Transcription start site signal profiling improves transposable element RNA expression analysis at locus-level

por Savytska, Natalia, Heutink, Peter, Bansal, Vikas
Publicado 2022

High Content Screening in Neurodegenerative Diseases

por Jain, Shushant, van Kesteren, Ronald E., Heutink, Peter
Publicado 2012

DGEclust: differential expression analysis of clustered count data

por Vavoulis, Dimitrios V, Francescatto, Margherita, Heutink, Peter, Gough, Julian
Publicado 2015

Epigenetic Age Acceleration in Frontotemporal Lobar Degeneration: A Comprehensive Analysis in the Blood and Brain

por Murthy, Megha, Rizzu, Patrizia, Heutink, Peter, Mill, Jonathan, Lashley, Tammaryn, Bettencourt, Conceição
Publicado 2023

Genome-Wide Prediction of Functional Gene-Gene Interactions Inferred from Patterns of Genetic Differentiation in Mice and Men

por Bochdanovits, Zoltán, Sondervan, David, Perillous, Sophie, van Beijsterveldt, Toos, Boomsma, Dorret, Heutink, Peter
Publicado 2008

Exploring the functional role of the CHRM2 gene in human cognition: results from a dense genotyping and brain expression study

por Gosso, Florencia M, de Geus, Eco JC, Polderman, Tinca JC, Boomsma, Dorret I, Posthuma, Danielle, Heutink, Peter
Publicado 2007

Comprehensive mRNA Expression Profiling Distinguishes Tauopathies and Identifies Shared Molecular Pathways

por Bronner, Iraad F., Bochdanovits, Zoltán, Rizzu, Patrizia, Kamphorst, Wouter, Ravid, Rivka, van Swieten, John C., Heutink, Peter
Publicado 2009

Variation at GRN 3′-UTR rs5848 Is Not Associated with a Risk of Frontotemporal Lobar Degeneration in Dutch Population

por Simón-Sánchez, Javier, Seelaar, Harro, Bochdanovits, Zoltán, Deeg, Dorly J. H., van Swieten, John C., Heutink, Peter
Publicado 2009

Deep learning–based cell composition analysis from tissue expression profiles

por Menden, Kevin, Marouf, Mohamed, Oller, Sergio, Dalmia, Anupriya, Magruder, Daniel Sumner, Kloiber, Karin, Heutink, Peter, Bonn, Stefan
Publicado 2020

Do consanguineous parents of a child affected by an autosomal recessive disease have more DNA identical-by-descent than similarly-related parents with healthy offspring? Design of...

por Teeuw, Marieke E, Henneman, Lidewij, Bochdanovits, Zoltan, Heutink, Peter, Kuik, Dirk J, Cornel, Martina C, ten Kate, Leo P
Publicado 2010

Profiling transcription initiation in human aged brain using deep-CAGE

por Francescatto, Margherita, Pardo, Luba, Rizzu, Patrizia, Vitezic, Morana, Simón-Sánchez, Javier, Takahashi, Hazuki, Daub, Carsten, Carninci, Piero, Heutink, Peter
Publicado 2011

Parkinsonian phenotype in Machado-Joseph disease (MJD/SCA3): a two-case report

por Bettencourt, Conceição, Santos, Cristina, Coutinho, Paula, Rizzu, Patrizia, Vasconcelos, João, Kay, Teresa, Cymbron, Teresa, Raposo, Mafalda, Heutink, Peter, Lima, Manuela
Publicado 2011

Integrated, automated maintenance, expansion and differentiation of 2D and 3D patient-derived cellular models for high throughput drug screening

por Boussaad, Ibrahim, Cruciani, Gérald, Bolognin, Silvia, Antony, Paul, Dording, Claire M., Kwon, Yong-Jun, Heutink, Peter, Fava, Eugenio, Schwamborn, Jens C., Krüger, Rejko
Publicado 2021

iPS Cell-Based Model for MAPT Haplotype as a Risk Factor for Human Tauopathies Identifies No Major Differences in TAU Expression

por Strauß, Tabea, Marvian-Tayaranian, Amir, Sadikoglou, Eldem, Dhingra, Ashutosh, Wegner, Florian, Trümbach, Dietrich, Wurst, Wolfgang, Heutink, Peter, Schwarz, Sigrid C., Höglinger, Günter U.
Publicado 2021

Brain DNA methylomic analysis of frontotemporal lobar degeneration reveals OTUD4 in shared dysregulated signatures across pathological subtypes

por Fodder, Katherine, Murthy, Megha, Rizzu, Patrizia, Toomey, Christina E., Hasan, Rahat, Humphrey, Jack, Raj, Towfique, Lunnon, Katie, Mill, Jonathan, Heutink, Peter, Lashley, Tammaryn, Bettencourt, Conceição
Publicado 2023

Evidence for Immune Response, Axonal Dysfunction and Reduced Endocytosis in the Substantia Nigra in Early Stage Parkinson’s Disease

por Dijkstra, Anke A., Ingrassia, Angela, de Menezes, Renee X., van Kesteren, Ronald E., Rozemuller, Annemieke J. M., Heutink, Peter, van de Berg, Wilma D. J.
Publicado 2015

PLA2G6 Mutations Related to Distinct Phenotypes: A New Case with Early-onset Parkinsonism

por Giri, Anamika, Guven, Gamze, Hanagasi, Hasmet, Hauser, Ann-Kathrin, Erginul-Unaltuna, Nihan, Bilgic, Basar, Gurvit, Hakan, Heutink, Peter, Gasser, Thomas, Lohmann, Ebba, Simón-Sánchez, Javier
Publicado 2016

Trehalose Improves Human Fibroblast Deficits in a New CHIP-Mutation Related Ataxia

por Casarejos, Maria Jose, Perucho, Juan, López-Sendón, Jose Luis, García de Yébenes, Justo, Bettencourt, Conceição, Gómez, Ana, Ruiz, Carolina, Heutink, Peter, Rizzu, Patrizia, Mena, Maria Angeles
Publicado 2014

FADS2 Genetic Variance in Combination with Fatty Acid Intake Might Alter Composition of the Fatty Acids in Brain

por Rizzi, Thais S., van der Sluis, Sophie, Derom, Catherine, Thiery, Evert, van Kesteren, Ronald E., Jacobs, Nele, Van Gestel, Sofie, Vlietinck, Robert, Verhage, Matthijs, Heutink, Peter, Posthuma, Danielle
Publicado 2013

C9orf72 is differentially expressed in the central nervous system and myeloid cells and consistently reduced in C9orf72, MAPT and GRN mutation carriers

por Rizzu, Patrizia, Blauwendraat, Cornelis, Heetveld, Sasja, Lynes, Emily M., Castillo-Lizardo, Melissa, Dhingra, Ashutosh, Pyz, Elwira, Hobert, Markus, Synofzik, Matthis, Simón-Sánchez, Javier, Francescatto, Margherita, Heutink, Peter
Publicado 2016