“I Feel Happy Again”: Methylphenidate Supports Health-Related Quality of Life in Survivors of Pediatric Brain Tumor

por Verity, Sarah J., Bell, Lauren, Ryles, Jade, Hill, Rebecca M.
Publicado 2022

SWK-03. Neuroimaging in CNS tumours: To GA , or not to GA, that is the question.

por Ryles, Jade, Ternent, Lisa, Halliday, Gail, Hill, Rebecca M, Bailey, Simon
Publicado 2022

MEDB-43. Development of a bioinformatics pipeline for identification of differential DNA methylation events associated with medulloblastoma relapse

por Kui, Christopher, Richardson, Stacey, Schwalbe, Edward C, Thompson, Dean, Keeling, Claire, Strathdee, Gordon, Dufour, Christelle, Bailey, Simon, Ramaswamy, Vijay, Clifford, Steven C, Hill, Rebecca M
Publicado 2022

MEDB-79. MYC-driven upregulation of thede novo serine and glycine pathway is a novel therapeutic target for Group 3 MYC-amplified Medulloblastoma

por Adiamah, Magretta, Lindsey, Janet C, Burté, Florence, Kohe, Sarah, Morcavallo, Alaide, Blair, Helen, Hill, Rebecca M, Singh, Mankaran, Crosier, Stephen, Zhang, Tong, Maddocks, Oliver, Peet, Andrew, Chesler, Louis, Hickson, Ian, Maxwell, Ross, Clifford, Steven C
Publicado 2022

Time, pattern, and outcome of medulloblastoma relapse and their association with tumour biology at diagnosis and therapy: a multicentre cohort study

por Hill, Rebecca M, Richardson, Stacey, Schwalbe, Edward C, Hicks, Debbie, Lindsey, Janet C, Crosier, Stephen, Rafiee, Gholamreza, Grabovska, Yura, Wharton, Stephen B, Jacques, Thomas S, Michalski, Antony, Joshi, Abhijit, Pizer, Barry, Williamson, Daniel, Bailey, Simon, Clifford, Steven C
Publicado 2020

Single-cell DNA sequencing identifies risk-associated clonal complexity and evolutionary trajectories in childhood medulloblastoma development

por Danilenko, Marina, Zaka, Masood, Keeling, Claire, Crosier, Stephen, Lyman, Stephanie, Finetti, Martina, Williamson, Daniel, Hussain, Rafiqul, Coxhead, Jonathan, Zhou, Peixun, Hill, Rebecca M., Hicks, Debbie, Rand, Vikki, Joshi, Abhijit, Schwalbe, Edward C., Bailey, Simon, Clifford, Steven C.
Publicado 2022

Relapsed Medulloblastoma in Pre-Irradiated Patients: Current Practice for Diagnostics and Treatment

por Hill, Rebecca M., Plasschaert, Sabine L. A., Timmermann, Beate, Dufour, Christelle, Aquilina, Kristian, Avula, Shivaram, Donovan, Laura, Lequin, Maarten, Pietsch, Torsten, Thomale, Ulrich, Tippelt, Stephan, Wesseling, Pieter, Rutkowski, Stefan, Clifford, Steven C., Pfister, Stefan M., Bailey, Simon, Fleischhack, Gudrun
Publicado 2021

ARF suppression by MYC but not MYCN confers increased malignancy of aggressive pediatric brain tumors

por Mainwaring, Oliver J., Weishaupt, Holger, Zhao, Miao, Rosén, Gabriela, Borgenvik, Anna, Breinschmid, Laura, Verbaan, Annemieke D., Richardson, Stacey, Thompson, Dean, Clifford, Steven C., Hill, Rebecca M., Annusver, Karl, Sundström, Anders, Holmberg, Karl O., Kasper, Maria, Hutter, Sonja, Swartling, Fredrik J.
Publicado 2023

Novel molecular subgroups for clinical classification and outcome prediction in childhood medulloblastoma: a cohort study

por Schwalbe, Edward C, Lindsey, Janet C, Nakjang, Sirintra, Crosier, Stephen, Smith, Amanda J, Hicks, Debbie, Rafiee, Gholamreza, Hill, Rebecca M, Iliasova, Alice, Stone, Thomas, Pizer, Barry, Michalski, Antony, Joshi, Abhijit, Wharton, Stephen B, Jacques, Thomas S, Bailey, Simon, Williamson, Daniel, Clifford, Steven C
Publicado 2017

