Ultrahigh resolution MS(1)/MS(2)-based reconstruction of metabolic networks in mammalian cells reveals changes for selenite and arsenite action

por Fan, Teresa W.-M., Sun, Qiushi, Higashi, Richard M.
Publicado 2022

Metabolic reprogramming in tumors: Contributions of the tumor microenvironment

por Lane, Andrew N., Higashi, Richard M., Fan, Teresa W-M.
Publicado 2019

Resolving Metabolic Heterogeneity in Experimental Models of the Tumor Microenvironment from a Stable Isotope Resolved Metabolomics Perspective

por Fan, Teresa W. -M., Higashi, Richard M., Chernayavskaya, Yelena, Lane, Andrew N.
Publicado 2020

6-Phosphogluconate dehydrogenase (6PGD), a key checkpoint in reprogramming of regulatory T cells metabolism and function

por Daneshmandi, Saeed, Cassel, Teresa, Higashi, Richard M, Fan, Teresa W-M, Seth, Pankaj
Publicado 2021

A novel deconvolution method for modeling UDP-N-acetyl-D-glucosamine biosynthetic pathways based on (13)C mass isotopologue profiles under non-steady-state conditions

por Moseley, Hunter NB, Lane, Andrew N, Belshoff, Alex C, Higashi, Richard M, Fan, Teresa WM
Publicado 2011

A novel deconvolution method for modeling UDP-N-acetyl-D-glucosamine biosynthetic pathways based on (13)C mass isotopologue profiles under non-steady-state conditions

por Moseley, Hunter NB, Lane, Andrew N, Belshoff, Alex C, Higashi, Richard M, Fan, Teresa WM
Publicado 2012

Rhabdomyosarcoma cells show an energy producing anabolic metabolic phenotype compared with primary myocytes

por Fan, Teresa WM, Kucia, Magda, Jankowski, Kacper, Higashi, Richard M, Ratajczak, Janina, Ratajczak, Marius Z, Lane, Andrew N
Publicado 2008

Altered regulation of metabolic pathways in human lung cancer discerned by (13)C stable isotope-resolved metabolomics (SIRM)

por Fan, Teresa WM, Lane, Andrew N, Higashi, Richard M, Farag, Mohamed A, Gao, Hong, Bousamra, Michael, Miller, Donald M
Publicado 2009

Differential Abundance Analysis with Bayes Shrinkage Estimation of Variance (DASEV) for Zero-Inflated Proteomic and Metabolomic Data

por Huang, Zhengyan, Lane, Andrew N., Fan, Teresa W-M., Higashi, Richard M., Weiss, Heidi L., Yin, Xiangrong, Wang, Chi
Publicado 2020

Antagonistic effects of MYC and hypoxia in channeling glucose and glutamine into de novo nucleotide biosynthesis

por Fan, Teresa, Le, Anne, Stine, Zachary, Yang, Ye, Zeller, Karen, Zhou, Weiqiang, Ji, Hongkai, Higashi, Richard, Dang, Chi, Lane, Andrew
Publicado 2014

NMR Methods for Determining Lipid Turnover via Stable Isotope Resolved Metabolomics

por Lin, Penghui, Dai, Li, Crooks, Daniel R., Neckers, Leonard M., Higashi, Richard M., Fan, Teresa W-M., Lane, Andrew N.
Publicado 2021

Blockade of 6-phosphogluconate dehydrogenase generates CD8(+) effector T cells with enhanced anti-tumor function

por Daneshmandi, Saeed, Cassel, Teresa, Lin, Penghui, Higashi, Richard M., Wulf, Gerburg M., Boussiotis, Vassiliki A., Fan, Teresa W.-M., Seth, Pankaj
Publicado 2021

New methods to identify high peak density artifacts in Fourier transform mass spectra and to mitigate their effects on high-throughput metabolomic data analysis

por Mitchell, Joshua M., Flight, Robert M., Wang, Qing Jun, Higashi, Richard M., Fan, Teresa W.-M., Lane, Andrew N., Moseley, Hunter N. B.
Publicado 2018

A Micro-Scale Analytical Method for Determining Glycogen Turnover by NMR and FTMS

por Scott, Timothy L., Zhu, Juan, Cassel, Teresa A., Vicente-Muñoz, Sara, Lin, Penghui, Higashi, Richard M., Lane, Andrew N., Fan, Teresa W.-M.
Publicado 2022

Knockdown of Malic Enzyme 2 Suppresses Lung Tumor Growth, Induces Differentiation and Impacts PI3K/AKT Signaling

por Ren, Jian-Guo, Seth, Pankaj, Clish, Clary B., Lorkiewicz, Pawel K., Higashi, Richard M., Lane, Andrew N., Fan, Teresa W.-M., Sukhatme, Vikas P.
Publicado 2014

Distinctly perturbed metabolic networks underlie differential tumor tissue damages induced by immune modulator β-glucan in a two-case ex vivo non-small-cell lung cancer study

por Fan, Teresa W.-M., Warmoes, Marc O., Sun, Qiushi, Song, Huan, Turchan-Cholewo, Jadwiga, Martin, Jeremiah T., Mahan, Angela, Higashi, Richard M., Lane, Andrew N.
Publicado 2016

Metabolomics Workbench: An international repository for metabolomics data and metadata, metabolite standards, protocols, tutorials and training, and analysis tools

por Sud, Manish, Fahy, Eoin, Cotter, Dawn, Azam, Kenan, Vadivelu, Ilango, Burant, Charles, Edison, Arthur, Fiehn, Oliver, Higashi, Richard, Nair, K. Sreekumaran, Sumner, Susan, Subramaniam, Shankar
Publicado 2016

Differential Inhibition of Anaplerotic Pyruvate Carboxylation and Glutaminolysis-Fueled Anabolism Underlies Distinct Toxicity of Selenium Agents in Human Lung Cancer

por Fan, Teresa W.-M., Winnike, Jason, Al-Attar, Ahmad, Belshoff, Alexander C., Lorkiewicz, Pawel K., Tan, Jin Lian, Wu, Min, Higashi, Richard M., Lane, Andrew N.
Publicado 2023

Cyclin D1 extensively reprograms metabolism to support biosynthetic pathways in hepatocytes

por Wu, Heng, Kren, Betsy T., Lane, Andrew N., Cassel, Teresa A., Higashi, Richard M., Fan, Teresa W.M., Scaria, George S., Shekels, Laurie L., Klein, Mark A., Albrecht, Jeffrey H.
Publicado 2023

Noninvasive liquid diet delivery of stable isotopes into mouse models for deep metabolic network tracing

por Sun, Ramon C., Fan, Teresa W.-M., Deng, Pan, Higashi, Richard M., Lane, Andrew N., Le, Anh-Thu, Scott, Timothy L., Sun, Qiushi, Warmoes, Marc O., Yang, Ye
Publicado 2017