Broad-spectrum receptor tyrosine kinase inhibitors overcome de novo and acquired modes of resistance to EGFR-targeted therapies in colorectal cancer

por Graves-Deal, Ramona, Bogatcheva, Galina, Rehman, Saba, Lu, Yuanyuan, Higginbotham, James N., Singh, Bhuminder
Publicado 2019

Angiotensin-converting Enzyme 2–containing Small Extracellular Vesicles and Exomeres Bind the Severe Acute Respiratory Syndrome Coronavirus 2 Spike Protein

por Zhang, Qin, Jeppesen, Dennis K., Higginbotham, James N., Franklin, Jeffrey L., Crowe, James E., Coffey, Robert J.
Publicado 2021

The enterocyte microvillus is a vesicle-generating organelle

por McConnell, Russell E., Higginbotham, James N., Shifrin, David A., Tabb, David L., Coffey, Robert J., Tyska, Matthew J.
Publicado 2009

Identification and characterization of EGF receptor in individual exosomes by fluorescence-activated vesicle sorting

por Higginbotham, James N., Zhang, Qin, Jeppesen, Dennis K., Scott, Andrew M., Manning, H. Charles, Ochieng, Josiah, Franklin, Jeffrey L., Coffey, Robert J.
Publicado 2016

Circular RNAs are down-regulated in KRAS mutant colon cancer cells and can be transferred to exosomes

por Dou, Yongchao, Cha, Diana J., Franklin, Jeffrey L., Higginbotham, James N., Jeppesen, Dennis K., Weaver, Alissa M., Prasad, Nripesh, Levy, Shawn, Coffey, Robert J., Patton, James G., Zhang, Bing
Publicado 2016

Electrodeposited magnetic nanoporous membrane for high-yield and high-throughput immunocapture of extracellular vesicles and lipoproteins

por Zhang, Chenguang, Huo, Xiaoye, Zhu, Yini, Higginbotham, James N., Cao, Zheng, Lu, Xin, Franklin, Jeffrey L., Vickers, Kasey C., Coffey, Robert J., Senapati, Satyajyoti, Wang, Ceming, Chang, Hsueh-Chia
Publicado 2022

KRAS-dependent sorting of miRNA to exosomes

por Cha, Diana J, Franklin, Jeffrey L, Dou, Yongchao, Liu, Qi, Higginbotham, James N, Demory Beckler, Michelle, Weaver, Alissa M, Vickers, Kasey, Prasad, Nirpesh, Levy, Shawn, Zhang, Bing, Coffey, Robert J, Patton, James G
Publicado 2015

Transfer of Functional Cargo in Exomeres

por Zhang, Qin, Higginbotham, James N., Jeppesen, Dennis K., Yang, Yu-Ping, Li, Wei, McKinley, Eliot T., Graves-Deal, Ramona, Ping, Jie, Britain, Colleen M., Dorsett, Kaitlyn A., Hartman, Celine L., Ford, David A., Allen, Ryan M., Vickers, Kasey C., Liu, Qi, Franklin, Jeffrey L., Bellis, Susan L., Coffey, Robert J.
Publicado 2019

Mutant KRAS Exosomes Alter the Metabolic State of Recipient Colonic Epithelial Cells

por Zhang, Qin, Jeppesen, Dennis K., Higginbotham, James N., Demory Beckler, Michelle, Poulin, Emily J., Walsh, Alex J., Skala, Melissa C., McKinley, Eliot T., Manning, H. Charles, Hight, Matthew R., Schulte, Michael L., Watt, Kimberly R., Ayers, G. Daniel, Wolf, Melissa M., Andrejeva, Gabriela, Rathmell, Jeffrey C., Franklin, Jeffrey L., Coffey, Robert J.
Publicado 2018

Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets

por Zhang, Qin, Jeppesen, Dennis K., Higginbotham, James N., Graves-Deal, Ramona, Trinh, Vincent Q., Ramirez, Marisol A., Sohn, Yoojin, Neininger, Abigail C., Taneja, Nilay, McKinley, Eliot T., Niitsu, Hiroaki, Cao, Zheng, Evans, Rachel, Glass, Sarah E., Ray, Kevin C., Fissell, William H., Hill, Salisha, Rose, Kristie Lindsey, Huh, Won Jae, Washington, Mary Kay, Ayers, Gregory Daniel, Burnette, Dylan T., Sharma, Shivani, Rome, Leonard H., Franklin, Jeffrey L., Lee, Youngmin A., Liu, Qi, Coffey, Robert J.
Publicado 2021

Phase 2 of extracellular RNA communication consortium charts next-generation approaches for extracellular RNA research

por Mateescu, Bogdan, Jones, Jennifer C., Alexander, Roger P., Alsop, Eric, An, Ji Yeong, Asghari, Mohammad, Boomgarden, Alex, Bouchareychas, Laura, Cayota, Alfonso, Chang, Hsueh-Chia, Charest, Al, Chiu, Daniel T., Coffey, Robert J., Das, Saumya, De Hoff, Peter, deMello, Andrew, D’Souza-Schorey, Crislyn, Elashoff, David, Eliato, Kiarash R., Franklin, Jeffrey L., Galas, David J., Gerstein, Mark B., Ghiran, Ionita H., Go, David B., Gould, Stephen, Grogan, Tristan R., Higginbotham, James N., Hladik, Florian, Huang, Tony Jun, Huo, Xiaoye, Hutchins, Elizabeth, Jeppesen, Dennis K., Jovanovic-Talisman, Tijana, Kim, Betty Y.S., Kim, Sung, Kim, Kyoung-Mee, Kim, Yong, Kitchen, Robert R., Knouse, Vaughan, LaPlante, Emily L., Lebrilla, Carlito B., Lee, L. James, Lennon, Kathleen M., Li, Guoping, Li, Feng, Li, Tieyi, Liu, Tao, Liu, Zirui, Maddox, Adam L., McCarthy, Kyle, Meechoovet, Bessie, Maniya, Nalin, Meng, Yingchao, Milosavljevic, Aleksandar, Min, Byoung-Hoon, Morey, Amber, Ng, Martin, Nolan, John, De Oliveira Junior, Getulio P., Paulaitis, Michael E., Phu, Tuan Anh, Raffai, Robert L., Reátegui, Eduardo, Roth, Matthew E., Routenberg, David A., Rozowsky, Joel, Rufo, Joseph, Senapati, Satyajyoti, Shachar, Sigal, Sharma, Himani, Sood, Anil K., Stavrakis, Stavros, Stürchler, Alessandra, Tewari, Muneesh, Tosar, Juan P., Tucker-Schwartz, Alexander K., Turchinovich, Andrey, Valkov, Nedyalka, Van Keuren-Jensen, Kendall, Vickers, Kasey C., Vojtech, Lucia, Vreeland, Wyatt N., Wang, Ceming, Wang, Kai, Wang, ZeYu, Welsh, Joshua A., Witwer, Kenneth W., Wong, David T.W., Xia, Jianping, Xie, Ya-Hong, Yang, Kaichun, Zaborowski, Mikołaj P., Zhang, Chenguang, Zhang, Qin, Zivkovic, Angela M., Laurent, Louise C.
Publicado 2022