The Roles of SPOP in DNA Damage Response and DNA Replication

por Maekawa, Masashi, Higashiyama, Shigeki
Publicado 2020

Proteolytic release of the carboxy-terminal fragment of proHB-EGF causes nuclear export of PLZF

por Nanba, Daisuke, Mammoto, Akiko, Hashimoto, Koji, Higashiyama, Shigeki
Publicado 2003

Efficient expansion of human keratinocyte stem/progenitor cells carrying a transgene with lentiviral vector

por Nanba, Daisuke, Matsushita, Natsuki, Toki, Fujio, Higashiyama, Shigeki
Publicado 2013

Semaphorin 3F and Netrin-1: The Novel Function as a Regulator of Tumor Microenvironment

por Nakayama, Hironao, Kusumoto, Chiaki, Nakahara, Masako, Fujiwara, Akira, Higashiyama, Shigeki
Publicado 2018

Notch increases the shedding of HB-EGF by ADAM12 to potentiate invadopodia formation in hypoxia

por Díaz, Begoña, Yuen, Angela, Iizuka, Shinji, Higashiyama, Shigeki, Courtneidge, Sara A.
Publicado 2013

Actin filament dynamics impacts keratinocyte stem cell maintenance

por Nanba, Daisuke, Toki, Fujio, Matsushita, Natsuki, Matsushita, Sachi, Higashiyama, Shigeki, Barrandon, Yann
Publicado 2013

The cytoplasmic tail of heparin-binding EGF-like growth factor regulates bidirectional intracellular trafficking between the plasma membrane and ER

por Hieda, Miki, Koizumi, Michiko, Higashi, Chiduru, Tachibana, Taro, Taguchi, Tomohiko, Higashiyama, Shigeki
Publicado 2012

Heparin-binding EGF-like growth factor enhances the activity of invasion and metastasis in thyroid cancer cells

por OTA, ICHIRO, HIGASHIYAMA, SHIGEKI, MASUI, TAKASHI, YANE, KATSUNARI, HOSOI, HIROSHI, MATSUURA, NARIAKI
Publicado 2013

The molecular mechanism of phytosphingosine binding to FFAR4/GPR120 differs from that of other fatty acids

por Nagasawa, Tomotaka, Horitani, Masaki, Kawaguchi, Shin‐ichi, Higashiyama, Shigeki, Hama, Yoichiro, Mitsutake, Susumu
Publicado 2021

Human TMEM2 is not a catalytic hyaluronidase, but a regulator of hyaluronan metabolism via HYBID (KIAA1199/CEMIP) and HAS2 expression

por Sato, Shinya, Miyazaki, Megumi, Fukuda, Shinji, Mizutani, Yukiko, Mizukami, Yoichi, Higashiyama, Shigeki, Inoue, Shintaro
Publicado 2023

Effects of promyelocytic leukemia zinc finger protein on the proliferation of cultured human corneal endothelial cells

por Joko, Takeshi, Nanba, Daisuke, Shiba, Fumio, Miyata, Kazunori, Shiraishi, Atsushi, Ohashi, Yuichi, Higashiyama, Shigeki
Publicado 2007

A Disintegrin and Metalloenzyme (ADAM) 17 Activation Is Regulated by α5β1 Integrin in Kidney Mesangial Cells

por Gooz, Pal, Dang, Yujing, Higashiyama, Shigeki, Twal, Waleed O., Haycraft, Courtney J., Gooz, Monika
Publicado 2012

Cisplatin resistance by induction of aldo-keto reductase family 1 member C2 in human bladder cancer cells

por SHIRATO, AKITOMI, KIKUGAWA, TADAHIKO, MIURA, NORIYOSHI, TANJI, NOZOMU, TAKEMORI, NOBUAKI, HIGASHIYAMA, SHIGEKI, YOKOYAMA, MASAYOSHI
Publicado 2014

Glutamate-dependent ectodomain shedding of neuregulin-1 type II precursors in rat forebrain neurons

por Iwakura, Yuriko, Wang, Ran, Inamura, Naoko, Araki, Kazuaki, Higashiyama, Shigeki, Takei, Nobuyuki, Nawa, Hiroyuki
Publicado 2017

Heparin‐binding Epidermal Growth Factor‐like Growth Factor: p91 Activation, Induction of Plasminogen Activator/Plasminogen Activator Inhibitor, and Tubular Morphogenesis in Human M...

por Ushiro, Shin, Ono, Mayumi, Izumi, Hiroto, Kohno, Kimitoshi, Taniguchi, Naoyuki, Higashiyama, Shigeki, Kuwano, Michihiko
Publicado 1996

Cell surface annexins regulate ADAM-mediated ectodomain shedding of proamphiregulin

por Nakayama, Hironao, Fukuda, Shinji, Inoue, Hirofumi, Nishida-Fukuda, Hisayo, Shirakata, Yuji, Hashimoto, Koji, Higashiyama, Shigeki
Publicado 2012

Reversible interconversion and maintenance of mammary epithelial cell characteristics by the ligand-regulated EGFR system

por Fukuda, Shinji, Nishida-Fukuda, Hisayo, Nanba, Daisuke, Nakashiro, Koh-ichi, Nakayama, Hironao, Kubota, Hiroyuki, Higashiyama, Shigeki
Publicado 2016

SPOP is essential for DNA–protein cross-link repair in prostate cancer cells: SPOP-dependent removal of topoisomerase 2A from the topoisomerase 2A-DNA cleavage complex

por Watanabe, Ryuta, Maekawa, Masashi, Hieda, Miki, Taguchi, Tomohiko, Miura, Noriyoshi, Kikugawa, Tadahiko, Saika, Takashi, Higashiyama, Shigeki
Publicado 2020

Inner Nuclear Membrane Protein, SUN1, is Required for Cytoskeletal Force Generation and Focal Adhesion Maturation

por Ueda, Nanami, Maekawa, Masashi, Matsui, Tsubasa S., Deguchi, Shinji, Takata, Tomoyo, Katahira, Jun, Higashiyama, Shigeki, Hieda, Miki
Publicado 2022

PSMA‐positive membranes secreted from prostate cancer cells have potency to transform vascular endothelial cells into an angiogenic state

por Watanabe, Ryuta, Maekawa, Masashi, Kiyoi, Takeshi, Kurata, Mie, Miura, Noriyoshi, Kikugawa, Tadahiko, Higashiyama, Shigeki, Saika, Takashi
Publicado 2021