In Vivo Activity and Pharmacokinetics of Nemorosone on Pancreatic Cancer Xenografts

por Wolf, Robert J., Hilger, Ralf A., Hoheisel, Jörg D., Werner, Jens, Holtrup, Frank
Publicado 2013

Opioid receptor activation triggering downregulation of cAMP improves effectiveness of anti-cancer drugs in treatment of glioblastoma

por Friesen, Claudia, Hormann, Inis, Roscher, Mareike, Fichtner, Iduna, Alt, Andreas, Hilger, Ralf, Debatin, Klaus-Michael, Miltner, Erich
Publicado 2014

Cell death sensitization of leukemia cells by opioid receptor activation

por Friesen, Claudia, Roscher, Mareike, Hormann, Inis, Fichtner, Iduna, Alt, Andreas, Hilger, Ralf A., Debatin, Klaus-Michael, Miltner, Erich
Publicado 2013

Evaluation of the drug‐drug interaction potential of treosulfan using a physiologically‐based pharmacokinetic modelling approach

por Schaller, Stephan, Martins, Frederico S., Balazki, Pavel, Böhm, Sonja, Baumgart, Joachim, Hilger, Ralf A., Beelen, Dietrich W., Hemmelmann, Claudia, Ring, Arne
Publicado 2021

Generation and Characterisation of Cisplatin-Resistant Non-Small Cell Lung Cancer Cell Lines Displaying a Stem-Like Signature

por Barr, Martin P., Gray, Steven G., Hoffmann, Andreas C., Hilger, Ralf A., Thomale, Juergen, O’Flaherty, John D., Fennell, Dean A., Richard, Derek, O’Leary, John J., O’Byrne, Kenneth J.
Publicado 2013

Correction: Generation and Characterisation of Cisplatin-Resistant Non-Small Cell Lung Cancer Cell Lines Displaying a Stem-Like Signature

por Barr, Martin P., Gray, Steven G., Hoffmann, Andreas C., Hilger, Ralf A., Thomale, Juergen, O’Flaherty, John D., Fennell, Dean A., Richard, Derek, O’Leary, John J., O’Byrne, Kenneth J.
Publicado 2020

Diphenhydramine increases the therapeutic window for platinum drugs by simultaneously sensitizing tumor cells and protecting normal cells

por Melnikova, Margarita, Wauer, Ulrike Sophie, Mendus, Diana, Hilger, Ralf Axel, Oliver, Trudy G., Mercer, Kim, Gohlke, Björn Oliver, Erdmann, Kati, Niederacher, Dieter, Neubauer, Hans, Buderath, Paul, Wimberger, Pauline, Kuhlmann, Jan Dominik, Thomale, Jürgen
Publicado 2020

TFEB-mediated lysosomal biogenesis and lysosomal drug sequestration confer resistance to MEK inhibition in pancreatic cancer

por Zhao, Ben, Dierichs, Laura, Gu, Jiang-Ning, Trajkovic-Arsic, Marija, Axel Hilger, Ralf, Savvatakis, Konstantinos, Vega-Rubin-de-Celis, Silvia, Liffers, Sven-Thorsten, Peña-Llopis, Samuel, Behrens, Diana, Hahn, Stephan, Siveke, Jens T., Lueong, Smiths S.
Publicado 2020

SAM-Competitive EZH2-Inhibitors Induce Platinum Resistance by EZH2-Independent Induction of ABC-Transporters

por Groß, Elisabeth, Hilger, Ralf-Axel, Schümann, Franziska Lea, Bauer, Marcus, Bouska, Alyssa, Rohde, Christian, Willscher, Edith, Lützkendorf, Jana, Müller, Lutz Peter, Edemir, Bayram, Mueller, Thomas, Herling, Marco, Binder, Mascha, Wickenhauser, Claudia, Iqbal, Javeed, Posern, Guido, Weber, Thomas
Publicado 2023