Splicing factor SRSF1 is essential for CD8 T cell function and host antigen-specific viral immunity

por Juarez, Ignacio, Su, Shi, Herbert, Zachary T., Teijaro, John R., Moulton, Vaishali R.
Publicado 2022

Intra- and extra-cellular environments contribute to the fate of HIV-1 infection

por Ratnapriya, Sneha, Harris, Miranda, Chov, Angela, Herbert, Zachary T., Vrbanac, Vladimir, Deruaz, Maud, Achuthan, Vasudevan, Engelman, Alan N., Sodroski, Joseph, Herschhorn, Alon
Publicado 2021

Ultrasensitive profiling of UV-induced mutations identifies thousands of subclinical facial tumors in tuberous sclerosis complex

por Klonowska, Katarzyna, Grevelink, Joannes M., Giannikou, Krinio, Ogorek, Barbara A., Herbert, Zachary T., Thorner, Aaron R., Darling, Thomas N., Moss, Joel, Kwiatkowski, David J.
Publicado 2022

Uncovering transcriptomic landscape alterations of CAN-2409 in in vitro and in vivo glioma models

por Koch, Marilin S., Zdioruk, Mykola, Nowicki, Michal O., Hoetker, Michael S., Herbert, Zachary T., Barone, Francesca, Tak, Paul P., Chiocca, E. Antonio, Tabatabai, Ghazaleh, Lawler, Sean E.
Publicado 2023

Telomerase reactivation induces progression of mouse Braf(V600E)-driven thyroid cancers without telomere lengthening

por Landa, Iñigo, Thornton, Caitlin EM, Xu, Bin, Haase, Jacob, Krishnamoorthy, Gnana P., Hao, Jingzhu, Knauf, Jeffrey A, Herbert, Zachary T, Blasco, María A, Ghossein, Ronald, Fagin, James A
Publicado 2023

IL1R1 is required for celastrol’s leptin sensitization and anti-obesity effects

por Feng, Xudong, Guan, Dongxian, Auen, Thomas, Choi, Jae Won, Salazar Hernández, Mario Andrés, Lee, Jaemin, Chun, Hyonho, Faruk, Farhana, Kaplun, Esther, Herbert, Zachary, Copps, Kyle D., Ozcan, Umut
Publicado 2019

Impairment of gamma-glutamyl transferase 1 activity in the metabolic pathogenesis of chromophobe renal cell carcinoma

por Priolo, Carmen, Khabibullin, Damir, Reznik, Ed, Filippakis, Harilaos, Ogórek, Barbara, Kavanagh, Taylor R., Nijmeh, Julie, Herbert, Zachary T., Asara, John M., Kwiatkowski, David J., Wu, Chin-Lee, Henske, Elizabeth P.
Publicado 2018

VIPER: Visualization Pipeline for RNA-seq, a Snakemake workflow for efficient and complete RNA-seq analysis

por Cornwell, MacIntosh, Vangala, Mahesh, Taing, Len, Herbert, Zachary, Köster, Johannes, Li, Bo, Sun, Hanfei, Li, Taiwen, Zhang, Jian, Qiu, Xintao, Pun, Matthew, Jeselsohn, Rinath, Brown, Myles, Liu, X. Shirley, Long, Henry W.
Publicado 2018

Heme oxygenase-1 mitigates liver injury and fibrosis via modulation of LNX1/Notch1 pathway in myeloid cells

por Canesin, Giacomo, Feldbrügge, Linda, Wei, Guangyan, Janovicova, Lubica, Janikova, Monika, Csizmadia, Eva, Ariffin, Juliana, Hedblom, Andreas, Herbert, Zachary T., Robson, Simon C., Celec, Peter, Swanson, Kenneth D., Nasser, Imad, Popov, Yury V., Wegiel, Barbara
Publicado 2022

Astrocyte-neuron crosstalk through Hedgehog signaling mediates cortical synapse development

por Xie, Yajun, Kuan, Aaron T., Wang, Wengang, Herbert, Zachary T., Mosto, Olivia, Olukoya, Olubusola, Adam, Manal, Vu, Steve, Kim, Minsu, Tran, Diana, Gómez, Nicolás, Charpentier, Claire, Sorour, Ingie, Lacey, Tiara E., Tolstorukov, Michael Y., Sabatini, Bernardo L., Lee, Wei-Chung Allen, Harwell, Corey C.
Publicado 2022

Cross-site comparison of ribosomal depletion kits for Illumina RNAseq library construction

por Herbert, Zachary T., Kershner, Jamie P., Butty, Vincent L., Thimmapuram, Jyothi, Choudhari, Sulbha, Alekseyev, Yuriy O., Fan, Jun, Podnar, Jessica W., Wilcox, Edward, Gipson, Jenny, Gillaspy, Allison, Jepsen, Kristen, BonDurant, Sandra Splinter, Morris, Krystalynne, Berkeley, Maura, LeClerc, Ashley, Simpson, Stephen D., Sommerville, Gary, Grimmett, Leslie, Adams, Marie, Levine, Stuart S.
Publicado 2018

