Tampering with springs: phosphorylation of titin affecting the mechanical function of cardiomyocytes

por Hamdani, Nazha, Herwig, Melissa, Linke, Wolfgang A.
Publicado 2017

Molecular and structural transition mechanisms in long‐term volume overload

por Mohamed, Belal A., Schnelle, Moritz, Khadjeh, Sara, Lbik, Dawid, Herwig, Melissa, Linke, Wolfgang A., Hasenfuss, Gerd, Toischer, Karl
Publicado 2015

Linagliptin prevents left ventricular stiffening by reducing titin cleavage and hypophosphorylation

por Cuijpers, Ilona, Papageorgiou, Anna‐Pia, Carai, Paolo, Herwig, Melissa, Mügge, Andreas, Klein, Thomas, Hamdani, Nazha, Jones, Elizabeth A. V., Heymans, Stephane
Publicado 2020

Oxidative stress and inflammation distinctly drive molecular mechanisms of diastolic dysfunction and remodeling in female and male heart failure with preserved ejection fraction ra...

por Zhazykbayeva, Saltanat, Hassoun, Roua, Herwig, Melissa, Budde, Heidi, Kovács, Árpád, Mannherz, Hans Georg, El-Battrawy, Ibrahim, Tóth, Attila, Schmidt, Wolfgang E., Mügge, Andreas, Hamdani, Nazha
Publicado 2023

C-type natriuretic peptide moderates titin-based cardiomyocyte stiffness

por Michel, Konstanze, Herwig, Melissa, Werner, Franziska, Špiranec Spes, Katarina, Abeßer, Marco, Schuh, Kai, Dabral, Swati, Mügge, Andreas, Baba, Hideo A., Skryabin, Boris V., Hamdani, Nazha, Kuhn, Michaela
Publicado 2020

Modulation of Titin-Based Stiffness in Hypertrophic Cardiomyopathy via Protein Kinase D

por Herwig, Melissa, Kolijn, Detmar, Lódi, Mária, Hölper, Soraya, Kovács, Árpád, Papp, Zoltán, Jaquet, Kornelia, Haldenwang, Peter, Dos Remedios, Cris, Reusch, Peter H., Mügge, Andreas, Krüger, Marcus, Fielitz, Jens, Linke, Wolfgang A., Hamdani, Nazha
Publicado 2020

Altered Cellular Protein Quality Control System Modulates Cardiomyocyte Function in Volume Overload-Induced Hypertrophy

por Gömöri, Kamilla, Herwig, Melissa, Hassoun, Roua, Budde, Heidi, Mostafi, Nusratul, Delalat, Simin, Modi, Suvasini, Begovic, Merima, Szabados, Tamara, Pipis, Judit, Farkas-Morvay, Nikolett, Leprán, István, Kovács, Árpád, Mügge, Andreas, Ferdinandy, Péter, Görbe, Anikó, Bencsik, Péter, Hamdani, Nazha
Publicado 2022

Enhanced Cardiomyocyte Function in Hypertensive Rats With Diastolic Dysfunction and Human Heart Failure Patients After Acute Treatment With Soluble Guanylyl Cyclase (sGC) Activator

por Kolijn, Detmar, Kovács, Árpád, Herwig, Melissa, Lódi, Mária, Sieme, Marcel, Alhaj, Abdulatif, Sandner, Peter, Papp, Zoltán, Reusch, Peter H., Haldenwang, Peter, Falcão-Pires, Ines, Linke, Wolfgang A., Jaquet, Kornelia, Van Linthout, Sophie, Mügge, Andreas, Tschöpe, Carsten, Hamdani, Nazha
Publicado 2020

Interventricular Differences of Signaling Pathways-Mediated Regulation of Cardiomyocyte Function in Response to High Oxidative Stress in the Post-Ischemic Failing Rat Heart

por Kovács, Árpád, Herwig, Melissa, Budde, Heidi, Delalat, Simin, Kolijn, Detmar, Bódi, Beáta, Hassoun, Roua, Tangos, Melina, Zhazykbayeva, Saltanat, Balogh, Ágnes, Czuriga, Dániel, Van Linthout, Sophie, Tschöpe, Carsten, Dhalla, Naranjan S., Mügge, Andreas, Tóth, Attila, Papp, Zoltán, Barta, Judit, Hamdani, Nazha
Publicado 2021

Ca2+/calmodulin‐dependent protein kinase II and protein kinase G oxidation contributes to impaired sarcomeric proteins in hypertrophy model

por Gömöri, Kamilla, Herwig, Melissa, Budde, Heidi, Hassoun, Roua, Mostafi, Nusratul, Zhazykbayeva, Saltanat, Sieme, Marcel, Modi, Suvasini, Szabados, Tamara, Pipis, Judit, Farkas‐Morvay, Nikolett, Leprán, István, Ágoston, Gergely, Baczkó, István, Kovács, Árpád, Mügge, Andreas, Ferdinandy, Péter, Görbe, Anikó, Bencsik, Péter, Hamdani, Nazha
Publicado 2022

The Interplay between S-Glutathionylation and Phosphorylation of Cardiac Troponin I and Myosin Binding Protein C in End-Stage Human Failing Hearts

por Budde, Heidi, Hassoun, Roua, Tangos, Melina, Zhazykbayeva, Saltanat, Herwig, Melissa, Varatnitskaya, Marharyta, Sieme, Marcel, Delalat, Simin, Sultana, Innas, Kolijn, Detmar, Gömöri, Kamilla, Jarkas, Muhammad, Lódi, Mária, Jaquet, Kornelia, Kovács, Árpád, Mannherz, Hans Georg, Sequeira, Vasco, Mügge, Andreas, Leichert, Lars I., Sossalla, Samuel, Hamdani, Nazha
Publicado 2021

Effects of Atrial Fibrillation on the Human Ventricle

por Pabel, Steffen, Knierim, Maria, Stehle, Thea, Alebrand, Felix, Paulus, Michael, Sieme, Marcel, Herwig, Melissa, Barsch, Friedrich, Körtl, Thomas, Pöppl, Arnold, Wenner, Brisca, Ljubojevic-Holzer, Senka, Molina, Cristina E., Dybkova, Nataliya, Camboni, Daniele, Fischer, Thomas H., Sedej, Simon, Scherr, Daniel, Schmid, Christof, Brochhausen, Christoph, Hasenfuß, Gerd, Maier, Lars S., Hamdani, Nazha, Streckfuss-Bömeke, Katrin, Sossalla, Samuel
Publicado 2022

SARS-CoV-2 infects human cardiomyocytes promoted by inflammation and oxidative stress

por Tangos, Melina, Budde, Heidi, Kolijn, Detmar, Sieme, Marcel, Zhazykbayeva, Saltanat, Lódi, Mária, Herwig, Melissa, Gömöri, Kamilla, Hassoun, Roua, Robinson, Emma Louise, Meister, Toni Luise, Jaquet, Kornelia, Kovács, Árpád, Mustroph, Julian, Evert, Katja, Babel, Nina, Fagyas, Miklós, Lindner, Diana, Püschel, Klaus, Westermann, Dirk, Mannherz, Hans Georg, Paneni, Francesco, Pfaender, Stephanie, Tóth, Attila, Mügge, Andreas, Sossalla, Samuel, Hamdani, Nazha
Publicado 2022