A Phase 1, Randomized, Double-Blind, Placebo-Controlled, Crossover Study to Evaluate the Pharmacodynamic Effects of VX-150, a Highly Selective Na(V)1.8 Inhibitor, in Healthy Male A...

por Hijma, Hemme J, Siebenga, Pieter S, de Kam, Marieke L, Groeneveld, Geert Jan
Publicado 2021

A phase I, randomized, double‐blind, placebo‐controlled, single‐ and multiple dose escalation study evaluating the safety, pharmacokinetics and pharmacodynamics of VX‐128, a highly...

por Hijma, Hemme J., van Brummelen, Emilie M. J., Siebenga, Pieter S., Groeneveld, Geert Jan
Publicado 2021

A crossover study evaluating the sex‐dependent and sensitizing effects of sleep deprivation using a nociceptive test battery in healthy subjects

por Hijma, Hemme, Koopmans, Ingrid, Klaassen, Erica, Doll, Robert Jan, Zuiker, Rob, Groeneveld, Geert Jan
Publicado 2022

Simultaneous measurement of intra-epidermal electric detection thresholds and evoked potentials for observation of nociceptive processing following sleep deprivation

por van den Berg, Boudewijn, Hijma, Hemme J., Koopmans, Ingrid, Doll, Robert J., Zuiker, Rob G. J. A., Groeneveld, Geert Jan, Buitenweg, Jan R.
Publicado 2022

Good Clinical Trials by removing defensive interpretation of Good Clinical Practice guidelines

por den Heijer, Jonas M., Heuberger, Jules A. A. C., Hijma, Hemme, Kruithof, Annelieke C., van Smeden, Jeroen, Groeneveld, Geert Jan, Burggraaf, Jacobus, Cohen, Adam
Publicado 2021

Systematic analysis of chromatin interactions at disease associated loci links novel candidate genes to inflammatory bowel disease

por Meddens, Claartje A., Harakalova, Magdalena, van den Dungen, Noortje A. M., Foroughi Asl, Hassan, Hijma, Hemme J., Cuppen, Edwin P. J. G., Björkegren, Johan L. M., Asselbergs, Folkert W., Nieuwenhuis, Edward E. S., Mokry, Michal
Publicado 2016

Students’ guide to documentation in clinical trials

por Heck, Johannes, Rath, Ann-Kathrin, Wons, Katrin, Schumacher, Carsten, Kutschenko, Anna, Noltemeyer, Nina, Ulaganathan, Sarana, Voßiek, Luca J., Hijma, Hemme, van Smeden, Jeroen, Schröder, Christoph, Stichtenoth, Dirk O., Wedemeyer, Heiner, Schindler, Christoph, Bosch, Jacobus J.
Publicado 2022