Medulloblastoma group 3 and 4 tumors comprise a clinically and biologically significant expression continuum reflecting human cerebellar development

por Williamson, Daniel, Schwalbe, Edward C., Hicks, Debbie, Aldinger, Kimberly A., Lindsey, Janet C., Crosier, Stephen, Richardson, Stacey, Goddard, Jack, Hill, Rebecca M., Castle, Jemma, Grabovska, Yura, Hacking, James, Pizer, Barry, Wharton, Stephen B., Jacques, Thomas S., Joshi, Abhijit, Bailey, Simon, Clifford, Steven C.
Publicado 2022

MBRS-60. THE ACTIONABLE GENOMIC LANDSCAPE OF RELAPSED MEDULLOBLASTOMA IS DEFINED BY MAINTENANCE AND ACQUISITION OF DRIVER EVENTS

por Richardson, Stacey, Hill, Rebecca M, Kui, Christopher, Lindsey, Janet C, Grabovska, Yura, Schwalbe, Edward C, Hicks, Debbie, Williamson, Daniel, Crosier, Stephen, Joshi, Abjhit, Wharton, Stephen B, Hansford, Jordan, Pizer, Barry, Vinci, Maria, Mastronuzzi, Angela, Carai, Andrea, Michalski, Anthony, Jacques, Thomas S, Bailey, Simon, Clifford, Steven C
Publicado 2020

MEDB-71. Molecular characterisation of group 4 medulloblastoma improves risk-stratification and its biological understanding

por Goddard, Jack, Castle, Jemma, Southworth, Emily, Fletcher, Anya, Crosier, Stephen, Martin-Guerrero, Idoia, Garcia-Ariza, Miguel, Navajas, Aurora, Masliah-Planchon, Julien, Bourdeaut, Franck, Dufour, Christelle, Goschizk, Tobias, Pietsch, Torsten, Richardson, Stacey, Hill, Rebecca M, Williamson, Daniel, Bailey, Simon, Schwalbe, Edward C, Clifford, Steven C, Hicks, Debbie
Publicado 2022

Molecular characterisation defines clinically-actionable heterogeneity within Group 4 medulloblastoma and improves disease risk-stratification

por Goddard, Jack, Castle, Jemma, Southworth, Emily, Fletcher, Anya, Crosier, Stephen, Martin-Guerrero, Idoia, García-Ariza, Miguel, Navajas, Aurora, Masliah-Planchon, Julien, Bourdeaut, Franck, Dufour, Christelle, Ayrault, Olivier, Goschzik, Tobias, Pietsch, Torsten, Sill, Martin, Pfister, Stefan M., Rutkowski, Stefan, Richardson, Stacey, Hill, Rebecca M., Williamson, Daniel, Bailey, Simon, Schwalbe, Edward C., Clifford, Steven C., Hicks, Debbie
Publicado 2023

Second-generation molecular subgrouping of medulloblastoma: an international meta-analysis of Group 3 and Group 4 subtypes

por Sharma, Tanvi, Schwalbe, Edward C., Williamson, Daniel, Sill, Martin, Hovestadt, Volker, Mynarek, Martin, Rutkowski, Stefan, Robinson, Giles W., Gajjar, Amar, Cavalli, Florence, Ramaswamy, Vijay, Taylor, Michael D., Lindsey, Janet C., Hill, Rebecca M., Jäger, Natalie, Korshunov, Andrey, Hicks, Debbie, Bailey, Simon, Kool, Marcel, Chavez, Lukas, Northcott, Paul A., Pfister, Stefan M., Clifford, Steven C.
Publicado 2019

Development of a targeted sequencing approach to identify prognostic, predictive and diagnostic markers in paediatric solid tumours

por Izquierdo, Elisa, Yuan, Lina, George, Sally, Hubank, Michael, Jones, Chris, Proszek, Paula, Shipley, Janet, Gatz, Susanne A., Stinson, Caedyn, Moore, Andrew S., Clifford, Steven C., Hicks, Debbie, Lindsey, Janet C., Hill, Rebecca M., Jacques, Thomas S., Chalker, Jane, Thway, Khin, O’Connor, Simon, Marshall, Lynley, Moreno, Lucas, Pearson, Andrew, Chesler, Louis, Walker, Brian A., De Castro, David Gonzalez
Publicado 2017

