Covalent DNA Binding Is Essential for Gram-Negative Antibacterial Activity of Broad Spectrum Pyrrolobenzodiazepines

por Picconi, Pietro, Hind, Charlotte K., Sutton, J. Mark, Rahman, Khondaker Miraz
Publicado 2022

Evaluation of a Library of FDA-Approved Drugs for Their Ability To Potentiate Antibiotics against Multidrug-Resistant Gram-Negative Pathogens

por Hind, Charlotte K., Dowson, Christopher G., Sutton, J. Mark, Jackson, Thomas, Clifford, Melanie, Garner, R. Colin, Czaplewski, Lloyd
Publicado 2019

N1-Benzofused Modification of Fluoroquinolones Reduces Activity Against Gram-Negative Bacteria

por Laws, Mark, Hind, Charlotte, Favaron, Andrea, Jamshidi, Shirin, Evans, Bonnie, Clifford, Melanie, Sutton, J. Mark, Rahman, Khondaker Miraz
Publicado 2020

Schiff bases of sulphonamides as a new class of antifungal agent against multidrug‐resistant Candida auris

por Hamad, Asad, Chen, Yiyuan, Khan, Mohsin A., Jamshidi, Shirin, Saeed, Naima, Clifford, Melanie, Hind, Charlotte, Sutton, J. Mark, Rahman, Khondaker Miraz
Publicado 2021

Temporin B Forms Hetero-Oligomers with Temporin L, Modifies Its Membrane Activity, and Increases the Cooperativity of Its Antibacterial Pharmacodynamic Profile

por Ferguson, Philip M., Clarke, Maria, Manzo, Giorgia, Hind, Charlotte K., Clifford, Melanie, Sutton, J. Mark, Lorenz, Christian D., Phoenix, David A., Mason, A. James
Publicado 2022

Revisiting unexploited antibiotics in search of new antibacterial drug candidates: the case of γ-actinorhodin

por Nass, Nada M., Farooque, Sannia, Hind, Charlotte, Wand, Matthew E., Randall, Christopher P., Sutton, J. Mark, Seipke, Ryan F., Rayner, Christopher M., O’Neill, Alex J.
Publicado 2017

Nuclear Magnetic Resonance Metabolomics of Symbioses between Bacterial Vaginosis-Associated Bacteria

por Horrocks, Victoria, Hind, Charlotte K., Wand, Matthew E., Fady, Paul-Enguerrand, Chan, Joel, Hopkins, Jade C., Houston, Georgina L., Tribe, Rachel M., Sutton, J. Mark, Mason, A. James
Publicado 2022

Antimicrobial Constituents from Machaerium Pers.: Inhibitory Activities and Synergism of Machaeriols and Machaeridiols against Methicillin-Resistant Staphylococcus aureus, Vancomyc...

por Muhammad, Ilias, Jacob, Melissa R., Ibrahim, Mohamed A., Raman, Vijayasankar, Kumarihamy, Mallika, Wang, Mei, Al-Adhami, Taha, Hind, Charlotte, Clifford, Melanie, Martin, Bethany, Zhao, Jianping, Sutton, J. Mark, Rahman, Khondaker Miraz
Publicado 2020

Bactericidal and anti-biofilm effects of uncharged and cationic ultrasound-responsive nitric oxide microbubbles on Pseudomonas aeruginosa biofilms

por LuTheryn, Gareth, Hind, Charlotte, Campbell, Christopher, Crowther, Aaron, Wu, Qiang, Keller, Sara B., Glynne-Jones, Peter, Sutton, J. Mark, Webb, Jeremy S., Gray, Michael, Wilks, Sandra A., Stride, Eleanor, Carugo, Dario
Publicado 2022

Minor sequence modifications in temporin B cause drastic changes in antibacterial potency and selectivity by fundamentally altering membrane activity

por Manzo, Giorgia, Ferguson, Philip M., Gustilo, V. Benjamin, Hind, Charlotte K., Clifford, Melanie, Bui, Tam T., Drake, Alex F., Atkinson, R. Andrew, Sutton, J. Mark, Batoni, Giovanna, Lorenz, Christian D., Phoenix, David A., Mason, A. James
Publicado 2019

