Pegylated arginine deiminase drives arginine turnover and systemic autophagy to dictate energy metabolism

por Zhang, Yiming, Higgins, Cassandra B., Van Tine, Brian A., Bomalaski, John S., DeBosch, Brian J.
Publicado 2022

SIRT1 selectively exerts the metabolic protective effects of hepatocyte nicotinamide phosphoribosyltransferase

por Higgins, Cassandra B., Mayer, Allyson L., Zhang, Yiming, Franczyk, Michael, Ballentine, Samuel, Yoshino, Jun, DeBosch, Brian J.
Publicado 2022

Hepatocyte ALOXE3 is induced during adaptive fasting and enhances insulin sensitivity by activating hepatic PPARγ

por Higgins, Cassandra B., Zhang, Yiming, Mayer, Allyson L., Fujiwara, Hideji, Stothard, Alicyn I., Graham, Mark J., Swarts, Benjamin M., DeBosch, Brian J.
Publicado 2018

Hepatic arginase 2 (Arg2) is sufficient to convey the therapeutic metabolic effects of fasting

por Zhang, Yiming, Higgins, Cassandra B., Fortune, Hannah M., Chen, Phillip, Stothard, Alicyn I., Mayer, Allyson L., Swarts, Benjamin M., DeBosch, Brian J.
Publicado 2019

SLC2A8 (GLUT8) is a mammalian trehalose transporter required for trehalose-induced autophagy

por Mayer, Allyson L., Higgins, Cassandra B., Heitmeier, Monique R., Kraft, Thomas E., Qian, Xia, Crowley, Jan R., Hyrc, Krzysztof L., Beatty, Wandy L., Yarasheski, Kevin E., Hruz, Paul W., DeBosch, Brian J.
Publicado 2016

The tetraspanin transmembrane protein CD53 mediates dyslipidemia and integrates inflammatory and metabolic signaling in hepatocytes

por Higgins, Cassandra B., Adams, Joshua A., Ward, Matthew H., Greenberg, Zev J., Milewska, Małgorzata, Sun, Jiameng, Zhang, Yiming, Chiquetto Paracatu, Luana, Dong, Qian, Ballentine, Samuel, Li, Weikai, Wandzik, Ilona, Schuettpelz, Laura G., DeBosch, Brian J.
Publicado 2022