Brain-penetrant heat shock protein amplifier arimoclomol enhances GCase activity in in vitro Gaucher disease models

por Hettinghouse, Aubryanna, Liu, Chuan-ju
Publicado 2018

Progranulin acts as a shared chaperone and regulates multiple lysosomal enzymes

por Jian, Jinlong, Hettinghouse, Aubryanna, Liu, Chuan-ju
Publicado 2017

Atsttrin Promotes Cartilage Repair Primarily Through TNFR2-Akt Pathway

por Wei, Jianlu, Wang, Kaidi, Hettinghouse, Aubryanna, Liu, Chuanju
Publicado 2020

Cytosolic Phospholipase A2 Is Required for Fexofenadine’s Therapeutic Effects against Inflammatory Bowel Disease in Mice

por Zhao, Xiangli, Liu, Ronghan, Chen, Yuehong, Hettinghouse, Aubryanna, Liu, Chuanju
Publicado 2021

RNA-Seq analysis of interferon inducible p204-mediated network in anti-tumor immunity

por Jian, Jinlong, Wei, Wei, Yin, Guowei, Hettinghouse, Aubryanna, Liu, Chuanju, Shi, Yongxiang
Publicado 2018

Progranulin derivative Atsttrin protects against early osteoarthritis in mouse and rat models

por Wei, Jian-lu, Fu, Wenyu, Ding, Yuan-jing, Hettinghouse, Aubryanna, Lendhey, Matin, Schwarzkopf, Ran, Kennedy, Oran D., Liu, Chuan-ju
Publicado 2017

Penfluridol targets acid sphingomyelinase to inhibit TNF signaling and is therapeutic against inflammatory autoimmune diseases

por Chen, Yue-hong, Liu, Rong-han, Cui, Ya-zhou, Hettinghouse, Aubryanna, Fu, Wen-yu, Zhang, Lei, Zhang, Chen, Liu, Chuan-ju
Publicado 2022

Progranulin deficiency exacerbates spinal cord injury by promoting neuroinflammation and cell apoptosis in mice

por Wang, Chao, Zhang, Lu, Ndong, Jean De La Croix, Hettinghouse, Aubryanna, Sun, Guodong, Chen, Changhong, Zhang, Chen, Liu, Ronghan, Liu, Chuan-ju
Publicado 2019

Repurposing FDA-approved drugs for SARS-CoV-2 through an ELISA-based screening for the inhibition of RBD/ACE2 interaction

por Fu, Wenyu, Chen, Yujianan, Wang, Kaidi, Hettinghouse, Aubryanna, Hu, Wenhuo, Wang, Jing-Quan, Lei, Zi-Ning, Chen, Zhe-Sheng, Stapleford, Kenneth A., Liu, Chuan-ju
Publicado 2020

Progranulin Recruits HSP70 to β-Glucocerebrosidase and Is Therapeutic Against Gaucher Disease

por Jian, Jinlong, Tian, Qing-Yun, Hettinghouse, Aubryanna, Zhao, Shuai, Liu, Helen, Wei, Jianlu, Grunig, Gabriele, Zhang, Wujuan, Setchell, Kenneth D.R., Sun, Ying, Overkleeft, Herman S., Chan, Gerald L., Liu, Chuan-ju
Publicado 2016

p204 Is Required for Canonical Lipopolysaccharide-induced TLR4 Signaling in Mice

por Yi, Young-Su, Jian, Jinlong, Gonzalez-Gugel, Elena, Shi, Yong-Xiang, Tian, Qingyun, Fu, Wenyu, Hettinghouse, Aubryanna, Song, Wenhao, Liu, Ronghan, He, Michun, Qi, Huabing, Yang, Jing, Du, Xiaolan, Xiao, GuoZhi, Chen, Lin, Liu, Chuan-ju
Publicado 2018