Hypoxia inducible factors regulate the transcription of the sprouty2 gene and expression of the sprouty2 protein

por Gao, Xianlong, Hicks, Kristin C., Neumann, Paul, Patel, Tarun B.
Publicado 2017

Mechanisms involved in IL-15 superagonist enhancement of anti-PD-L1 therapy

por Knudson, Karin M., Hicks, Kristin C., Alter, Sarah, Schlom, Jeffrey, Gameiro, Sofia R.
Publicado 2019

Functional and mechanistic advantage of the use of a bifunctional anti-PD-L1/IL-15 superagonist

por Knudson, Karin M, Hicks, Kristin C, Ozawa, Yohei, Schlom, Jeffrey, Gameiro, Sofia R
Publicado 2020

M7824, a novel bifunctional anti-PD-L1/TGFβ Trap fusion protein, promotes anti-tumor efficacy as monotherapy and in combination with vaccine

por Knudson, Karin M., Hicks, Kristin C., Luo, Xiaoling, Chen, Jin-Qiu, Schlom, Jeffrey, Gameiro, Sofia R.
Publicado 2018

Analysis of the tumor microenvironment and anti-tumor efficacy of subcutaneous vs systemic delivery of the bifunctional agent bintrafusp alfa

por Ozawa, Yohei, Hicks, Kristin C., Minnar, Christine M., Knudson, Karin M., Schlom, Jeffrey, Gameiro, Sofia R.
Publicado 2021

Tumor-targeted interleukin-12 synergizes with entinostat to overcome PD-1/PD-L1 blockade-resistant tumors harboring MHC-I and APM deficiencies

por Minnar, Christine M, Chariou, Paul L, Horn, Lucas A, Hicks, Kristin C, Palena, Claudia, Schlom, Jeffrey, Gameiro, Sofia R
Publicado 2022

Tumour-targeted interleukin-12 and entinostat combination therapy improves cancer survival by reprogramming the tumour immune cell landscape

por Hicks, Kristin C., Chariou, Paul L., Ozawa, Yohei, Minnar, Christine M., Knudson, Karin M., Meyer, Thomas J., Bian, Jing, Cam, Margaret, Schlom, Jeffrey, Gameiro, Sofia R.
Publicado 2021

Epigenetic priming of both tumor and NK cells augments antibody-dependent cellular cytotoxicity elicited by the anti-PD-L1 antibody avelumab against multiple carcinoma cell types

por Hicks, Kristin C., Fantini, Massimo, Donahue, Renee N., Schwab, Angie, Knudson, Karin M., Tritsch, Sarah R., Jochems, Caroline, Clavijo, Paul E., Allen, Clint T., Hodge, James W., Tsang, Kwong Y., Schlom, Jeffrey, Gameiro, Sofia R.
Publicado 2018

Improving the Odds in Advanced Breast Cancer With Combination Immunotherapy: Stepwise Addition of Vaccine, Immune Checkpoint Inhibitor, Chemotherapy, and HDAC Inhibitor in Advanced...

por Gatti-Mays, Margaret E., Gameiro, Sofia R., Ozawa, Yohei, Knudson, Karin M., Hicks, Kristin C., Palena, Claudia, Cordes, Lisa M., Steinberg, Seth M., Francis, Deneise, Karzai, Fatima, Lipkowitz, Stanley, Donahue, Renee N., Jochems, Caroline, Schlom, Jeffrey, Gulley, James L.
Publicado 2021