Functional Screening of Parkinson’s Disease Susceptibility Genes to Identify Novel Modulators of α-Synuclein Neurotoxicity in Caenorhabditis elegans

por Vozdek, Roman, Pramstaller, Peter P., Hicks, Andrew A.
Publicado 2022

SLP-2: a potential new target for improving mitochondrial function in Parkinson's disease

por Zanon, Alessandra, Hicks, Andrew A., Pramstaller, Peter P., Pichler, Irene
Publicado 2017

Environmental and Genetic Variables Influencing Mitochondrial Health and Parkinson's Disease Penetrance

por Zanon, Alessandra, Pramstaller, Peter P., Hicks, Andrew A., Pichler, Irene
Publicado 2018

Update on the management of restless legs syndrome: existing and emerging treatment options

por Facheris, Maurizio F, Hicks, Andrew A, Pramstaller, Peter P, Pichler, Irene
Publicado 2010

The Impact of CRISPR/Cas9 Technology on Cardiac Research: From Disease Modelling to Therapeutic Approaches

por Motta, Benedetta M., Pramstaller, Peter P., Hicks, Andrew A., Rossini, Alessandra
Publicado 2017

A new hypothesis for Parkinson’s disease pathogenesis: GTPase-p38 MAPK signaling and autophagy as convergence points of etiology and genomics

por Obergasteiger, Julia, Frapporti, Giulia, Pramstaller, Peter P., Hicks, Andrew A., Volta, Mattia
Publicado 2018

A genome on shaky ground: exploring the impact of mitochondrial DNA integrity on Parkinson’s disease by highlighting the use of cybrid models

por Lang, Martin, Grünewald, Anne, Pramstaller, Peter P., Hicks, Andrew A., Pichler, Irene
Publicado 2022

Plasmid-normalized quantification of relative mitochondrial DNA copy number

por Fazzini, Federica, Schöpf, Bernd, Blatzer, Michael, Coassin, Stefan, Hicks, Andrew A., Kronenberg, Florian, Fendt, Liane
Publicado 2018

Fluorescent reporter of  Caenorhabditis elegans Parkin: Regulators of its abundance and role in autophagy-lysosomal dynamics

por Vozdek, Roman, Wang, Bingying, Li, Kathy H., Pramstaller, Peter P., Hicks, Andrew A., Ma, Dengke K.
Publicado 2023

Participant perspective on the recall-by-genotype research approach: a mixed-method embedded study with participants of the CHRIS study

por Biasiotto, Roberta, Kösters, Maria, Tschigg, Katharina, Pramstaller, Peter P., Brüggemann, Norbert, Borsche, Max, Klein, Christine, Hicks, Andrew A., Mascalzoni, Deborah
Publicado 2023

Identification of a set of endogenous reference genes for miRNA expression studies in Parkinson’s disease blood samples

por Serafin, Alice, Foco, Luisa, Blankenburg, Hagen, Picard, Anne, Zanigni, Stefano, Zanon, Alessandra, Pramstaller, Peter P, Hicks, Andrew A, Schwienbacher, Christine
Publicado 2014

Interaction of Alpha-Synuclein With Lipids: Mitochondrial Cardiolipin as a Critical Player in the Pathogenesis of Parkinson’s Disease

por Gilmozzi, Valentina, Gentile, Giovanna, Castelo Rueda, Maria Paulina, Hicks, Andrew A., Pramstaller, Peter P., Zanon, Alessandra, Lévesque, Martin, Pichler, Irene
Publicado 2020

Evaluation of the role of STAP1 in Familial Hypercholesterolemia

por Danyel, Magdalena, Ott, Claus-Eric, Grenkowitz, Thomas, Salewsky, Bastian, Hicks, Andrew A., Fuchsberger, Christian, Steinhagen-Thiessen, Elisabeth, Bobbert, Thomas, Kassner, Ursula, Demuth, Ilja
Publicado 2019

Induced Pluripotent Stem Cell (iPSC) Lines from a Family with Resistant Epileptic Encephalopathy Caused by Compound Heterozygous Mutations in SZT2 Gene

por Cattelani, Cecilia, Battistella, Ingrid, Di Leva, Francesca, Fioravanti, Giulia, Benedicenti, Francesco, Stanzial, Franco, Schwienbacher, Christine, Fanelli, Francesca, Pramstaller, Peter P., Hicks, Andrew A., Conti, Luciano, Corti, Corrado
Publicado 2022

Copy Number Variation across European Populations

por Chen, Wanting, Hayward, Caroline, Wright, Alan F., Hicks, Andrew A., Vitart, Veronique, Knott, Sara, Wild, Sarah H., Pramstaller, Peter P., Wilson, James F., Rudan, Igor, Porteous, David J.
Publicado 2011

The small GTPase Rit2 modulates LRRK2 kinase activity, is required for lysosomal function and protects against alpha-synuclein neuropathology

por Obergasteiger, Julia, Castonguay, Anne-Marie, Pizzi, Sara, Magnabosco, Stefano, Frapporti, Giulia, Lobbestael, Evy, Baekelandt, Veerle, Hicks, Andrew A., Pramstaller, Peter P., Gravel, Claude, Corti, Corrado, Lévesque, Martin, Volta, Mattia
Publicado 2023

Parkin Interacts with Apoptosis-Inducing Factor and Interferes with Its Translocation to the Nucleus in Neuronal Cells

por Guida, Marianna, Zanon, Alessandra, Montibeller, Luigi, Lavdas, Alexandros A., Ladurner, Judith, Pischedda, Francesca, Rakovic, Aleksandar, Domingues, Francisco S., Piccoli, Giovanni, Klein, Christine, Pramstaller, Peter P., Hicks, Andrew A., Pichler, Irene
Publicado 2019

Frequency of Heterozygous Parkin (PRKN) Variants and Penetrance of Parkinson's Disease Risk Markers in the Population-Based CHRIS Cohort

por Castelo Rueda, Maria Paulina, Raftopoulou, Athina, Gögele, Martin, Borsche, Max, Emmert, David, Fuchsberger, Christian, Hantikainen, Essi M., Vukovic, Vladimir, Klein, Christine, Pramstaller, Peter P., Pichler, Irene, Hicks, Andrew A.
Publicado 2021

Increased Levels of the Parkinson’s Disease-Associated Gene ITPKB Correlate with Higher Expression Levels of α-Synuclein, Independent of Mutation Status

por Di Leva, Francesca, Filosi, Michele, Oyston, Lisa, Silvestri, Erica, Picard, Anne, Lavdas, Alexandros A., Lobbestael, Evy, Baekelandt, Veerle, Neely, G. Gregory, Pramstaller, Peter P., Hicks, Andrew A., Corti, Corrado
Publicado 2023

Balancing scientific interests and the rights of participants in designing a recall by genotype study

por Mascalzoni, Deborah, Biasiotto, Roberta, Borsche, Max, Brüggemann, Norbert, De Grandi, Alessandro, Goegele, Martin, Frygner-Holm, Sara, Klein, Christine, Kösters, Maria, Staunton, Ciara, Pramstaller, Peter P., Krawczak, Michael, Hicks, Andrew A.
Publicado 2021