Stabilization of G protein-coupled receptors by point mutations

por Heydenreich, Franziska M., Vuckovic, Ziva, Matkovic, Milos, Veprintsev, Dmitry B.
Publicado 2015

High-throughput mutagenesis using a two-fragment PCR approach

por Heydenreich, Franziska M., Miljuš, Tamara, Jaussi, Rolf, Benoit, Roger, Milić, Dalibor, Veprintsev, Dmitry B.
Publicado 2017

AAscan, PCRdesign and MutantChecker: A Suite of Programs for Primer Design and Sequence Analysis for High-Throughput Scanning Mutagenesis

por Sun, Dawei, Ostermaier, Martin K., Heydenreich, Franziska M., Mayer, Daniel, Jaussi, Rolf, Standfuss, Joerg, Veprintsev, Dmitry B.
Publicado 2013

The pocketome of G-protein-coupled receptors reveals previously untargeted allosteric sites

por Hedderich, Janik B., Persechino, Margherita, Becker, Katharina, Heydenreich, Franziska M., Gutermuth, Torben, Bouvier, Michel, Bünemann, Moritz, Kolb, Peter
Publicado 2022

GPCR activation mechanisms across classes and macro/microscales

por Hauser, Alexander S., Kooistra, Albert J., Munk, Christian, Heydenreich, Franziska M., Veprintsev, Dmitry B., Bouvier, Michel, Babu, M. Madan, Gloriam, David E.
Publicado 2021

Functional solubilization of the β(2)-adrenoceptor using diisobutylene maleic acid

por Harwood, Clare.R., Sykes, David A., Hoare, Bradley L., Heydenreich, Franziska M., Uddin, Romez, Poyner, David R., Briddon, Stephen J., Veprintsev, D.B.
Publicado 2021

Membrane phosphoinositides regulate GPCR-β-arrestin complex assembly and dynamics

por Janetzko, John, Kise, Ryoji, Barsi-Rhyne, Benjamin, Siepe, Dirk H., Heydenreich, Franziska M., Kawakami, Kouki, Masureel, Matthieu, Maeda, Shoji, Garcia, K. Christopher, von Zastrow, Mark, Inoue, Asuka, Kobilka, Brian K.
Publicado 2022

Computationally designed GPCR quaternary structures bias signaling pathway activation

por Paradis, Justine S., Feng, Xiang, Murat, Brigitte, Jefferson, Robert E., Sokrat, Badr, Szpakowska, Martyna, Hogue, Mireille, Bergkamp, Nick D., Heydenreich, Franziska M., Smit, Martine J., Chevigné, Andy, Bouvier, Michel, Barth, Patrick
Publicado 2022

A new inhibitor of the β-arrestin/AP2 endocytic complex reveals interplay between GPCR internalization and signalling

por Beautrait, Alexandre, Paradis, Justine S., Zimmerman, Brandon, Giubilaro, Jenna, Nikolajev, Ljiljana, Armando, Sylvain, Kobayashi, Hiroyuki, Yamani, Lama, Namkung, Yoon, Heydenreich, Franziska M., Khoury, Etienne, Audet, Martin, Roux, Philippe P., Veprintsev, Dmitry B., Laporte, Stéphane A., Bouvier, Michel
Publicado 2017