Human CTP synthase filament structure reveals the active enzyme conformation

por Lynch, Eric M., Hicks, Derrick R., Shepherd, Matthew, Endrizzi, James A., Maker, Allison, Hansen, Jesse M., Barry, Rachael M., Gitai, Zemer, Baldwin, Enoch P., Kollman, Justin M.
Publicado 2017

De novo design of protein homodimers containing tunable symmetric protein pockets

por Hicks, Derrick R., Kennedy, Madison A., Thompson, Kirsten A., DeWitt, Michelle, Coventry, Brian, Kang, Alex, Bera, Asim K., Brunette, T. J., Sankaran, Banumathi, Stoddard, Barry, Baker, David
Publicado 2022

Hallucination of closed repeat proteins containing central pockets

por An, Linna, Hicks, Derrick R., Zorine, Dmitri, Dauparas, Justas, Wicky, Basile I. M., Milles, Lukas F., Courbet, Alexis, Bera, Asim K., Nguyen, Hannah, Kang, Alex, Carter, Lauren, Baker, David
Publicado 2023

Design of Diverse Asymmetric Pockets in De Novo Homo-oligomeric Proteins

por Gerben, Stacey R, Borst, Andrew J, Hicks, Derrick R, Moczygemba, Isabelle, Feldman, David, Coventry, Brian, Yang, Wei, Bera, Asim K., Miranda, Marcos, Kang, Alex, Nguyen, Hannah, Baker, David
Publicado 2023

De novo design of modular peptide-binding proteins by superhelical matching

por Wu, Kejia, Bai, Hua, Chang, Ya-Ting, Redler, Rachel, McNally, Kerrie E., Sheffler, William, Brunette, T. J., Hicks, Derrick R., Morgan, Tomos E., Stevens, Tim J., Broerman, Adam, Goreshnik, Inna, DeWitt, Michelle, Chow, Cameron M., Shen, Yihang, Stewart, Lance, Derivery, Emmanuel, Silva, Daniel Adriano, Bhabha, Gira, Ekiert, Damian C., Baker, David
Publicado 2023

Scaffolding protein functional sites using deep learning

por Wang, Jue, Lisanza, Sidney, Juergens, David, Tischer, Doug, Watson, Joseph L., Castro, Karla M., Ragotte, Robert, Saragovi, Amijai, Milles, Lukas F., Baek, Minkyung, Anishchenko, Ivan, Yang, Wei, Hicks, Derrick R., Expòsit, Marc, Schlichthaerle, Thomas, Chun, Jung-Ho, Dauparas, Justas, Bennett, Nathaniel, Wicky, Basile I. M., Muenks, Andrew, DiMaio, Frank, Correia, Bruno, Ovchinnikov, Sergey, Baker, David
Publicado 2022

Modulation of FGF pathway signaling and vascular differentiation using designed oligomeric assemblies

por Edman, Natasha I, Redler, Rachel L, Phal, Ashish, Schlichthaerle, Thomas, Srivatsan, Sanjay R, Etemadi, Ali, An, Seong J, Favor, Andrew, Ehnes, Devon, Li, Zhe, Praetorius, Florian, Gordon, Max, Yang, Wei, Coventry, Brian, Hicks, Derrick R., Cao, Longxing, Bethel, Neville, Heine, Piper, Murray, Analisa, Gerben, Stacey, Carter, Lauren, Miranda, Marcos, Negahdari, Babak, Lee, Sangwon, Trapnell, Cole, Stewart, Lance, Ekiert, Damian C., Schlessinger, Joseph, Shendure, Jay, Bhabha, Gira, Ruohola-Baker, Hannele, Baker, David
Publicado 2023