Review of WADA Prohibited Substances: Limited Evidence for Performance-Enhancing Effects

por Heuberger, Jules A. A. C., Cohen, Adam F.
Publicado 2018

Futility of current urine salbutamol doping control

por Heuberger, Jules A. A. C., van Dijkman, Sven C., Cohen, Adam F.
Publicado 2018

Targeting for Success: Demonstrating Proof-of-Concept with Mechanistic Early Phase Clinical Pharmacology Studies for Disease-Modification in Neurodegenerative Disorders

por Vissers, Maurits F. J. M., Heuberger, Jules A. A. C., Groeneveld, Geert Jan
Publicado 2021

Pharmacokinetic Modeling and Dose Selection in a Randomized, Double-Blind, Placebo-Controlled Trial of a Human Recombinant Alkaline Phosphatase in Healthy Volunteers

por Peters, Esther, Heuberger, Jules A. A. C., Tiessen, Renger, van Elsas, Andrea, Masereeuw, Rosalinde, Arend, Jacques, Stevens, Jasper, Pickkers, Peter
Publicado 2016

Repeatability and predictive value of lactate threshold concepts in endurance sports

por Heuberger, Jules A. A. C., Gal, Pim, Stuurman, Frederik E., de Muinck Keizer, Wouter A. S., Mejia Miranda, Yuri, Cohen, Adam F.
Publicado 2018

Muscle velocity recovery cycles as pharmacodynamic biomarker: Effects of mexiletine in a randomized double‐blind placebo‐controlled cross‐over study

por Ruijs, Titia Q., Koopmans, Ingrid W., de Kam, Marieke L., Tannemaat, Martijn R., Groeneveld, Geert Jan, Heuberger, Jules A. A. C.
Publicado 2022

Recombinant human erythropoietin does not affect several microvascular parameters in well‐trained cyclists

por Birkhoff, Willem A. J., Heuberger, Jules A. A. C., Post, Titiaan E., Gal, Pim, Stuurman, Frederik E., Burggraaf, Jacobus, Cohen, Adam F.
Publicado 2018

A leucine‐rich repeat kinase 2 (LRRK2) pathway biomarker characterization study in patients with Parkinson's disease with and without LRRK2 mutations and healthy controls

por Vissers, Maurits F. J. M., Troyer, Matthew D., Thijssen, Eva, Pereira, Diana R., Heuberger, | Jules A. A. C., Groeneveld, Geert Jan, Huntwork‐Rodriguez, Sarah
Publicado 2023

Good Clinical Trials by removing defensive interpretation of Good Clinical Practice guidelines

por den Heijer, Jonas M., Heuberger, Jules A. A. C., Hijma, Hemme, Kruithof, Annelieke C., van Smeden, Jeroen, Groeneveld, Geert Jan, Burggraaf, Jacobus, Cohen, Adam
Publicado 2021

Effects of Mexiletine and Lacosamide on Nerve Excitability in Healthy Subjects: A Randomized, Double‐Blind, Placebo‐Controlled, Crossover Study

por Ruijs, Titia Q., Koopmans, Ingrid W., de Kam, Marieke L., van Esdonk, Michiel J., Koltzenburg, Martin, Groeneveld, Geert Jan, Heuberger, Jules A.A.C.
Publicado 2022

Acute retigabine‐induced effects on myelinated motor axons in amyotrophic lateral sclerosis

por Sleutjes, Boudewijn T. H. M., Stikvoort García, Diederik J. L., Kovalchuk, Maria O., Heuberger, Jules A. A. C., Groeneveld, Geert Jan, Franssen, Hessel, van den Berg, Leonard H.
Publicado 2022

Transcranial magnetic stimulation as biomarker of excitability in drug development: A randomized, double‐blind, placebo‐controlled, cross‐over study

por Ruijs, Titia Q., Heuberger, Jules A. A. C., de Goede, Annika A., Ziagkos, Dimitrios, Otto, Marije E., Doll, Robert J., van Putten, Michel J. A. M., Groeneveld, Geert Jan
Publicado 2022

Sensitivity and specificity of detection methods for erythropoietin doping in cyclists

por Heuberger, Jules A.A.C., van Eenoo, Peter, Rotmans, Joris I., Gal, Pim, Stuurman, Frederik E., Post, Titiaan E., Daniels, Johannes M.A., Ram, Herman, de Hon, Olivier, Burggraaf, Jacobus, Cohen, Adam F.
Publicado 2019

Effect of sustained high buprenorphine plasma concentrations on fentanyl-induced respiratory depression: A placebo-controlled crossover study in healthy volunteers and opioid-toler...

por Moss, Laurence M., Algera, Marijke Hyke, Dobbins, Robert, Gray, Frank, Strafford, Stephanie, Heath, Amy, van Velzen, Monique, Heuberger, Jules A. A. C., Niesters, Marieke, Olofsen, Erik, Laffont, Celine M., Dahan, Albert, Groeneveld, Geert Jan
Publicado 2022

Additive effect of erythropoietin use on exercise-induced endothelial activation and hypercoagulability in athletes

por Heuberger, Jules A. A. C., Posthuma, Jelle J., Ziagkos, Dimitrios, Rotmans, Joris I., Daniels, Johannes M. A., Gal, Pim, Stuurman, Frederik E., Spronk, Henri M. H., Ten Cate, Hugo, Burggraaf, Jacobus, Moerland, Matthijs, Cohen, Adam F.
Publicado 2020

EpoR stimulates rapid cycling and larger red cells during mouse and human erythropoiesis

por Hidalgo, Daniel, Bejder, Jacob, Pop, Ramona, Gellatly, Kyle, Hwang, Yung, Maxwell Scalf, S., Eastman, Anna E., Chen, Jane-Jane, Zhu, Lihua Julie, Heuberger, Jules A. A. C., Guo, Shangqin, Koury, Mark J., Nordsborg, Nikolai Baastrup, Socolovsky, Merav
Publicado 2021

Transcranial magnetic stimulation as a translational biomarker for AMPA receptor modulation

por O’Donnell, Patricio, Dijkstra, Francis M., Damar, Ugur, Quanhong, Lei, de Goede, Annika A., Xu, Lin, Pascual-Leone, Andres, Buhl, Derek L., Zuiker, Rob, Ruijs, Titia Q., Heuberger, Jules A. A. C., MacMullin, Paul, Lubell, Martin, Asgharnejad, Mahnaz, Murthy, Venkatesha, Rotenberg, Alexander, Jacobs, Gabriel E., Rosen, Laura
Publicado 2021

Safety, pharmacokinetics and target engagement of novel RIPK1 inhibitor SAR443060 (DNL747) for neurodegenerative disorders: Randomized, placebo‐controlled, double‐blind phase I/Ib...

por Vissers, Maurits F. J. M., Heuberger, Jules A. A. C., Groeneveld, Geert Jan, Oude Nijhuis, Jerome, De Deyn, Peter Paul, Hadi, Salah, Harris, Jeffrey, Tsai, Richard M., Cruz‐Herranz, Andres, Huang, Fen, Tong, Vincent, Erickson, Rebecca, Zhu, Yuda, Scearce‐Levie, Kimberly, Hsiao‐Nakamoto, Jennifer, Tang, Xinyan, Chang, Megan, Fox, Brian M., Estrada, Anthony A., Pomponio, Robert J., Alonso‐Alonso, Miguel, Zilberstein, Moshe, Atassi, Nazem, Troyer, Matthew D., Ho, Carole
Publicado 2022