In Vitro and In Vivo Evaluation of a Small-Molecule APJ (Apelin Receptor) Agonist, BMS-986224, as a Potential Treatment for Heart Failure

por Gargalovic, Peter, Wong, Pancras, Onorato, Joelle, Finlay, Heather, Wang, Tao, Yan, Mujing, Crain, Earl, St-Onge, Stéphane, Héroux, Madeleine, Bouvier, Michel, Xu, Carrie, Chen, Xue-Qing, Generaux, Claudia, Lawrence, Michael, Wexler, Ruth, Gordon, David
Publicado 2021

Effector membrane translocation biosensors reveal G protein and βarrestin coupling profiles of 100 therapeutically relevant GPCRs

por Avet, Charlotte, Mancini, Arturo, Breton, Billy, Le Gouill, Christian, Hauser, Alexander S, Normand, Claire, Kobayashi, Hiroyuki, Gross, Florence, Hogue, Mireille, Lukasheva, Viktoriya, St-Onge, Stéphane, Carrier, Marilyn, Héroux, Madeleine, Morissette, Sandra, Fauman, Eric B, Fortin, Jean-Philippe, Schann, Stephan, Leroy, Xavier, Gloriam, David E, Bouvier, Michel
Publicado 2022

Allosteric modulation of metabotropic glutamate receptor 4 activates IDO1-dependent, immunoregulatory signaling in dendritic cells

por Volpi, Claudia, Mondanelli, Giada, Pallotta, Maria T., Vacca, Carmine, Iacono, Alberta, Gargaro, Marco, Albini, Elisa, Bianchi, Roberta, Belladonna, Maria L., Celanire, Sylvain, Mordant, Céline, Heroux, Madeleine, Royer-Urios, Isabelle, Schneider, Manfred, Vitte, Pierre-Alain, Cacquevel, Mathias, Galibert, Laurent, Poli, Sonia-Maria, Solari, Aldo, Bicciato, Silvio, Calvitti, Mario, Antognelli, Cinzia, Puccetti, Paolo, Orabona, Ciriana, Fallarino, Francesca, Grohmann, Ursula
Publicado 2016

Preservation of Post-Infarction Cardiac Structure and Function via Long-Term Oral Formyl Peptide Receptor Agonist Treatment

por García, Ricardo A., Ito, Bruce R., Lupisella, John A., Carson, Nancy A., Hsu, Mei-Yin, Fernando, Gayani, Heroux, Madeleine, Bouvier, Michel, Dierks, Elizabeth, Kick, Ellen K., Gordon, David A., Chen, Jian, Mintier, Gabe, Carrier, Marilyn, St-Onge, Stéphane, Shah, Himanshu, Towne, Jordan, Bucardo, Marcela Sotelo, Ma, Xiuying, Ryan, Carol S., Wurtz, Nicholas R., Ostrowski, Jacek, Villarreal, Francisco J.
Publicado 2019

Selective FPR2 Agonism Promotes a Proresolution Macrophage Phenotype and Improves Cardiac Structure-Function Post Myocardial Infarction

por García, Ricardo A., Lupisella, John A., Ito, Bruce R., Hsu, Mei-Yin, Fernando, Gayani, Carson, Nancy L., Allocco, John J., Ryan, Carol S., Zhang, Rongan, Wang, Zhaoqing, Heroux, Madeleine, Carrier, Marilyn, St.-Onge, Stéphane, Bouvier, Michel, Dudhgaonkar, Shailesh, Nagar, Jignesh, Bustamante-Pozo, Moises M., Garate-Carrillo, Alejandra, Chen, Jian, Ma, Xiuying, Search, Debra J., Dierks, Elizabeth A., Kick, Ellen K., Wexler, Ruth R., Gordon, David A., Ostrowski, Jacek, Wurtz, Nicholas R., Villarreal, Francisco
Publicado 2021