Helminth immunoregulation: The role of parasite secreted proteins in modulating host immunity

por Hewitson, James P., Grainger, John R., Maizels, Rick M.
Publicado 2009

Susceptibility and immunity to helminth parasites

por Maizels, Rick M, Hewitson, James P, Smith, Katherine A
Publicado 2012

The Secreted Triose Phosphate Isomerase of Brugia malayi Is Required to Sustain Microfilaria Production In Vivo

por Hewitson, James P., Rückerl, Dominik, Harcus, Yvonne, Murray, Janice, Webb, Lauren M., Babayan, Simon A., Allen, Judith E., Kurniawan, Agnes, Maizels, Rick M.
Publicado 2014

IL-4 directly signals tissue-resident macrophages to proliferate beyond homeostatic levels controlled by CSF-1

por Jenkins, Stephen J., Ruckerl, Dominik, Thomas, Graham D., Hewitson, James P., Duncan, Sheelagh, Brombacher, Frank, Maizels, Rick M., Hume, David A., Allen, Judith E.
Publicado 2013

Innate and adaptive type 2 immune cell responses in genetically controlled resistance to intestinal helminth infection

por Filbey, Kara J, Grainger, John R, Smith, Katherine A, Boon, Louis, van Rooijen, Nico, Harcus, Yvonne, Jenkins, Stephen, Hewitson, James P, Maizels, Rick M
Publicado 2014

Bone marrow remodeling supports hematopoiesis in response to immune thrombocytopenia progression in mice

por Herd, Oliver J., Rani, Gulab Fatima, Hewitson, James P., Hogg, Karen, Stone, Andrew P., Cooper, Nichola, Kent, David G., Genever, Paul G., Hitchcock, Ian S.
Publicado 2021

Malat1 Suppresses Immunity to Infection through Promoting Expression of Maf and IL-10 in Th Cells

por Hewitson, James P., West, Katie A., James, Kylie R., Rani, Gulab Fatima, Dey, Nidhi, Romano, Audrey, Brown, Najmeeyah, Teichmann, Sarah A., Kaye, Paul M., Lagos, Dimitris
Publicado 2020

Secretion of Protective Antigens by Tissue-Stage Nematode Larvae Revealed by Proteomic Analysis and Vaccination-Induced Sterile Immunity

por Hewitson, James P., Ivens, Al C., Harcus, Yvonne, Filbey, Kara J., McSorley, Henry J., Murray, Janice, Bridgett, Stephen, Ashford, David, Dowle, Adam A., Maizels, Rick M.
Publicado 2013

Novel O-linked methylated glycan antigens decorate secreted immunodominant glycoproteins from the intestinal nematode Heligmosomoides polygyrus

por Hewitson, James P., Nguyen, D. Linh, van Diepen, Angela, Smit, Cornelis H., Koeleman, Carolien A., McSorley, Henry J., Murray, Janice, Maizels, Rick M., Hokke, Cornelis H.
Publicado 2016

CD317-Positive Immune Stromal Cells in Human “Mesenchymal Stem Cell” Populations

por Kay, Alasdair G., Fox, James M., Hewitson, James P., Stone, Andrew P., Robertson, Sophie, James, Sally, Wang, Xiao-nong, Kapasa, Elizabeth, Yang, Xuebin B., Genever, Paul G.
Publicado 2022

Corrigendum: CD317-Positive Immune Stromal Cells in Human “Mesenchymal Stem Cell” Populations

por Kay, Alasdair G., Fox, James M., Hewitson, James P., Stone, Andrew P., Robertson, Sophie, James, Sally, Wang, Xiao-nong, Kapasa, Elizabeth, Yang, Xuebin B., Genever, Paul G.
Publicado 2022

Macrophage Migration Inhibitory Factor (MIF) Is Essential for Type 2 Effector Cell Immunity to an Intestinal Helminth Parasite

por Filbey, Kara J., Varyani, Fumi, Harcus, Yvonne, Hewitson, James P., Smyth, Danielle J., McSorley, Henry J., Ivens, Alasdair, Nylén, Susanne, Rottenberg, Martin, Löser, Stephan, Maizels, Rick M.
Publicado 2019