Fluoxetine and thioridazine inhibit efflux and attenuate crystalline biofilm formation by Proteus mirabilis

por Nzakizwanayo, Jonathan, Scavone, Paola, Jamshidi, Shirin, Hawthorne, Joseph A., Pelling, Harriet, Dedi, Cinzia, Salvage, Jonathan P., Hind, Charlotte K., Guppy, Fergus M., Barnes, Lara M., Patel, Bhavik A., Rahman, Khondaker M., Sutton, Mark J., Jones, Brian V.
Publicado 2017

Temporin L and aurein 2.5 have identical conformations but subtly distinct membrane and antibacterial activities

por Manzo, Giorgia, Ferguson, Philip M., Hind, Charlotte K., Clifford, Melanie, Gustilo, V. Benjamin, Ali, Hind, Bansal, Sukhvinder S., Bui, Tam T., Drake, Alex F., Atkinson, R. Andrew, Sutton, J. Mark, Lorenz, Christian D., Phoenix, David A., Mason, A. James
Publicado 2019

Insights into the Spectrum of Activity and Mechanism of Action of MGB-BP-3

por Hind, Charlotte, Clifford, Melanie, Woolley, Charlotte, Harmer, Jane, McGee, Leah M. C., Tyson-Hirst, Izaak, Tait, Henry J., Brooke, Daniel P., Dancer, Stephanie J., Hunter, Iain S., Suckling, Colin J., Beveridge, Rebecca, Parkinson, John A., Sutton, J. Mark, Scott, Fraser J.
Publicado 2022

Establishing the selective phospholipid membrane coordination, permeation and lysis properties for a series of ‘druggable’ supramolecular self-associating antimicrobial amphiphiles...

por Boles, Jessica E., Bennett, Charlotte, Baker, Jennifer, Hilton, Kira L. F., Kotak, Hiral A., Clark, Ewan R., Long, Yifan, White, Lisa J., Lai, Hin Yuk, Hind, Charlotte K., Sutton, J. Mark, Garrett, Michelle D., Cheasty, Anne, Ortega-Roldan, Jose L., Charles, Mark, Haynes, Cally J. E., Hiscock, Jennifer R.
Publicado 2022

Bolaamphiphile Analogues of 12-bis-THA Cl(2) Are Potent Antimicrobial Therapeutics with Distinct Mechanisms of Action against Bacterial, Mycobacterial, and Fungal Pathogens

por Di Blasio, Simona, Clarke, Maria, Hind, Charlotte K., Asai, Masanori, Laurence, Louis, Benvenuti, Angelica, Hassan, Mahnoor, Semenya, Dorothy, Man, DeDe Kwun-Wai, Horrocks, Victoria, Manzo, Giorgia, Van Der Lith, Sarah, Lam, Carolyn, Gentile, Eugenio, Annette, Callum, Bosse, Janine, Li, Yanwen, Panaretou, Barry, Langford, Paul R., Robertson, Brian D., Lam, Jenny K. W., Sutton, J. Mark, McArthur, Michael, Mason, A. James
Publicado 2022

A pleurocidin analogue with greater conformational flexibility, enhanced antimicrobial potency and in vivo therapeutic efficacy

por Manzo, Giorgia, Hind, Charlotte K., Ferguson, Philip M., Amison, Richard T., Hodgson-Casson, Alice C., Ciazynska, Katarzyna A., Weller, Bethany J., Clarke, Maria, Lam, Carolyn, Man, Rico C. H., Shaughnessy, Blaze G. O’, Clifford, Melanie, Bui, Tam T., Drake, Alex F., Atkinson, R. Andrew, Lam, Jenny K. W., Pitchford, Simon C., Page, Clive P., Phoenix, David A., Lorenz, Christian D., Sutton, J. Mark, Mason, A. James
Publicado 2020