PAI-1 Expression Is Required for HDACi-Induced Proliferative Arrest in ras-Transformed Renal Epithelial Cells

por Higgins, Stephen P., Higgins, Craig E., Higgins, Paul J.
Publicado 2011

TGF-β1-Induced Expression of the Poor Prognosis SERPINE1/PAI-1 Gene Requires EGFR Signaling: A New Target for Anti-EGFR Therapy

por Samarakoon, Rohan, Higgins, Craig E., Higgins, Stephen P., Higgins, Paul J.
Publicado 2009

The TGF-β1/p53/PAI-1 Signaling Axis in Vascular Senescence: Role of Caveolin-1

por Samarakoon, Rohan, Higgins, Stephen P., Higgins, Craig E., Higgins, Paul J.
Publicado 2019

Chemical Antagonists of Plasminogen Activator Inhibitor-1: Mechanisms of Action and Therapeutic Potential in Vascular Disease

por Simone, Tessa M, Higgins, Stephen P, Higgins, Craig E, Lennartz, Michelle R, Higgins, Paul J
Publicado 2014

Redox-Induced Src Kinase and Caveolin-1 Signaling in TGF-β1-Initiated SMAD2/3 Activation and PAI-1 Expression

por Samarakoon, Rohan, Chitnis, Subhanir S., Higgins, Stephen P., Higgins, Craig E., Krepinsky, Joan C., Higgins, Paul J.
Publicado 2011

Complex Regulation of the Pericellular Proteolytic Microenvironment during Tumor Progression and Wound Repair: Functional Interactions between the Serine Protease and Matrix Metall...

por Wilkins-Port, Cynthia E., Higgins, Stephen P., Higgins, Craig E., Kobori-Hotchkiss, Issey, Higgins, Paul J.
Publicado 2012

PAI-1 is a Critical Upstream Regulator of the TGF-β1/EGF-Induced Invasive Phenotype in Mutant p53 Human Cutaneous Squamous Cell Carcinoma

por Wilkins-Port, Cynthia E., Higgins, Craig E., Freytag, Jennifer, Higgins, Stephen P., Carlson, J. Andrew, Higgins, Paul J.
Publicado 2007

PAI-1 Regulates the Invasive Phenotype in Human Cutaneous Squamous Cell Carcinoma

por Freytag, Jennifer, Wilkins-Port, Cynthia E., Higgins, Craig E., Carlson, J. Andrew, Noel, Agnes, Foidart, Jean-Michel, Higgins, Stephen P., Samarakoon, Rohan, Higgins, Paul J.
Publicado 2009

PAI-1: An Integrator of Cell Signaling and Migration

por Czekay, Ralf-Peter, Wilkins-Port, Cynthia E., Higgins, Stephen P., Freytag, Jennifer, Overstreet, Jessica M., Klein, R. Matthew, Higgins, Craig E., Samarakoon, Rohan, Higgins, Paul J.
Publicado 2011

The Genomic Response to TGF-β1 Dictates Failed Repair and Progression of Fibrotic Disease in the Obstructed Kidney

por Higgins, Craig E., Tang, Jiaqi, Higgins, Stephen P., Gifford, Cody C., Mian, Badar M., Jones, David M., Zhang, Wenzheng, Costello, Angelica, Conti, David J., Samarakoon, Rohan, Higgins, Paul J.
Publicado 2021