The KDM5A/RBP2 histone demethylase represses NOTCH signaling to sustain neuroendocrine differentiation and promote small cell lung cancer tumorigenesis

por Oser, Matthew G., Sabet, Amin H., Gao, Wenhua, Chakraborty, Abhishek A., Schinzel, Anna C., Jennings, Rebecca B., Fonseca, Raquel, Bonal, Dennis M., Booker, Matthew A., Flaifel, Abdallah, Novak, Jesse S., Christensen, Camilla L., Zhang, Hua, Herbert, Zachary T., Tolstorukov, Michael Y., Buss, Elizabeth J., Wong, Kwok-Kin, Bronson, Roderick T., Nguyen, Quang-De, Signoretti, Sabina, Kaelin, William G.
Publicado 2019

A distinct core regulatory module enforces oncogene expression in KMT2A-rearranged leukemia

por Harada, Taku, Heshmati, Yaser, Kalfon, Jérémie, Perez, Monika W., Xavier Ferrucio, Juliana, Ewers, Jazmin, Hubbell Engler, Benjamin, Kossenkov, Andrew, Ellegast, Jana M., Yi, Joanna S., Bowker, Allyson, Zhu, Qian, Eagle, Kenneth, Liu, Tianxin, Kai, Yan, Dempster, Joshua M., Kugener, Guillaume, Wickramasinghe, Jayamanna, Herbert, Zachary T., Li, Charles H., Vrabič Koren, Jošt, Weinstock, David M., Paralkar, Vikram R., Nabet, Behnam, Lin, Charles Y., Dharia, Neekesh V., Stegmaier, Kimberly, Orkin, Stuart H., Pimkin, Maxim
Publicado 2022

Mitogenic and progenitor gene programmes in single pilocytic astrocytoma cells

por Reitman, Zachary J., Paolella, Brenton R., Bergthold, Guillaume, Pelton, Kristine, Becker, Sarah, Jones, Robert, Sinai, Claire E., Malkin, Hayley, Huang, Ying, Grimmet, Leslie, Herbert, Zachary T., Sun, Yu, Weatherbee, Jessica L., Alberta, John A., Daley, John F., Rozenblatt-Rosen, Orit, Condurat, Alexandra L., Qian, Kenin, Khadka, Prasidda, Segal, Rosalind A., Haas-Kogan, Daphne, Filbin, Mariella G., Suva, Mario L., Regev, Aviv, Stiles, Charles D., Kieran, Mark W., Goumnerova, Liliana, Ligon, Keith L., Shalek, Alex K., Bandopadhayay, Pratiti, Beroukhim, Rameen
Publicado 2019

Multiomic analysis identifies CPT1A as a potential therapeutic target in platinum-refractory, high-grade serous ovarian cancer

por Huang, Dongqing, Chowdhury, Shrabanti, Wang, Hong, Savage, Sara R., Ivey, Richard G., Kennedy, Jacob J., Whiteaker, Jeffrey R., Lin, Chenwei, Hou, Xiaonan, Oberg, Ann L., Larson, Melissa C., Eskandari, Najmeh, Delisi, Davide A., Gentile, Saverio, Huntoon, Catherine J., Voytovich, Uliana J., Shire, Zahra J., Yu, Qing, Gygi, Steven P., Hoofnagle, Andrew N., Herbert, Zachary T., Lorentzen, Travis D., Calinawan, Anna, Karnitz, Larry M., Weroha, S. John, Kaufmann, Scott H., Zhang, Bing, Wang, Pei, Birrer, Michael J., Paulovich, Amanda G.
Publicado 2021

Proteogenomic analysis of chemo-refractory high-grade serous ovarian cancer

por Chowdhury, Shrabanti, Kennedy, Jacob J., Ivey, Richard G., Murillo, Oscar D., Hosseini, Noshad, Song, Xiaoyu, Petralia, Francesca, Calinawan, Anna, Savage, Sara R., Berry, Anna B., Reva, Boris, Ozbek, Umut, Krek, Azra, Ma, Weiping, da Veiga Leprevost, Felipe, Ji, Jiayi, Yoo, Seungyeul, Lin, Chenwei, Voytovich, Uliana J., Huang, Yajue, Lee, Sun-Hee, Bergan, Lindsay, Lorentzen, Travis D., Mesri, Mehdi, Rodriguez, Henry, Hoofnagle, Andrew N., Herbert, Zachary T., Nesvizhskii, Alexey I., Zhang, Bing, Whiteaker, Jeffrey R., Fenyo, David, McKerrow, Wilson, Wang, Joshua, Schürer, Stephan C., Stathias, Vasileios, Chen, X. Steven, Barcellos-Hoff, Mary Helen, Starr, Timothy K., Winterhoff, Boris J., Nelson, Andrew C., Mok, Samuel C., Kaufmann, Scott H., Drescher, Charles, Cieslik, Marcin, Wang, Pei, Birrer, Michael J., Paulovich, Amanda G.
Publicado 2023