A Randomized Phase I Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Recombinant Erwinia Asparaginase (JZP‐458) in Healthy Adult Volunteers

por Lin, Tong, Hernandez‐Illas, Martha, Rey, Andres, Jenkins, Jack, Chandula, Reddy, Silverman, Jeffrey A., Choi, Mi Rim
Publicado 2021

Safety, Tolerability, and Pharmacokinetics of MEDI4893, an Investigational, Extended-Half-Life, Anti-Staphylococcus aureus Alpha-Toxin Human Monoclonal Antibody, in Healthy Adults

por Yu, Xiang-Qing, Robbie, Gabriel J., Wu, Yuling, Esser, Mark T., Jensen, Kathryn, Schwartz, Howard I., Bellamy, Terramika, Hernandez-Illas, Martha, Jafri, Hasan S.
Publicado 2016

OR12-2 Inhibition of Basal and ACTH-stimulated Cortisol Secretion in Humans Using an Oral Nonpeptide ACTH Antagonist (CRN04894)

por Betz, Stephen, Ferrara-Cook, Christine, Hernandez-Illas, Martha, Luo, Rosa, Madan, Ajay, Miller, Stephanie, Struthers, Scott, Trainer, Peter, Wang, Yang, Krasner, Alan
Publicado 2022

Pharmacodynamic and pharmacokinetic effects and safety of verinurad in combination with allopurinol in adults with gout: a phase IIa, open-label study

por Fleischmann, Roy, Winkle, Peter, Miner, Jeffrey N, Yan, Xiaohong, Hicks, Liz, Valdez, Shakti, Hall, Jesse, Liu, Sha, Shen, Zancong, Gillen, Michael, Hernandez-Illas, Martha
Publicado 2018

Pharmacodynamic and pharmacokinetic effects and safety of verinurad in combination with febuxostat in adults with gout: a phase IIa, open-label study

por Fleischmann, Roy, Winkle, Peter, Hall, Jesse, Valdez, Shakti, Liu, Sha, Yan, Xiaohong, Hicks, Liz, Lee, Caroline, Miner, Jeffrey N, Gillen, Michael, Hernandez-Illas, Martha
Publicado 2018

1557. Population Pharmacokinetics of Suvratoxumab (MEDI4893), an Extended Half-life Staphylococcus aureus Alpha Toxin-Neutralizing Human Monoclonal Antibody, in Healthy Adults and...

por Pierre, Vadryn, Francois, Bruno, Hernandez-Illas, Martha, Sánchez Garcia, Miguel, Wu, Yuling, Eggimann, Philippe, Laterre, Pierre-Francois, Huberlant, Vincent, Viña, Lucia, Boulain, Thierry, Ruzin, Alexey, Bretonnière, Cédric, Pugin, Jerome, Trenado Álvarez, José, Bellamy, Terramika, Shoemaker, Kathryn, Ali, Omar, Lee, Nancy, Dequin, Pierre-Francois, Jafri, Hasan S, Roskos, Lorin, Colbert, Susan, Khan, Anis
Publicado 2019

Safety and immunogenicity of intramuscular, single-dose V590 (rVSV-SARS-CoV-2 Vaccine) in healthy adults: Results from a phase 1 randomised, double-blind, placebo-controlled, dose-...

por Robbins, Jonathan A., Tait, Dereck, Huang, Qinlei, Dubey, Sheri, Crumley, Tami, Cote, Josee, Luk, Julie, Sachs, Jeffrey R., Rutkowski, Kathryn, Park, Harriet, Schwab, Robert, Howitt, William Joseph, Rondon, Juan Carlos, Hernandez-Illas, Martha, O'Reilly, Terry, Smith, William, Simon, Jakub, Hardalo, Cathy, Zhao, Xuemei, Wnek, Richard, Cope, Alethea, Lai, Eseng, Annunziato, Paula, Guris, Dalya, Stoch, S. Aubrey
Publicado 2022