, Raman, Haldar, Pranabashis, Saraiva, Margarida, O’Garra, Anne
Publicado 2020

Type I IFN exacerbates disease in tuberculosis-susceptible mice by inducing neutrophil-mediated lung inflammation and NETosis

por Moreira-Teixeira, Lúcia, Stimpson, Philippa J., Stavropoulos, Evangelos, Hadebe, Sabelo, Chakravarty, Probir, Ioannou, Marianna, Aramburu, Iker Valle, Herbert, Eleanor, Priestnall, Simon L., Suarez-Bonnet, Alejandro, Sousa, Jeremy, Fonseca, Kaori L., Wang, Qian, Vashakidze, Sergo, Rodríguez-Martínez, Paula, Vilaplana, Cristina, Saraiva, Margarida, Papayannopoulos, Venizelos, O’Garra, Anne
Publicado 2020

The occurrence of tarsal injuries in male mice of C57BL/6N substrains in multiple international mouse facilities

por Herbert, Eleanor, Stewart, Michelle, Hutchison, Marie, Flenniken, Ann M., Qu, Dawei, Nutter, Lauryl M. J., McKerlie, Colin, Hobson, Liane, Kick, Brenda, Lyons, Bonnie, Wiegand, Jean-Paul, Doty, Rosalinda, Aguilar-Pimentel, Juan Antonio, Hrabe de Angelis, Martin, Dickinson, Mary, Seavitt, John, White, Jacqueline K., Scudamore, Cheryl L., Wells, Sara
Publicado 2020

A role for NPY-NPY2R signaling in albuminuric kidney disease

por Lay, Abigail C., Barrington, A. Fern, Hurcombe, Jenny A., Ramnath, Raina D., Graham, Mark, Lewis, Philip A., Wilson, Marieangela C., Heesom, Kate J., Butler, Matthew J., Perrett, Rebecca M., Neal, Chris R., Herbert, Eleanor, Mountjoy, Edward, Atan, Denize, Nair, Viji, Ju, Wenjun, Nelson, Robert G., Kretzler, Matthias, Satchell, Simon C., McArdle, Craig A., Welsh, Gavin I., Coward, Richard J. M.
Publicado 2020

PKN2 deficiency leads both to prenatal ‘congenital’ cardiomyopathy and defective angiotensin II stress responses

por Marshall, Jacqueline J.T., Cull, Joshua J., Alharbi, Hajed O., Zaw Thin, May, Cooper, Susanna T.E., Barrington, Christopher, Vanyai, Hannah, Snoeks, Thomas, Siow, Bernard, Suáarez-Bonnet, Alejandro, Herbert, Eleanor, Stuckey, Daniel J., Cameron, Angus J.M., Prin, Fabrice, Cook, Andrew C., Priestnall, Simon L., Chotani, Sonia, Rackham, Owen J. L., Meijles, Daniel N., Mohun, Tim, Clerk, Angela, Parker, Peter J.
Publicado 2022

Comprehensive phenotypic analysis of the Dp1Tyb mouse strain reveals a broad range of Down syndrome-related phenotypes

por Lana-Elola, Eva, Cater, Heather, Watson-Scales, Sheona, Greenaway, Simon, Müller-Winkler, Jennifer, Gibbins, Dorota, Nemes, Mihaela, Slender, Amy, Hough, Tertius, Keskivali-Bond, Piia, Scudamore, Cheryl L., Herbert, Eleanor, Banks, Gareth T., Mobbs, Helene, Canonica, Tara, Tosh, Justin, Noy, Suzanna, Llorian, Miriam, Nolan, Patrick M., Griffin, Julian L., Good, Mark, Simon, Michelle, Mallon, Ann-Marie, Wells, Sara, Fisher, Elizabeth M. C., Tybulewicz, Victor L. J.
Publicado 2021

Transcriptional profiling unveils type I and II interferon networks in blood and tissues across diseases

por Singhania, Akul, Graham, Christine M., Gabryšová, Leona, Moreira-Teixeira, Lúcia, Stavropoulos, Evangelos, Pitt, Jonathan M., Chakravarty, Probir, Warnatsch, Annika, Branchett, William J., Conejero, Laura, Lin, Jing-Wen, Davidson, Sophia, Wilson, Mark S., Bancroft, Gregory, Langhorne, Jean, Frickel, Eva, Sesay, Abdul K., Priestnall, Simon L., Herbert, Eleanor, Ioannou, Marianna, Wang, Qian, Humphreys, Ian R., Dodd, Jonathan, Openshaw, Peter J. M., Mayer-Barber, Katrin D., Jankovic, Dragana, Sher, Alan, Lloyd, Clare M., Baldwin, Nicole, Chaussabel, Damien, Papayannopoulos, Venizelos, Wack, Andreas, Banchereau, Jacques F., Pascual, Virginia M., O’Garra, Anne
Publicado 2019