MBRS-10. QUIESCENT SOX9-POSITIVE CELLS BEHIND MYC DRIVEN MEDULLOBLASTOMA RECURRENCE

por Bolin, Sara, Savov, Vasil, Borgenvik, Anna, Rosén, Gabriela, Olausson, Karl Holmberg, Zhao, Miao, Garancher, Alexandra, Rahmanto, Aldwin Suryo, Hutter, Sonja, Mainwaring, Oliver, Rusert, Jessica, Sundstrom, Anders, Richardson, Stacey, Fotaki, Grammatiki, Hill, Rebecca M, Dubuc, Adrian M, Kalushkova, Antonia, Remke, Marc, Čančer, Matko, Jernberg-Wiklund, Helena, Ramaswamy, Vijay, Chen, Xingqi, Taylor, Michael D, Sangfelt, Olle, Schüller, Ulrich, Clifford, Steve C, Wechsler-Reya, Robert J, Weishaupt, Holger, Swartling, Fredrik J
Publicado 2020

Emergence and maintenance of actionable genetic drivers at medulloblastoma relapse

por Richardson, Stacey, Hill, Rebecca M, Kui, Christopher, Lindsey, Janet C, Grabovksa, Yura, Keeling, Claire, Pease, Louise, Bashton, Matthew, Crosier, Stephen, Vinci, Maria, André, Nicolas, Figarella-Branger, Dominique, Hansford, Jordan R, Lastowska, Maria, Zakrzewski, Krzysztof, Jorgensen, Mette, Pickles, Jessica C, Taylor, Michael D, Pfister, Stefan M, Wharton, Stephen B, Pizer, Barry, Michalski, Antony, Joshi, Abhijit, Jacques, Thomas S, Hicks, Debbie, Schwalbe, Edward C, Williamson, Daniel, Ramaswamy, Vijay, Bailey, Simon, Clifford, Steven C
Publicado 2021

Combined MYC and P53 Defects Emerge at Medulloblastoma Relapse and Define Rapidly Progressive, Therapeutically Targetable Disease

por Hill, Rebecca M., Kuijper, Sanne, Lindsey, Janet C., Petrie, Kevin, Schwalbe, Ed C., Barker, Karen, Boult, Jessica K.R., Williamson, Daniel, Ahmad, Zai, Hallsworth, Albert, Ryan, Sarra L., Poon, Evon, Robinson, Simon P., Ruddle, Ruth, Raynaud, Florence I., Howell, Louise, Kwok, Colin, Joshi, Abhijit, Nicholson, Sarah Leigh, Crosier, Stephen, Ellison, David W., Wharton, Stephen B., Robson, Keith, Michalski, Antony, Hargrave, Darren, Jacques, Thomas S., Pizer, Barry, Bailey, Simon, Swartling, Fredrik J., Weiss, William A., Chesler, Louis, Clifford, Steven C.
Publicado 2015

Dormant SOX9-Positive Cells Facilitate MYC-Driven Recurrence of Medulloblastoma

por Borgenvik, Anna, Holmberg, Karl O., Bolin, Sara, Zhao, Miao, Savov, Vasil, Rosén, Gabriela, Hutter, Sonja, Garancher, Alexandra, Rahmanto, Aldwin Suryo, Bergström, Tobias, Olsen, Thale Kristin, Mainwaring, Oliver J., Sattanino, Damiana, Verbaan, Annemieke D., Rusert, Jessica M., Sundström, Anders, Bravo, Mar Ballester, Dang, Yonglong, Wenz, Amelie S., Richardson, Stacey, Fotaki, Grammatiki, Hill, Rebecca M., Dubuc, Adrian M., Kalushkova, Antonia, Remke, Marc, Čančer, Matko, Jernberg-Wiklund, Helena, Giraud, Géraldine, Chen, Xingqi, Taylor, Michael D., Sangfelt, Olle, Clifford, Steven C., Schüller, Ulrich, Wechsler-Reya, Robert J., Weishaupt, Holger, Swartling, Fredrik J.
Publicado 2022