A statistical framework to evaluate virtual screening

por Zhao, Wei, Hevener, Kirk E, White, Stephen W, Lee, Richard E, Boyett, James M
Publicado 2009

Recent developments in topoisomerase-targeted cancer chemotherapy

por Hevener, KirkE., Verstak, Tatsiana A., Lutat, Katie E., Riggsbee, Daniel L., Mooney, Jeremiah W.
Publicado 2018

The Vacuolar Ca(2+) ATPase Pump Pmc1p Is Required for Candida albicans Pathogenesis

por Luna-Tapia, Arturo, DeJarnette, Christian, Sansevere, Emily, Reitler, Parker, Butts, Arielle, Hevener, Kirk E., Palmer, Glen E.
Publicado 2019

In vivo evaluation of Clostridioides difficile enoyl-ACP reductase II (FabK) Inhibition by phenylimidazole unveils a promising narrow-spectrum antimicrobial strategy

por Dureja, Chetna, Rutherford, Jacob T., Pavel, Fahad B. A., Norseeda, Krissada, Prah, Isaac, Sun, Dianqing, Hevener, Kirk E., Hurdle, Julian G.
Publicado 2023

Synergistic Inhibitor Binding to the Papain‐Like Protease of Human SARS Coronavirus: Mechanistic and Inhibitor Design Implications

por Lee, Hyun, Cao, Shuyi, Hevener, Kirk E., Truong, Lena, Gatuz, Joseph L., Patel, Kavankumar, Ghosh, Arun K., Johnson, Michael E.
Publicado 2013

1233. Identification of Novel Inhibitors of Clostridioides difficile Enoyl-Reductase II (FabK) by High-Throughput Virtual and Experimental Screening

por Wahrmund, Rebecca D, Avad, Kristiana A, Reeve, Stephanie M, Jones, Jesse A, La, Thao, Lee, Richard E, Hevener, Kirk E
Publicado 2020

High-Throughput Screening (HTS) and Hit Validation to Identify Small Molecule Inhibitors with Activity against NS3/4A proteases from Multiple Hepatitis C Virus Genotypes

por Lee, Hyun, Zhu, Tian, Patel, Kavankumar, Zhang, Yan-Yan, Truong, Lena, Hevener, Kirk E., Gatuz, Joseph L., Subramanya, Gitanjali, Jeong, Hyun-Young, Uprichard, Susan L., Johnson, Michael E.
Publicado 2013

Pharmacophore Modeling, Synthesis, and Antibacterial Evaluation of Chalcones and Derivatives

por Zhang, Mingming, Prior, Allan M., Maddox, Marcus M., Shen, Wan-Jou, Hevener, Kirk E., Bruhn, David F., Lee, Robin B., Singh, Aman P., Reinicke, Justin, Simmons, Charles J., Hurdle, Julian G., Lee, Richard E., Sun, Dianqing
Publicado 2018

Decoding a cryptic mechanism of metronidazole resistance among globally disseminated fluoroquinolone-resistant Clostridioides difficile

por Olaitan, Abiola O., Dureja, Chetna, Youngblom, Madison A., Topf, Madeline A., Shen, Wan-Jou, Gonzales-Luna, Anne J., Deshpande, Aditi, Hevener, Kirk E., Freeman, Jane, Wilcox, Mark H., Palmer, Kelli L., Garey, Kevin W., Pepperell, Caitlin S., Hurdle, Julian G.
Publicado 2023