Effects of four different antihypertensive drugs on plasma metabolomic profiles in patients with essential hypertension

por Hiltunen, Timo P., Rimpelä, Jenni M., Mohney, Robert P., Stirdivant, Steven M., Kontula, Kimmo K.
Publicado 2017

Effect of four classes of antihypertensive drugs on cardiac repolarization heterogeneity: A double-blind rotational study

por Sánez Tähtisalo, Heini, Hiltunen, Timo P., Kenttä, Tuomas, Junttila, Juhani, Oikarinen, Lasse, Virolainen, Juha, Kontula, Kimmo K., Porthan, Kimmo
Publicado 2020

Pharmacoepigenetics of hypertension: genome-wide methylation analysis of responsiveness to four classes of antihypertensive drugs using a double-blind crossover study design

por Nuotio, Marja-Liisa, Sánez Tähtisalo, Heini, Lahtinen, Alexandra, Donner, Kati, Fyhrquist, Frej, Perola, Markus, Kontula, Kimmo K, Hiltunen, Timo P
Publicado 2022

Human essential hypertension: no significant association of polygenic risk scores with antihypertensive drug responses

por Sánez Tähtisalo, Heini, Ruotsalainen, Sanni, Mars, Nina, Porthan, Kimmo, Oikarinen, Lasse, Virolainen, Juha, Fyhrquist, Frej, Ripatti, Samuli, Kontula, Kimmo K., Hiltunen, Timo P.
Publicado 2020

L-type calcium channel blocker increases VEGF concentrations in retinal cells and human serum

por Kumar, Anmol, Mutter, Stefan, Parente, Erika B., Harjutsalo, Valma, Lithovius, Raija, Mathavan, Sinnakaruppan, Lehto, Markku, Hiltunen, Timo P., Kontula, Kimmo K., Groop, Per-Henrik
Publicado 2023

Chromosomal Region 11p14.1 is Associated with Pharmacokinetics and Pharmacodynamics of Bisoprolol

por Fontana, Vanessa, Turner, Richard Myles, Francis, Ben, Yin, Peng, Pütz, Benno, Hiltunen, Timo P, Ruotsalainen, Sanni, Kontula, Kimmo K, Müller-Myhsok, Bertam, Pirmohamed, Munir
Publicado 2022

Genome-wide association study of nocturnal blood pressure dipping in hypertensive patients

por Rimpelä, Jenni M., Pörsti, Ilkka H., Jula, Antti, Lehtimäki, Terho, Niiranen, Teemu J., Oikarinen, Lasse, Porthan, Kimmo, Tikkakoski, Antti, Virolainen, Juha, Kontula, Kimmo K., Hiltunen, Timo P.
Publicado 2018

Common variants of the beta and gamma subunits of the epithelial sodium channel and their relation to plasma renin and aldosterone levels in essential hypertension

por Hannila-Handelberg, Tuula, Kontula, Kimmo, Tikkanen, Ilkka, Tikkanen, Tuula, Fyhrquist, Frej, Helin, Karri, Fodstad, Heidi, Piippo, Kirsi, Miettinen, Helena E, Virtamo, Jarmo, Krusius, Tom, Sarna, Seppo, Gautschi, Ivan, Schild, Laurent, Hiltunen, Timo P
Publicado 2005

Pharmacogenomics of Hypertension: A Genome‐Wide, Placebo‐Controlled Cross‐Over Study, Using Four Classes of Antihypertensive Drugs

por Hiltunen, Timo P., Donner, Kati M., Sarin, Antti‐Pekka, Saarela, Janna, Ripatti, Samuli, Chapman, Arlene B., Gums, John G., Gong, Yan, Cooper‐DeHoff, Rhonda M., Frau, Francesca, Glorioso, Valeria, Zaninello, Roberta, Salvi, Erika, Glorioso, Nicola, Boerwinkle, Eric, Turner, Stephen T., Johnson, Julie A., Kontula, Kimmo K.
Publicado 2015

Genome‐Wide Meta‐Analysis of Blood Pressure Response to β(1)‐Blockers: Results From ICAPS (International Consortium of Antihypertensive Pharmacogenomics Studies)

por Singh, Sonal, Warren, Helen R., Hiltunen, Timo P., McDonough, Caitrin W., El Rouby, Nihal, Salvi, Erika, Wang, Zhiying, Garofalidou, Tatiana, Fyhrquist, Frej, Kontula, Kimmo K., Glorioso, Valeria, Zaninello, Roberta, Glorioso, Nicola, Pepine, Carl J., Munroe, Patricia B., Turner, Stephan T., Chapman, Arlene B., Boerwinkle, Eric, Johnson, Julie A., Gong, Yan, Cooper‐DeHoff, Rhonda M.
Publicado 2019