Axotrophin/MARCH7 acts as an E3 ubiquitin ligase and ubiquitinates tau protein in vitro impairing microtubule binding

por Flach, Katharina, Ramminger, Ellen, Hilbrich, Isabel, Arsalan-Werner, Annika, Albrecht, Franziska, Herrmann, Lydia, Goedert, Michel, Arendt, Thomas, Holzer, Max
Publicado 2014

Hook Proteins: Association with Alzheimer Pathology and Regulatory Role of Hook3 in Amyloid Beta Generation

por Herrmann, Lydia, Wiegmann, Caspar, Arsalan-Werner, Annika, Hilbrich, Isabel, Jäger, Carsten, Flach, Katharina, Suttkus, Anne, Lachmann, Ingolf, Arendt, Thomas, Holzer, Max
Publicado 2015

Novel Protein Kinase Inhibitors Related to Tau Pathology Modulate Tau Protein-Self Interaction Using a Luciferase Complementation Assay

por Holzer, Max, Schade, Nico, Opitz, Ansgar, Hilbrich, Isabel, Stieler, Jens, Vogel, Tim, Neukel, Valentina, Oberstadt, Moritz, Totzke, Frank, Schächtele, Christoph, Sippl, Wolfgang, Hilgeroth, Andreas
Publicado 2018

A glutaminyl cyclase-catalyzed α-synuclein modification identified in human synucleinopathies

por Hartlage-Rübsamen, Maike, Bluhm, Alexandra, Moceri, Sandra, Machner, Lisa, Köppen, Janett, Schenk, Mathias, Hilbrich, Isabel, Holzer, Max, Weidenfeller, Martin, Richter, Franziska, Coras, Roland, Serrano, Geidy E., Beach, Thomas G., Schilling, Stephan, von Hörsten, Stephan, Xiang, Wei, Schulze, Anja, Roßner, Steffen
Publicado 2021