Sildenafil, a Type-5 Phosphodiesterase Inhibitor, Fails to Reverse Myeloid-Derived Suppressor Cell-Mediated T Cell Suppression in Cells Isolated From Tuberculosis Patients

por Leukes, Vinzeigh N., Malherbe, Stephanus T., Hiemstra, Andriette, Kotze, Leigh A., Roos, Kelly, Keyser, Alana, De Swardt, Dalene, Gutschmidt, Andrea, Walzl, Gerhard, du Plessis, Nelita
Publicado 2022

Establishment of a Patient-Derived, Magnetic Levitation-Based, Three-Dimensional Spheroid Granuloma Model for Human Tuberculosis

por Kotze, Leigh A., Beltran, Caroline G. G., Lang, Dirk, Loxton, Andre G., Cooper, Susan, Meiring, Maynard, Koegelenberg, Coenraad F. N., Allwood, Brian W., Malherbe, Stephanus T., Hiemstra, Andriette M., Glanzmann, Brigitte, Kinnear, Craig, Walzl, Gerhard, du Plessis, Nelita
Publicado 2021

Higher SARS-CoV-2 seroprevalence in workers with lower socioeconomic status in Cape Town, South Africa

por Shaw, Jane Alexandra, Meiring, Maynard, Cummins, Tracy, Chegou, Novel N., Claassen, Conita, Du Plessis, Nelita, Flinn, Marika, Hiemstra, Andriette, Kleynhans, Léanie, Leukes, Vinzeigh, Loxton, Andre G., MacDonald, Candice, Mtala, Nosipho, Reuter, Helmuth, Simon, Donald, Stanley, Kim, Tromp, Gerard, Preiser, Wolfgang, Malherbe, Stephanus T., Walzl, Gerhard
Publicado 2021

Optimising the yield from bronchoalveolar lavage on human participants in infectious disease immunology research

por Shaw, Jane Alexandra, Meiring, Maynard, Allies, Devon, Cruywagen, Lauren, Fisher, Tarryn-Lee, Kasavan, Kesheera, Roos, Kelly, Botha, Stefan Marc, MacDonald, Candice, Hiemstra, Andriëtte M., Simon, Donald, van Rensburg, Ilana, Flinn, Marika, Shabangu, Ayanda, Kuivaniemi, Helena, Tromp, Gerard, Malherbe, Stephanus T., Walzl, Gerhard, du Plessis, Nelita
Publicado 2023

GPR183 Regulates Interferons, Autophagy, and Bacterial Growth During Mycobacterium tuberculosis Infection and Is Associated With TB Disease Severity

por Bartlett, Stacey, Gemiarto, Adrian Tandhyka, Ngo, Minh Dao, Sajiir, Haressh, Hailu, Semira, Sinha, Roma, Foo, Cheng Xiang, Kleynhans, Léanie, Tshivhula, Happy, Webber, Tariq, Bielefeldt-Ohmann, Helle, West, Nicholas P., Hiemstra, Andriette M., MacDonald, Candice E., Christensen, Liv von Voss, Schlesinger, Larry S., Walzl, Gerhard, Rosenkilde, Mette Marie, Mandrup-Poulsen, Thomas, Ronacher, Katharina
Publicado 2020

Biomarker-guided tuberculosis preventive therapy (CORTIS): a randomised controlled trial

por Scriba, Thomas J, Fiore-Gartland, Andrew, Penn-Nicholson, Adam, Mulenga, Humphrey, Kimbung Mbandi, Stanley, Borate, Bhavesh, Mendelsohn, Simon C, Hadley, Katie, Hikuam, Chris, Kaskar, Masooda, Musvosvi, Munyaradzi, Bilek, Nicole, Self, Steven, Sumner, Tom, White, Richard G, Erasmus, Mzwandile, Jaxa, Lungisa, Raphela, Rodney, Innes, Craig, Brumskine, William, Hiemstra, Andriëtte, Malherbe, Stephanus T, Hassan-Moosa, Razia, Tameris, Michèle, Walzl, Gerhard, Naidoo, Kogieleum, Churchyard, Gavin, Hatherill, Mark
Publicado 2021

Validation of a host blood transcriptomic biomarker for pulmonary tuberculosis in people living with HIV: a prospective diagnostic and prognostic accuracy study

por Mendelsohn, Simon C, Fiore-Gartland, Andrew, Penn-Nicholson, Adam, Mulenga, Humphrey, Mbandi, Stanley Kimbung, Borate, Bhavesh, Hadley, Katie, Hikuam, Chris, Musvosvi, Munyaradzi, Bilek, Nicole, Erasmus, Mzwandile, Jaxa, Lungisa, Raphela, Rodney, Nombida, Onke, Kaskar, Masooda, Sumner, Tom, White, Richard G, Innes, Craig, Brumskine, William, Hiemstra, Andriëtte, Malherbe, Stephanus T, Hassan-Moosa, Razia, Tameris, Michèle, Walzl, Gerhard, Naidoo, Kogieleum, Churchyard, Gavin, Scriba, Thomas J, Hatherill, Mark
Publicado 2021

Longitudinal Dynamics of a Blood Transcriptomic Signature of Tuberculosis

por Mulenga, Humphrey, Musvosvi, Munyaradzi, Mendelsohn, Simon C., Penn-Nicholson, Adam, Kimbung Mbandi, Stanley, Fiore-Gartland, Andrew, Tameris, Michèle, Mabwe, Simbarashe, Africa, Hadn, Bilek, Nicole, Kafaar, Fazlin, Khader, Shabaana A., Carstens, Balie, Hadley, Katie, Hikuam, Chris, Erasmus, Mzwandile, Jaxa, Lungisa, Raphela, Rodney, Nombida, Onke, Kaskar, Masooda, Nicol, Mark P., Mbhele, Slindile, Van Heerden, Judi, Innes, Craig, Brumskine, William, Hiemstra, Andriëtte, Malherbe, Stephanus T., Hassan-Moosa, Razia, Walzl, Gerhard, Naidoo, Kogieleum, Churchyard, Gavin, Hatherill, Mark, Scriba, Thomas J.
Publicado 2021