BAG6 regulates the quality control of a polytopic ERAD substrate

por Payapilly, Aishwarya, High, Stephen
Publicado 2014

SGTA associates with nascent membrane protein precursors

por Leznicki, Pawel, High, Stephen
Publicado 2020

A biochemical analysis of the constraints of tail-anchored protein biogenesis

por Leznicki, Pawel, Warwicker, Jim, High, Stephen
Publicado 2011

Mitochondrial antiviral-signalling protein is a client of the BAG6 protein quality control complex

por Roboti, Peristera, Lawless, Craig, High, Stephen
Publicado 2022

OST4 is a subunit of the mammalian oligosaccharyltransferase required for efficient N-glycosylation

por Dumax-Vorzet, Audrey, Roboti, Peristera, High, Stephen
Publicado 2013

SGTA regulates the cytosolic quality control of hydrophobic substrates

por Wunderley, Lydia, Leznicki, Pawel, Payapilly, Aishwarya, High, Stephen
Publicado 2014

Mechanistic insights into the inhibition of Sec61-dependent co- and post-translational translocation by mycolactone

por McKenna, Michael, Simmonds, Rachel E., High, Stephen
Publicado 2016

Mycolactone reveals the substrate-driven complexity of Sec61-dependent transmembrane protein biogenesis

por McKenna, Michael, Simmonds, Rachel E., High, Stephen
Publicado 2017

Human autoantibodies against the 54 kDa protein of the signal recognition particle block function at multiple stages

por Römisch, Karin, Miller, Frederick W, Dobberstein, Bernhard, High, Stephen
Publicado 2006

Reorientation of the first signal-anchor sequence during potassium channel biogenesis at the Sec61 complex

por Watson, Helen R., Wunderley, Lydia, Andreou, Tereza, Warwicker, Jim, High, Stephen
Publicado 2013

SMIM1, carrier of the Vel blood group, is a tail-anchored transmembrane protein and readily forms homodimers in a cell-free system

por Nylander, Anja, Leznicki, Pawel, Vidovic, Karina, High, Stephen, Olsson, Martin L.
Publicado 2020

TRC40 can deliver short secretory proteins to the Sec61 translocon

por Johnson, Nicholas, Vilardi, Fabio, Lang, Sven, Leznicki, Pawel, Zimmermann, Richard, High, Stephen
Publicado 2012

The Charcot Marie Tooth disease protein LITAF is a zinc-binding monotopic membrane protein

por Qin, Wenxia, Wunderley, Lydia, Barrett, Anne L., High, Stephen, Woodman, Philip G.
Publicado 2016

Multiple pathways facilitate the biogenesis of mammalian tail-anchored proteins

por Casson, Joseph, McKenna, Michael, Haßdenteufel, Sarah, Aviram, Naama, Zimmerman, Richard, High, Stephen
Publicado 2017

The use of tail-anchored protein chimeras to enhance liposomal cargo delivery

por Abdelrehim, Abbi, Shaltiel, Lior, Zhang, Ling, Barenholz, Yechezkel, High, Stephen, Harris, Lynda K.
Publicado 2019

Ipomoeassin-F disrupts multiple aspects of secretory protein biogenesis

por Roboti, Peristera, O’Keefe, Sarah, Duah, Kwabena B., Shi, Wei Q., High, Stephen
Publicado 2021

Co-translational biogenesis of lipid droplet integral membrane proteins

por Leznicki, Pawel, Schneider, Hayden O., Harvey, Jada V., Shi, Wei Q., High, Stephen
Publicado 2021

Mammalian SRP receptor switches the Sec61 translocase from Sec62 to SRP-dependent translocation

por Jadhav, Bhalchandra, McKenna, Michael, Johnson, Nicholas, High, Stephen, Sinning, Irmgard, Pool, Martin R.
Publicado 2015

Chaperone-Mediated Sec61 Channel Gating during ER Import of Small Precursor Proteins Overcomes Sec61 Inhibitor-Reinforced Energy Barrier

por Haßdenteufel, Sarah, Johnson, Nicholas, Paton, Adrienne W., Paton, James C., High, Stephen, Zimmermann, Richard
Publicado 2018

Binding of SGTA to Rpn13 selectively modulates protein quality control

por Leznicki, Pawel, Korac-Prlic, Jelena, Kliza, Katarzyna, Husnjak, Koraljka, Nyathi, Yvonne, Dikic, Ivan, High, Stephen
Publicado 2015