Macrophage origin limits functional plasticity in helminth-bacterial co-infection

por Rückerl, Dominik, Campbell, Sharon M., Duncan, Sheelagh, Sutherland, Tara E., Jenkins, Stephen J., Hewitson, James P., Barr, Tom A., Jackson-Jones, Lucy H., Maizels, Rick M., Allen, Judith E.
Publicado 2017

TGF-β mimic proteins form an extended gene family in the murine parasite Heligmosomoides polygyrus

por Smyth, Danielle J., Harcus, Yvonne, White, Madeleine P.J., Gregory, William F., Nahler, Janina, Stephens, Ian, Toke-Bjolgerud, Edward, Hewitson, James P., Ivens, Alasdair, McSorley, Henry J., Maizels, Rick M.
Publicado 2018

The adult murine heart has a sparse, phagocytically active macrophage population that expands through monocyte recruitment and adopts an ‘M2’ phenotype in response to Th2 immunolog...

por Mylonas, Katie J., Jenkins, Stephen J., Castellan, Raphael F.P., Ruckerl, Dominik, McGregor, Kieran, Phythian-Adams, Alexander T., Hewitson, James P., Campbell, Sharon M., MacDonald, Andrew S., Allen, Judith E., Gray, Gillian A.
Publicado 2015

S6K2-mediated regulation of TRBP as a determinant of miRNA expression in human primary lymphatic endothelial cells

por Warner, Matthew J., Bridge, Katherine S., Hewitson, James P., Hodgkinson, Michael R., Heyam, Alex, Massa, Bailey C., Haslam, Jessica C., Chatzifrangkeskou, Maria, Evans, Gareth J.O., Plevin, Michael J., Sharp, Tyson V., Lagos, Dimitris
Publicado 2016

MyD88 Signaling Inhibits Protective Immunity to the Gastrointestinal Helminth Parasite Heligmosomoides polygyrus

por Reynolds, Lisa A., Harcus, Yvonne, Smith, Katherine A., Webb, Lauren M., Hewitson, James P., Ross, Ewan A., Brown, Sheila, Uematsu, Satoshi, Akira, Shizuo, Gray, David, Gray, Mohini, MacDonald, Andrew S., Cunningham, Adam F., Maizels, Rick M.
Publicado 2014

Helminth secretions induce de novo T cell Foxp3 expression and regulatory function through the TGF-β pathway

por Grainger, John R., Smith, Katie A., Hewitson, James P., McSorley, Henry J., Harcus, Yvonne, Filbey, Kara J., Finney, Constance A.M., Greenwood, Edward J.D., Knox, David P., Wilson, Mark S., Belkaid, Yasmine, Rudensky, Alexander Y., Maizels, Rick M.
Publicado 2010

Concerted Activity of IgG1 Antibodies and IL-4/IL-25-Dependent Effector Cells Trap Helminth Larvae in the Tissues following Vaccination with Defined Secreted Antigens, Providing St...

por Hewitson, James P., Filbey, Kara J., Esser-von Bieren, Julia, Camberis, Mali, Schwartz, Christian, Murray, Janice, Reynolds, Lisa A., Blair, Natalie, Robertson, Elaine, Harcus, Yvonne, Boon, Louis, Huang, Stanley Ching-Cheng, Yang, Lihua, Tu, Yizheng, Miller, Mark J., Voehringer, David, Le Gros, Graham, Harris, Nicola, Maizels, Rick M.
Publicado 2015

A structurally distinct TGF-β mimic from an intestinal helminth parasite potently induces regulatory T cells

por Johnston, Chris J. C., Smyth, Danielle J., Kodali, Ravindra B., White, Madeleine P. J., Harcus, Yvonne, Filbey, Kara J., Hewitson, James P., Hinck, Cynthia S., Ivens, Alasdair, Kemter, Andrea M., Kildemoes, Anna O., Le Bihan, Thierry, Soares, Dinesh C., Anderton, Stephen M., Brenn, Thomas, Wigmore, Stephen J., Woodcock, Hannah V., Chambers, Rachel C., Hinck, Andrew P., McSorley, Henry J., Maizels, Rick M.
Publicado 2017